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Posts by Linden Parkes

Constructing connectome-based neural networks

Constructing connectome-based neural networks

Really excited to share a new preprint!

๐—›๐—ผ๐˜„ ๐—ฑ๐—ผ ๐—ฏ๐—ฟ๐—ฎ๐—ถ๐—ป๐˜€ ๐˜€๐˜๐—ฎ๐˜† ๐—ฟ๐—ผ๐—ฏ๐˜‚๐˜€๐˜ & ๐—ฒ๐—ณ๐—ณ๐—ถ๐—ฐ๐—ถ๐—ฒ๐—ป๐˜ ๐˜„๐—ต๐—ถ๐—น๐—ฒ ๐—ฏ๐—ฒ๐—ถ๐—ป๐—ด ๐—ถ๐—ป๐—ฐ๐—ฟ๐—ฒ๐—ฑ๐—ถ๐—ฏ๐—น๐˜† ๐˜€๐—ฝ๐—ฎ๐—ฟ๐˜€๐—ฒ? We explore how!
www.biorxiv.org/content/10.6...

We built Connectome-based Neural Networks (CoNNs) using Drosophila wiring (larva&adult) & compared with random networks with same sparsity.

2 weeks ago 48 13 1 1

Our latest publication grapples with how the brain could implement gradient descent by sending learning targets top-down, gating plasticity with dendritic inhibition, and updating synaptic weights with biologically observed learning rules like BTSP.

www.cell.com/cell-reports...

3 weeks ago 92 35 4 5
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Neuroanatomy reflects individual variability in impulsivity in youth - Molecular Psychiatry Molecular Psychiatry - Neuroanatomy reflects individual variability in impulsivity in youth

Our latest work looking at the neuroanatomical basis of impulsivity in youth is out now in Molecular Psychiatry!

4 weeks ago 38 24 2 2
The power of community | Published in Aperture Neuro By Elvisha Dhamala. Looking ahead, our field must continue to prioritize diversity among researchers and commit to studying brain function and dysfunction across varied populations, life stages, and s...

Check out my latest editorial reflecting on OHBM 2025 and emphasizing the power our community has to advance diversity and inclusion in research.

1 month ago 2 3 0 0
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โ€ชEver wondered how GABAergic interneurons shape cognition? The IN-CODE consortium's latest NeuroView article introduces a "population approach", shifting the focus from individual interneurons to cooperative networks. Dive into the future of interneuron research here: doi.org/10.1016/j.ne...

1 month ago 25 12 0 0
how does his brain do it ? #neuroscience #memory #sport Nelson Dellis 6x US memory champion
how does his brain do it ? #neuroscience #memory #sport Nelson Dellis 6x US memory champion YouTube video by Roselyne Chauvin

The 6x US memory champion โ€“ Nelson Dellis โ€“ can memorize a deck of cards in 40 seconds and knows the first 10K digits of pi.
To figure out how, he let us peak inside his brain. Here is what we learned in our precision brain mapping study www.biorxiv.org/content/10.6...

youtube.com/shorts/MryMq...

1 month ago 81 32 5 7
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Cascades and convergence: Dynamic signal flow in a synapse-level brain network Author summary To understand how the brain processes and merges information from our senses, we need more than just a โ€œwiring mapโ€ of its connections; we need to see how signals actually travel throug...

๐ŸšจAnother new one from the lab!

Cascades and convergence: Dynamic signal flow in a synapse-level brain network

We simulate sensory cascades in a bona fide biological neural network.

With Caio Seguin, Maria Grazia Puxeddu, and @misicbata.bsky.social!

journals.plos.org/complexsyste...

1 month ago 22 9 0 0
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I couldn't find a tool to plot different #neuroimaging data in one consistent style, so I made one! Meet yabplot (yet another brain plot) - a #Python package for (sub)cortex & tracts.๐Ÿง 
- Simple API
- Built-in atlases
- Custom atlas support
๐Ÿ”— github.com/teanijarv/ya... (drop a โญ๏ธ!)

1 month ago 58 22 1 0
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We think of white matter as the highways of the brain. But when we followed development along those highways, we were surprised. The journey is more complex than we thought. My final PhD paper, โ€œTwo Axes of White Matter Developmentโ€, is now out in @natcomms.nature.com! ๐Ÿ›ฃ๏ธ๐Ÿง โœจ
๐Ÿ”— bit.ly/wm2axes

1 month ago 105 47 2 4
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Check out our latest led by @richardfbetzel.bsky.social !! ๐Ÿ‘€โšก๐Ÿงฒ

1 month ago 7 0 0 0
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Exploring the Role of the Rich Club in Network Control of Neurocognitive States Using a network control theoretical framework, we found that the brain's rich club does not optimally control dynamics of the brain. Instead, size-matched sets of random peripheral regions had a sign...

๐Ÿšจ New paper from @apodschun.bsky.social (with Sebastian Markett, Urs Braun, and myself)

Exploring the Role of the Rich Club in Network Control of Neurocognitive States

onlinelibrary.wiley.com/doi/10.1002/...

1 month ago 21 10 0 0

The revised version of our paper on the impact of top-down feedback is now out @elife.bsky.social:

doi.org/10.7554/eLif...

tl;dr: we show that using human-brain-like feedback/anatomy in a deep RNN leads to human-like visual biases!

This work was led by @tmshbr.bsky.social

#NeuroAI ๐Ÿง ๐Ÿ“ˆ ๐Ÿงช

2 months ago 65 18 0 0
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Computer model predicts aspects of cognitive performance The Allen Human Brain Atlas helped researchers design a model that looked at โ€œintrinsic neural timescalesโ€

Intelligence is not just about having "strong" brain connections. Itโ€™s also about how efficiently the brain coordinates processing speed across regions.

@lindenmp.bsky.social and @jason-z-kim.bsky.social share what their computer model is revealing about cognitive power: https://bit.ly/3LQuoxT

2 months ago 13 3 0 0
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๐—ง๐—ต๐—ฟ๐—ฒ๐—ฎ๐˜/๐—ฒ๐—บ๐—ผ๐˜๐—ถ๐—ผ๐—ป ๐—ถ๐˜€ ๐—ฑ๐˜†๐—ป๐—ฎ๐—บ๐—ถ๐—ฐ
So we model the dynamics.
Version of record of our paper is available.
#neuroskyence
elifesciences.org/articles/102...

2 months ago 60 12 2 1
The biological role of local and global fMRI BOLD signal variability in multiscale human brain organization - Nature Communications Baracchini et al. reveal that temporal variability in fMRI brain signals encodes biologically meaningful information across spatial and temporal scales, highlighting its role in healthy brain function...

Now in press one of my last PhD projects! We traced the neurobiological profile of fMRI BOLD signal variability, a measure that has been related to age, behaviour, disease status, but had not yet been fully contextualised within the brain's multiscale architecture. www.nature.com/articles/s41...

2 months ago 38 14 2 1
Nine subcortical/cerebellar atlases included in the subcortex_visualization Python package (and subcortexVisualizationR package in R). The atlases are depicted in two-dimensional vector graphic format.

Nine subcortical/cerebellar atlases included in the subcortex_visualization Python package (and subcortexVisualizationR package in R). The atlases are depicted in two-dimensional vector graphic format.

The extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that Iโ€™ve graduated ๐Ÿค  This figure shows the 9 atlases included (and counting)!

Preprint: www.biorxiv.org/content/10.6...
Website: anniegbryant.github.io/subcortex_vi...

2 months ago 115 46 3 6
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Thanks to the Allen Institute for the write-up of our recent work! ๐Ÿ‘

Paper is here: www.nature.com/articles/s41...

2 months ago 22 9 0 0
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Our latest preprint on how regional cellular, molecular, and other forms of heterogeneity shape macroscopic wave dynamics is now out:
www.biorxiv.org/content/10.6...

For a full thread, see:
x.com/_victorbarne...

2 months ago 31 16 0 0

So happy to see this new, growing open data resource out -- all credit to the amazing @juliettebrook.bsky.social + @tsalo.bsky.social + a superb team!!!!

NOTE: @juliettebrook.bsky.social is currently applying to clinical psych PhD programs -- great opportunity to recruit a โญTOTAL โญ STAR โญ

2 months ago 8 5 0 0
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Wanna compare dynamics across neural data, RNNs, or dynamical systems? We got a fast and furious method๐ŸŽ๏ธ
The 1st preprint of my PhD ๐Ÿฅณ fast dynamical similarity analysis (fastDSA):
๐Ÿ“œ: arxiv.org/abs/2511.22828
๐Ÿ’ป: github.com/CMC-lab/fast...
Iโ€™ll be @cosynemeeting.bsky.social - happy to chat ๐Ÿ˜‰

3 months ago 114 35 1 4
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Study: Long Breaks Tied to Dip in Cognitive Test Performance - UConn Today A joint UConn - University of Minnesota research study concludes that there may be some reality to the "summer slide" of dips in test scores follo ...

Finding it tough to get back in the swing of things after vacation? You're not alone! Our study found that U.S. adults show lowest performance on cognitive tasks like executive functioning after winter break
Thanks @uconn.bsky.social for this highlight!
tinyurl.com/4dmssj5m
#PsychSciSky #AcademicSky

3 months ago 8 2 2 0

Pitty it has to disappear back into the file drawer come semester start! ๐Ÿ˜…

3 months ago 0 0 1 0
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BHI December Monthly Newsletter Email from Rutgers Brain Health Institute Stay up-to-date with the latest faculty achievements, upcoming events, activities, and opportunities and more โ€Š As we come to the end of 2025, BHI would like

๐Ÿ“ฉCheck out the Rutgers Brain Health Institute (BHI) December Monthly Newsletter. Stay up-to-date with our latest faculty achievements, upcoming events, activities, opportunities, and more.
conta.cc/3MPkexA
@rutgersupress.bsky.social #RutgersBHI #neuroscience #brainhealth #mentalhealth #BHINewsletter

3 months ago 1 1 0 0
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๐—–๐—ฎ๐—ป ๐˜„๐—ฒ ๐˜€๐˜๐˜‚๐—ฑ๐˜† ๐—ฏ๐—ฟ๐—ฎ๐—ถ๐—ป ๐—ฑ๐˜†๐—ป๐—ฎ๐—บ๐—ถ๐—ฐ๐˜€ ๐˜„๐—ถ๐˜๐—ต ๐—ณ๐— ๐—ฅ๐—œ?
We employed Switching Linear Dynamical Systems to investigate the dynamics of resting-state networks
They are dynamic, not static!
Work with Xiaoyu Zhao with lots of new methods.
Thread.
#neuroskyence
www.biorxiv.org/content/10.6...

4 months ago 61 17 1 0

Our paper on the โ˜€๏ธ "summer slide" ๐Ÿ› is out now @pnas.org!
www.pnas.org/doi/10.1073/...
Summer slide is a replicable phenomenon across diverse datasets that's more than "forgetting" school material in vacation months, but effects of socioeconomic inequality are โžก๏ธ 7x bigger! โฌ…๏ธ
#PsychSciSky #DevPsy
๐Ÿงต๐Ÿ‘‡

4 months ago 124 51 2 6
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๐Ÿšจnew work with the dream team @danakarca.bsky.social @loopyluppi.bsky.social @fatemehhadaeghi.bsky.social @stuartoldham.bsky.social @duncanastle.bsky.social
We use game theory and show the brain is not optimally wired for communication and thereโ€™s more to its story:
www.biorxiv.org/content/10.6...

4 months ago 61 26 4 0
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The dual interpretation of edge time series: Time-varying connectivity versus statistical interaction Functional connectivity (FC) is frequently operationalized as a correlation. Many studies have examined changes in correlation networks across time, claiming to link time-varying fluctuations to ongoi...

Just provisionally accepted -- preprint updated | The dual interpretation of edge time series: Time-varying connectivity versus statistical interaction | www.biorxiv.org/content/10.1...

4 months ago 30 13 1 1
Job Search

Come and join our team! We are looking for a Research Officer to help with recruitment and assessment on a large-scale human brain imaging study:

careers.pageuppeople.com/513/cw/en/jo...

4 months ago 11 12 0 0
OHBM 2025 | Oral Session | Stuart Oldham | Only a matter of time: developmental heterochronicity cโ€ฆ
OHBM 2025 | Oral Session | Stuart Oldham | Only a matter of time: developmental heterochronicity cโ€ฆ YouTube video by Organization for Human Brain Mapping

My very normal, by the book presentation from this years OHBM is now available. So if you weren't at OHBM, were there but happened to miss it, or if you did see it and just want to relive it all over again, here is your chance :)

I'm quite fond of this one.

www.youtube.com/watch?v=lP86...

4 months ago 17 6 2 0

Woohoo! So good to see @ahmadbeyh.bsky.social winning the Best Poster Award at this year's Rutgers BHI Symposium! ๐Ÿค˜๐Ÿ”ฅ๐Ÿ‘

4 months ago 5 1 0 0