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Confocal cross section of a regenerating tadpole limb. Focus on regenerative skin cell formation.

Confocal cross section of a regenerating tadpole limb. Focus on regenerative skin cell formation.

Two new Science studies in mice explore the roots of vertebrate limb regeneration and show that manipulating tissue mechanics, oxygen levels, and epigenetic signals can unlock regenerative potential.

📄: https://scim.ag/4sBQ93R
📄: https://scim.ag/4dL0MxA

2 days ago 53 6 0 0

Thank you so much Filipa!

4 days ago 1 0 0 0

Thank you, Wayo! :)

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Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...

🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders?
In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸
🔗 www.science.org/doi/10.1126/... #EvoDevo

1 week ago 262 111 21 10

🥳🥳🥳

6 days ago 1 0 0 0

Thank you so much, Uri!! :)

1 week ago 0 0 0 0

Congratulations to Max Planck Research Group Leader Can Aztekin and his team on their new paper in @science.org. They have discovered how oxygen-sensing explains why amphibians regenerate limbs and mammals do not.
Read the full press release here: tinyurl.com/bsuwmek6

1 week ago 23 7 1 0

This is amazing work. Congrats to you and the team on these incredible insights. Perfect example of why comparative biology is so important.

1 week ago 4 2 0 0

Thank you!!

1 week ago 0 0 0 0
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Thanks a lot Josh!!

1 week ago 0 0 0 0

Thank you Eve!! :)

1 week ago 1 0 0 0

Thanks a lot Kristian! Hope all is well!!

1 week ago 0 0 0 0

Thank you Aida!! :) 🥳

1 week ago 0 0 0 0
Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...

Check out 2 papers and a related Perspective on tissue regeneration in @science.org this week
Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration | Science www.science.org/doi/10.1126/...

1 week ago 20 11 1 1

Thank you!! :)

1 week ago 0 0 0 0

Thank you, Juliane!!

1 week ago 1 0 0 0
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Thank you so much, Sara!! 🤩 🥳

1 week ago 1 0 0 0

Thank you!! :)

1 week ago 0 0 0 0

Thanks Malcolm!

1 week ago 0 0 0 0

I've always been fascinated by #regeneration;
& I have to say, my friend @canaztekin.bsky.social & his team always deliver…
If anything, I feel like he’s on track to find a way to grow two extra hands to pipette while simultanously writing grants.

Congrats

1 week ago 14 3 1 0

Not #zebrafish per se, but has big implications for the community 🤩

1 week ago 3 1 1 0

Congrats @canaztekin.bsky.social and everyone involved. Beautiful story on that has wide ranging implications. #EvoDevo & #regeneration at its best!

1 week ago 11 1 1 0

Thank you for your kind words, Yasin!! :)

1 week ago 1 0 0 0

Thank you so much! Of course the fish and the frog can be friends! 🥳

1 week ago 1 0 1 0
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Thank you so much, Tugce!! :)

1 week ago 1 0 0 0

Thank you, Kristina! Hope all is well in Vienna!! :)

1 week ago 1 0 0 0

Thank you so much, David!! 🥳

1 week ago 0 0 0 0
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elmo from sesame street is standing in front of a fire ALT: elmo from sesame street is standing in front of a fire

Thank you!!! -all this fire consumes oxygen anyways 😂

1 week ago 2 0 0 0
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"La capacité de régénération n'est pas perdue chez les mammifères, elle est simplement inactive"

"La capacité de régénération n'est pas perdue chez les mammifères, elle est simplement inactive"

1 week ago 3 1 0 1

Thank you, Omaya! You are always so generous with your compliments!

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