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Posts by Desdemona Fricker

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Wanna do neuroscience in Paris but can't find interesting lab?

Want to come do a sabbatical but don't know who to collaborate?

Check this webpage aggregating ~all the neuroscience labs (+200) in Paris.

⚠️only the information of 'verified' profiles is reliable⚠️

Please retweet 🙏

parisneuro.fr

2 weeks ago 126 71 2 2
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Dorsoventral hippocampus neural assemblies reactivate during sleep following an aversive experience - Nature Neuroscience Synchronization of sharp-wave ripples across the dorsoventral hippocampus during sleep supports coordinated reactivation that represents negative experiences more faithfully than positive ones.

Thrilled to see our paper published! I’m deeply grateful to the amazing @ggirardeau.bsky.social for trusting me to develop and carry it out. Many thanks as well to @azulsilva.bsky.social , @belalima-paiva.bsky.social and Eleonore for driving this work forward together.
www.nature.com/articles/s41...

2 weeks ago 11 5 1 0

🧠 Looking forward to Mark Brandon’s visit ! His work on Head Direction coding changed how we think of the neural compass: Network gain maintains a memory trace of previous experience. 🗓️ Join us for his seminar on April 3rd at 11h30 📍45 rue des Saints-Pères, Paris

4 weeks ago 8 5 0 0
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Hi BlueSky — I’m bringing over an old SciTwitter thread series exploring how beautifully the vestibular system works from a systems and computational neuroscience perspective.

Chapter 1 coming shortly! I’ll keep all chapters threaded below.

1 month ago 17 4 1 1
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'The postsubiculum as a head-direction cortex'

by Adrian Duszkiewicz, Desdemona Fricker, Andrea Burgalossi & Adrien Peyrache

@adrian-du.bsky.social @desdemonafricker.bsky.social @apeyrache.bsky.social

www.cell.com/trends/neuro...

2 months ago 23 4 0 0
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New paper alert! 🚨

We found that the brain's compass is remarkably stable at two scales

1️⃣ the system maintains its internal organization for weeks
2️⃣ It "remembers" its orientation for weeks, even after a single visit

This may be key to how the brain aligns its other maps.

Paper: rdcu.be/e3waP

2 months ago 199 69 5 7
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La @semaineducerveau.bsky.social arrive bientôt au SPPIN !

Nous avons le plaisir d’accueillir une conférence suivie d’une visite du laboratoire par @uligraupner.bsky.social dédié aux approches optogénétiques pour comprendre les circuits neuronaux et le comportement.

2 months ago 7 4 1 0

We had a lot of fun doing these experiments! Theta sweeps in MEC and internal direction signals in parasubiculum track moving objects during pursuit and reverse during backward movement. Simultaneously recorded HD cells in other areas remain locked to head direction across behaviors:

2 months ago 33 14 1 0
Paris NeuroCourse | Optical Imaging and Electrophysiological Recording in Neuroscience

If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd
parisneuro.ovh

2 months ago 15 14 3 0

Active locomotion predictively rescues head direction attractor dynamics in head-fixed mice www.biorxiv.org/content/10.64898/2026.01...

3 months ago 5 2 0 0
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Fantastic work!

3 months ago 5 1 0 0

I’m very happy to share the latest from my lab published in @Nature

Hippocampal neurons that initially encode reward shift their tuning over the course of days to precede or predict reward.

Full text here:
rdcu.be/eY5nh

3 months ago 105 32 2 2
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Plastic landmark anchoring in zebrafish compass neurons Nature - Using two-photon microscopy with a panoramic virtual reality setup, how head direction cells in larval zebrafish integrate visual landmarks and optic flow to track orientation is revealed.

1/6: New publication from the lab: “Plastic landmark anchoring in zebrafish compass neurons” by Ryosuke Tanaka (@ryosuketanaka.bsky.social) and Ruben is available here:
rdcu.be/eX1L4

3 months ago 48 23 1 1
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Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex Nonlinear dendritic integration in single presubicular neurons provides a mechanism for combining vestibular-based head-direction signals and visual landmark signals to anchor the brain’s internal com...

Coincidence of thalamic HD signal and retrosplenial visual input is detected in the Presubiculum! 🎯 This may be the neuronal basis for landmark anchoring of the HD signal. Pleased to announce the VOR is now available elifesciences.org/articles/92443 Congrats first author Louis Richevaux 🙌

3 months ago 36 12 1 2
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1/n: A new collaborative preprint from the lab to start the year: "A multi-ring shifter network computes head direction in zebrafish" together with Siyuan Mei, Martin Stemmler and Andreas Herz from the LMU, Munich.

3 months ago 58 26 1 3
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Characterizing neuronal population geometry with AI equation discovery The visual cortex contains millions of neurons, whose combined activity forms a population code representing visual stimuli. There is, however, a discrepancy between our understanding of this code at ...

1. New preprint resolving a conundrum in systems neuroscience with an AI scientist, and humans Reilly Tilbury, Dabin Kwon, @haydari.bsky.social, @jacobmratliff.bsky.social, @bio-emergent.bsky.social, @carandinilab.net, @kevinjmiller.bsky.social, @neurokim.bsky.social
www.biorxiv.org/content/10.1...

5 months ago 94 26 1 8
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📢 We are organising the Senses in Motion conference for the third time, and we are now accepting abstracts for posters or talks.

Deadline for abstracts: 19 December
Conference dates: 18–21 May 2026
Location: Harnack House, Berlin

Register via this page👇
sensesinmotion.org

#neuroskyence #neurosky

5 months ago 20 9 0 0
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Grid cells accurately track movement during path integration-based navigation despite switching reference frames - Nature Neuroscience Grid cells do not maintain a stable pattern during a self-motion-based task, but track animal movement in multiple local reference frames and reanchor to task-relevant objects, thus estimating local r...

No GPS in the head? Path integration by entorhinal grid cells without the grid pattern. Interesting paper from Heidelberg. www.nature.com/articles/s41...

5 months ago 6 2 0 0
Bat Island: The New Era of Science
Bat Island: The New Era of Science YouTube video by Weizmann Institute of Science

Neuroscience projects last several years, and you are usually a bit jaded by the time you wrap it up. Not this one– spending several months on an island in the middle of nowhere, away from all the craziness of the world reminds you how beautiful the world really is.

www.youtube.com/watch?v=46sv...

6 months ago 60 18 1 2
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The postsubiculum as a head-direction cortex The organisation of thalamocortical networks follows a conserved structure. Traditionally, these are divided into primary sensory systems that receive…

Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)

6 months ago 46 18 2 1
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🚨new paper: the head-direction circuit as a model of primary thalamocortical system. Check this out 👇

kudos to @adrian-du.bsky.social for the huge amount of work put into this opinion piece, starting with the beautiful figures comparing the different thalamocortical systems 🤩

6 months ago 33 9 0 0
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Thanks to the Capitainerie de l’Isle and to Nathalie for hosting our exhibit ✨

6 months ago 5 2 0 0
Travel Grants — COSYNE Apply for COSYNE 2026 Travel Grants to support your participation in Lisbon and Cascais, Portugal. Grants are available for students, postdocs, and PIs, including programs for Childcare, Presenters, N...

Travel awards are available for undergraduate students looking to attend #Cosyne25! The application is short, and the deadline is Nov 12. @cosynemeeting.bsky.social

Application: shorturl.at/6NEyk

More info: www.cosyne.org/travel-grants

(1/2)

6 months ago 30 24 1 2
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Dear #ParisNeuroscience community, here is the schedule of the upcoming 'Neural Networking Night' season !

7 months ago 6 7 0 1

2/6

Recording in decision-making regions from many neurons at once revealed the neurons' collective evolution as decisions were made

Each decision had two phases: first, neural state was sensitive to sensory inputs; then, trajectories in neural state space turned and became insensitive to inputs.

7 months ago 3 1 1 0
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Thanks to the Capitainerie de l’Isle and to Nathalie for hosting our exhibit ✨

6 months ago 5 2 0 0
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Transitions in dynamical regime and neural mode during perceptual decisions - Nature Simultaneous recordings were made of hundreds of neurons in the rat frontal cortex and striatum, showing that decision commitment involves a rapid, coordinated transition in dynamical regime and neura...

How does the brain decide? 🧠

Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.

After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.

rdcu.be/eGUrv

7 months ago 250 97 13 2
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Coherent dynamics of thalamic head-direction neurons irrespective of input While the thalamus is known to relay and modulate sensory signals to the cortex, whether it also participates in active computation and intrinsic signal generation remains unresolved. The anterodorsal...

🚨New preprint alert!

The thalamus has long been seen as a relay of sensory signals to cortex.
But could it also generate its own structured activity?
Our study explores this question in the head-direction (HD) system.

Some explanation 🧵👇 1/13

www.biorxiv.org/content/10.1...

7 months ago 93 25 2 1

Voir Montrer Regarder 👀
Observer Mesurer Vérifier #SciArt
If you are in Paris in September check out our exhibit “Regards Croisés”: Come for the Art, stay for the Science ! This scientific outreach event is supported by @c-brains.bsky.social, @sppin-cnrs.bsky.social and the Capitainerie de l’Isle.

8 months ago 10 4 2 0
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Granularity of thalamic head direction cells Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...

*New preprint from the lab* – “Granularity of thalamic head direction cells”
doi.org/10.1101/2025...
🧠📈 🧪
1/11

7 months ago 26 10 2 2