Simple, scalable, and ultrasensitive tip-based identification of protease substrates Proteases are in the center of many diseases, and consequently, proteases and their substrates are important drug targets as represented by an estimat…

I think ChaFRADIC/ChaFRATIP would have reasonable sample handling, and should work with short LC-MS gradients to keep a high throughput. If you want to do DIA with the protocol perhaps heavy dimethyl label opposed to an isobaric tag? www.sciencedirect.com/science/arti...