Manipulating Engram Histone Acetylation Alters Memory Consolidation The epigenome provides the brain with a nucleus-templated form of plasticity that is of fundamental importance for learning and memory. Of the various types of epigenetic modifications, elevations in....

🚨 @lisawatt.bsky.social 's paper is out! We uncovered an epigenetic ‘swing’ that tunes how neuronal ensembles capture memories in the brain 🧬🛝🧠. A project that I co-supervised with @graeffjohannes.bsky.social. Kudos to all authors! onlinelibrary.wiley.com/doi/10.1002/...

L' EPFL démontre quʹon peut moduler la mémoire chez la souris | RTS Une équipe de l’EPFL montre qu’il est possible de modifier la mémoire chez la souris en intervenant sur un seul gène, Arc, actif dans les neurones qui stockent nos souvenirs, les cellules d’engramme. ...

I had the pleasure of being interviewed on RTS today about my recently published research - in my most adventurous French yet! Merci RTS for hosting! 🧬🧠📻👇🏾www.rts.ch/audio-podcast/2025/audio...

Unlocking the epigenetic secrets of memory - Nature Genetics The epigenetic underpinnings of memory are still poorly understood. A study provides a causal link between the epigenetic dynamics of a single genomic locus in engram cells and memory formation, achie...

Thrilled to see such a compelling and thoughtful commentary on our freshly published paper. By @mpi-psychiatry.bsky.social

www.nature.com/articles/s41...

Huge congrats to all authors and thank you @drawimpacts.bsky.social for the cover art illustrating how epigenetic modifications act as molecular memory aids!

Cell-type- and locus-specific epigenetic editing of memory expression - Nature Genetics CRISPR-based epigenetic editing is used in a cell-type-specific, locus-restricted and temporally controllable manner in the adult mouse brain to modulate memory expression.

🚨The paper from my postdoc in @graeffjohannes.bsky.social’s lab at @epfl-brainmind.bsky.social is out! We show that memories can be switched on and off by simply changing the « packaging » of DNA in neurons through epigenetic editing. www.nature.com/articles/s41...