Until now, patient-specific regulatory networks have mostly been studied in individual cancer types. In our latest BioRxiv pre-print, we took this to the next level, performing a large-scale, pan-cancer network analysis of patient-specific regulatory landscapes: www.biorxiv.org/content/10.1...

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...

Very excited to announce that the single cell/nuc. RNA/ATAC/multi-ome resource from ENCODE4 is now officially public. This includes raw data, processed data, annotations and pseudobulk products. Covers many human & mouse tissues. 1/

www.encodeproject.org/single-cell/...

On metrics for subpopulation detection in single-cell and spatial omics data Benchmarks are crucial to understanding the strengths and weaknesses of the growing number of tools for single-cell and spatial omics analysis. A key task is to distinguish subpopulations within compl...

www.biorxiv.org/content/10.1...

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Impacts of Cell Ranger versions on Chromium gene expression data In droplet-based Chromium single cell gene expression data by the 10x Genomics platform, cell barcode calling by Cell Ranger (CR) is a standard pipeline. However, no systematic evaluation of the impac...

15 versions of 10x Genomics Cell Ranger, 15 different results—Consistency in single-cell analysis is still a work in progress biorxiv.org/cgi/content/...