Metabolic costs and trade-offs of hypermetabolism in human motor neurons with ATP synthase deficiency - Communications Biology Hypermetabolism results in the redistribution of acetyl-CoA usage, reduced histone acetylation, and potential vulnerabilities of motor neurons via altered maintenance of acetylcholine

🔎 What are the consequences of hypermetabolism in human motor neurons?

Our new study from the @htyynismaa.bsky.social lab is out!

Using human iPSC-derived motor neurons, we show that increased energy demand drives key metabolic trade-offs.

🔗 www.nature.com/articles/s42...

Thanks for creating the list. I would really appreciate it if you could add me too! :)

Thanks for creating the list. I would really appreciate it if you could add me too!

Hola Juan, thanks for creating the list! I would really appreciate it if you could add me too!