Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection - Nature Microbiology A secondary metabolite sensitizes competitor Bacillus subtilis to a wide panel of lytic phages by sequestering iron and preventing the activation of Spo0A.

Microbes weaponizing secondary metabolites to make rivals vulnerable to phage attack 🧪🦠

www.nature.com/articles/s41...

Thrilled to share this new study! A great study to be a part of.

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!

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Orthogonal visualization presents an explanation for chemical gradients in biofilm transport channels. (a) A thin section of a fixed gfp-expressing E. coli JM105 biofilm is presented with arrows at the apical surface indicating regions where transport channels can be viewed sagittally. Thin layers of cells cap the apical surface of the biofilm and enclose the top of transport channels. The inferior portion of the channels remains open to the underlying substrate. A representative view of the section position through the centre of the colony is presented (top left). (b) A schematic proposing nutrient and oxygen gradients through the depth of biofilm transport channels. A thin layer of apical cells seals the top of channels and maintains a strict oxygen gradient, while nutrients and free oxygen can diffuse from the basolateral surface through open channel conduits into the biomass.

🚨 New paper alert! 🚨

We used complementary sensing approaches to study oxygen microenvironments in E. coli biofilm transport channels, which provided a spatial overview of how transport channels maintain chemical gradients in complex communities.

doi.org/10.1099/mic.0.001543

Photo of University of Glasgow attendees at the Microbiology Society Annual Conference, with a blank outline of a person labeled "You!" indicating where you could join.

🚨WE’RE HIRING!🚨 A Research Technician (2y) to join our team & work on exciting projects in bacterial evolution & gene regulation. Come join our growing, supportive Bacteriology Dept @uofglasgow.bsky.social ! 🏴󠁧󠁢󠁳󠁣󠁴󠁿 #MicroBio25 #microsky @microbiologysociety.org Apply by 30th April: tinyurl.com/2z9z9kse

Giving my talk at the Microbiology Society Annual Conference, standing at the podium with my final "take-home" slide on display: Chase that side project, even the simplest experiments can yield novel and publishable results, we still don't know everything about E. coli and RNase P.

What a week! Grateful for the chance to share my recent work on #bacteria, #evolution, and #RNA at my first #MicroBio25 conference. As a new lecturer in the UK, it was an incredible introduction to the vibrant microbiology community here! @microbiologysociety.org

For those of you who approached me at @microbiologysociety.org #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!

University of Glasgow Bacteriologists representing at #Microbio25 @uofgsii.bsky.social @uofgmvls.bsky.social @microbiologysociety.org

New paper from the group - here we show that aurodox prevents shiga toxin mediated damage in a murine model. Interesting changes to the microbiota too. Amazing work by @rebeccamchugh.bsky.social and the group.

Paper here- rdcu.be/efW0K

Annual Conference 2025 31 March - 03 April 2025

Welcome to day two of #Microbio25! Make the most of the events on offer today by viewing the full itinerary - microb.io/Microbio25

It’s #Microbio25 and I will have a poster up today at A055! Come along and chat with me about Shiga toxin producing E. coli and differences in toxin expression levels

Ready for the first talks at @microbiologysociety.org 2025 annual conference.
@samkaytucker.bsky.social
#microbio2025 🦠

Strain-level variation among vaginal Lactobacillus crispatus and Lactobacillus iners as identified by comparative metagenomics - npj Biofilms and Microbiomes npj Biofilms and Microbiomes - Strain-level variation among vaginal Lactobacillus crispatus and Lactobacillus iners as identified by comparative metagenomics

📣Publication alert!
Another great output from @metagymomics.bsky.social for his PhD. Looking at strain level genetic variation within members of the vaginal microbiome. #microsky @pauldcotter.bsky.social @calumwalsh.bsky.social
www.nature.com/articles/s41...

Professor Lilach Sheiner pictured in the lab holding the C.A. Wright medal in an open presentation case.

🏅 | @uofgsii.bsky.social's Professor Lilach Sheiner (@sheinerlab.bsky.social) was recently awarded the prestigious C.A. Wright Medal by the @bspparasitology.bsky.social for outstanding contributions to the discipline.

Congratulations, Professor Sheiner!

🔗 Full story: www.gla.ac.uk/schools/infe...

Looking forward to reading this paper!

🚨 🧬 Updated preprint on the completed BASEL collection - what's new? Some fun with bacterial immunity and a new P22 relative infecting E. coli K-12. A thread 🧵

🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44

A plasmid-chromosome crosstalk in multidrug resistant enterobacteria - Nature Communications The authors describe a new crosstalk between a globally disseminated carbapenem resistance plasmid and clinical enterobacteria clones. This crosstalk provides a fitness advantage to the plasmid-carryi...

Very happy to see this work published! We unveil a plasmid-chromosome crosstalk by showing that pOXA-48 encodes for a regulator that mediates the transcription of an enterobacterial chromosomal operon, resulting in a growth benefit for the plasmid-carrying bacteria!

www.nature.com/articles/s41...

We are pleased to announce that ETOX 2025, the 22nd European Workshop on Bacterial Protein Toxins, will be held in Spain, June 29 - July 3, 2025. Registration opens on January 6. Apply here etox-meetings.org and join us for a great meeting! Please repost

Another great year working in the Roe lab and the bacteriology department.

Happy holidays everyone!

We have created a University of Glasgow Bacteriology starter pack for infection and immunity researchers.

We all share a mutual interest in understanding and reducing bacterial pathogenesis. Have a look at the link below!

@uofgsii.bsky.social
go.bsky.app/CJyjtir

EF-P and its paralog EfpL (YeiP) differentially control translation of proline-containing sequences - Nature Communications EF-P plays an important role in overcoming polyproline sequence-induced stalling in bacteria. Here, the authors show that its paralog, EfpL, can also resolve this type of stalling, and also sense cell...

EfpL (YeiP) -one of the many rescue factors that relieves ribosome stalling at polyproline seq. 🧪 #Ribosome www.nature.com/articles/s41...