SGLT2 Inhibitors Associated With Improved Kidney Function in Lithium‐Treated Patients With Mood Disorders: A Real‐World Historical Cohort Study Introduction Sodium-glucose cotransporter-2 inhibitors (SGLT2i), initially developed for type 2 diabetes, have shown promise in improving renal outcomes in patients with and without diabetes. Howeve...

Excited about our latest publication in Bipolar Disorders! 🎉 SGLT2 inhibitors were associated with improved kidney function trajectories in lithium-treated patients 💊📈
Grateful to all collaborators!
🔗 onlinelibrary.wiley.com/doi/epdf/10....

Our machine learning competition on forecasting depression is online! We'd love for as many people as possible to participate. Please share in your respective networks — thank you :).

www.staff.universiteitleiden.nl/announcement...

📢 Our new systematic review & meta-analysis is out! Across 50 studies, we examined the prevalence of dermatologic side effects 📊 of mood stabilizers 💊 in bipolar disorder. 🔍 Full text: doi.org/10.1016/j.jp...

3/ I'm grateful to my close collaborator Alessandro Miola, our dedicated team at @mayoclinic.org Psychiatry, and my mentors Aysegul Ozerdem and Mark Frye. I also want to thank my mentor in residency Alp Ucok, who taught me the importance of early intervention and inspired my passion. 🌟

2/ Our findings support a transdiagnostic framework for more precise, tailored early interventions in mental health—guided by each subgroup’s unique trajectory. 🎯🧠✨

1/ Based on antecedent psychopathology—including symptoms, psychiatric diagnoses, substance use, and medication exposure—we identified three classes:
🧩 Neurodevelopmental
🌧️ Depressive-Anxious
🛡️ Minimal Psychiatric Morbidity

Are there unique pathways leading to a first episode of mania or psychosis? 🔍 Using latent class analysis, we identified 3 distinct antecedent trajectories. 📄 PDF: onlinelibrary.wiley.com/share/author...
🔗 Link: doi.org/10.1111/acps... 👇

Does mental health shape cancer outcomes? 🧠🎀 We studied how bipolar disorder affects breast cancer diagnosis & outcomes, focusing on genetic risk 🧬 and lifestyle 🏃‍♀️🍷🍔. Grateful to lead this effort and work with such an incredible team! 🔗 authors.elsevier.com/c/1lIHJ_3mNQ...

Seasonality Linked to Different Bipolar Features Subtypes of seasonality are associated with varying characteristics of bipolar disorder and with response to treatments such as lithium, a new study suggests.

Thrilled to share our findings at #APAAM2025 in LA!
Seasonality Linked to Different Bipolar Features and Treatment Response 🌸☀️🍂❄️
Presented on behalf of Siralp Bostan, MD — with tremendous contributions from Lindsay Melhuish, PhD. Great team effort!
📰 www.medscape.com/viewarticle/...

Our commentary/mini review on Lithium and Kidney Disease (doi.org/10.1016/j.ma...) is just published in Mayo Clinic Proceedings! We discuss key risk factors🩺, controversies📊, and challenges surrounding discontinuing lithium⚖️.
A glance at 📺: youtu.be/aiUHRfGNn50?...