Are polygenic scores for psychiatric and substance use... : Psychiatric Genetics of medicine where polygenic scores (PGS) are already being incorporated. We evaluate current PGS across three areas of psychiatry (depression, substance use disorders, and schizophrenia) against the criteria used by the National Electronic Medical Records and Genomics consortium to select PGS to study in a clinical context, finding that the PGS for psychiatric conditions are comparable to the PGS being implemented in clinical practice for other medical conditions. We conclude by discussing ne...

PGS for psychiatric outcomes are often labeled “not ready.” But many tools already used in medicine aren’t perfect—they’re useful.

In my new paper: Let’s move beyond readiness → and start asking how these tools can be used to improve prevention and care. ➡️ https://loom.ly/LKEC-ZI

Latest Claude Cowork love - three of my recent papers and full conference program uploaded and voila! Personalized conference schedule in seconds.

Secondarily, when did conference programs get so long and overcomplicated and why do these apps just make them worse?

Here's another feeding trial of ultra-processed foods vs. minimally processed.

Which group consumed more calories? NEITHER.

Why? Because the study controlled for calorie-density, which is probably the main driver of the overconsumption of UPFs.

onlinelibrary.wiley.com/doi/pdf/10.1...

After 150 years of boring wooden Galton boards, I finally fixed it!

Now with lasers, bazookas, bombs, pinball bumpers, and extremely serious sci-fi hamsters.

🎯 EXTREME GALTON 👇

sachaepskamp.com/extreme_galton

oh cool! What's that golden cylinder next to the player?

The trials that quietly changed our lives Testing claims matters more than ever in an age of misinformation, overconfident assertions and unsubstantiated opinions

My article in the Financial Times about my book. It includes a wonderful randomised trial of beer glasses (which you might unknowingly have been part of if you bought a pint in some British pubs c.1998)

“Testing claims matters more than ever in an age of misinformation”
as.ft.com/r/f5a2f313-a...

Exam prep for a research and statistics exam in 2026!

sachaepskamp.com/PL2132_games...

oh, there's a record player in the office?

What did you get? 💿

It's an invitation only review journal, they tend to be highly cited. Like Annual Reviews

The Biggest Threat to Online Data Collection Is Humans, Not Bots Concerns about bots answering online surveys are exaggerated, but a new threat is emerging in artificial intelligence agents.

Psychological scientists are determined to figure out the best practices for online surveys, who—or what—is behind bad data, and how to best protect surveys from the new and emerging threat of #AI. @justinsulik.bsky.social

Research poster by Zhao, Fisher, Parry, and Huskey presenting a large-scale, multi-site, pre-registered study on TikTok use and attention. Key finding: near-null effects on executive control and orienting; TikTok users show higher alerting efficiency than non-users, suggesting a stimulus-reactive attentional profile rather than impairment.

Also today at #SANS2026, Ziyu Zhao investigates the “brain rot” hypothesis. When studied rigorously, in large multi-national samples, we find a whole lot of nothing. Conclusion: previously observed alarming results might be driven by sampling bias and/or measurement error (P1-C-20)

Here’s the actual truth about the “Narva People’s Republic” (NPR) that made the rounds on social media recently. @martinlaineolen.bsky.social dug deep and discovered who is most likely behind that campaign. HINT: It’s not the GRU or the FSB 🧵 1/

balticflank.substack.com/p/unmasking-...

Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting Nature Genetics - Multi-ancestry GWAS meta-analysis identifies risk loci for severe nausea and vomiting of pregnancy. Downstream analyses explore maternal and fetal contributions of these loci and...

Thrilled to see this out. What started out as a chat several years back with @drfejzo.bsky.social about leveraging publicly available data on hyperemesis gravidarum GWAS turned into a wonderful collaboration with April Shu, @mvaudel.bsky.social, @xwww.bsky.social and many others!

rdcu.be/fdl9k

Excellent thread by @bogatatimar.bsky.social about how Hungarians feel about the elections and Magyar, warts and all. Highly recommend read

"It seem that you guys seem to have zero clue what happened in #Hungary in the last two years, you completely miss the point!" 🧵 1/

Grok summary is spot on 😆

Congrats to Hungary!

Are different desires (e.g., food, sleep, alcohol, cannabis) experienced and regulated the same way? We tested this question in a new preprint with Yang Liu, @minzlicht.bsky.social, @wilhelmhofmann.bsky.social, and @kevinmking.bsky.social: osf.io/preprints/ps...

Can we estimate assortative mating for outcomes shared by partners? Yes we can! In a new paper together with @philippdierker.bsky.social, I find that individuals with similar liabilities to divorce are more likely to get married in the first place!

Ordi – Vikipeedia Ordi asutati Tartus 1992. aasta kevadel ja ettevõte müüs toona arvuteid ja arvutikaupu.[6] 1994. aastal laiendas Ordi tegevust ja valmis esimene selle logo kandev arvuti[6]. Firma pakkus ka arvutite hoolduse teenust.

One of our main tech shops used to be called Ordi

et.wikipedia.org/wiki/Ordi

Personality does not work so well for typologies. More like a continuous probability.

That being said, we do have a scientific engine for suggesting suitable jobs

whichjob.me

Genetic predictors of GLP1 receptor agonist weight loss and side effects - Nature Identification of genetic variants associated with the efficacy and side effects of GLP1 medications could underpin development of precision medicine approaches in the treatment of obesity.

Were you inspired by our paper on the genetics of GLP-1 drug response? www.nature.com/articles/s41...

Want to make impactful discoveries with the world's best genetic dataset? We're hiring!

StatGen: tinyurl.com/ys4mvhej
Risk Prediction: tinyurl.com/psamt294
Data Products: tinyurl.com/2ff7eavb

Congrats! Very cool that you also replicated in Electronic Health Records! What was the average follow-up period length in the EHR?

Separated Bike Lanes Means Safer Streets, Study Says — Streetsblog USA Cities that build protected lanes for cyclists end up with safer roads for people on bikes and people in cars and on foot, a new study of 12 large metropolises revealed Wednesday.

Never forget, a 13-year study found that protected bike-lanes led to a drastic decline in fatalities for all road users.

ALL ROAD USERS.

What about painted bike-lanes? No safety improvement at all.

For sharrows, it’s actually safer to NOT have them.

Via @usa.streetsblog.org @nyc.streetsblog.org

1/ Goldman Sachs analysts report that the biggest oil crisis in history is about to hit globally, with profound and highly destructive consequences. A new report asks ""Are We Running Out of Oil?", and concludes that the answer is yes. ⬇️

Incredible footage from a United Airlines flight of the Artemis II launch.

Two common misconceptions when repurposing data for #causalinference:
1) the target trial is an ideal trial
2) the target trial protocol can be prespecified

Our new paper examines how the target trial protocol depends on the causal question AND the available data.

journals.lww.com/epidem/abstr...

Reliable research in the social and behavioural and sciences Sweeping new investigations probe the replication, robustness and reproducibility of results across the behavioural and social sciences.

Today, the SCORE program releases its primary results! 865 researchers examined research credibility across the social and behavioral sciences, publishing three papers in Nature + five preprints.

📑 Explore the papers: www.nature.com/colle...
ℹ️ Read more about SCORE: www.cos.io/score

#Trump starts a war in the Gulf - sending oil prices into the stratosphere.
#Trump drops sanctions on Iranian oil - doubling their foreign revenue income.
#Trump leaves Iran in control of the Strait of Hormuz.

Are we 𝘴𝘶𝘳𝘦 #Trump isn't working for the Iranians?
🤔

Postdoc in Epidemiology - Vacancy at Aarhus University Vacancy at Department of Public Health - Department of Epidemiology, Aarhus University

🤓There's an open 2 yr postdoc position in my group
🏘️ On interactions between area-level socioeconomic position and environmental factors in weight trajectories in children
📈 Using multilevel models; applying the target trial framework
📆 Apply before April 7th!
international.au.dk/about/profil...

💼 Three postdoc positions: Genomics and life paths (Uppsala, Amsterdam and Oslo)

bga.org/content.aspx...