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Posts by Fitz-James Lab

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Join IGH as Group Leader - IGH The Institute of Human Genetics invites applications for a Principal Investigator position in its main research areas. Read more...

We are looking for a new group leader to join the IGH (Montpellier, France). I can’t wait to meet my future colleague! Apply :-) More infos here: igh.cnrs.fr/join-igh-as-...

1 month ago 46 60 0 1
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We are hiring POSTDOC now!🚨please repost! Fully-funded 5-year position 👩🏻‍🔬👨‍🔬🧬Looking forward to your application!✉️

4 weeks ago 53 49 0 0
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We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).

1 month ago 107 125 1 4
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Postdocs at Center for Gene Expression in Department of Cellular and Molecular Medicine - Copenhagen, Hovedstaden (DK) job with University of Copenhagen | 12849488 We are looking for 2 or more highly motivated postdocs interested in ribosome biology, 3D chromatin organisation, or regulation of protein turnove...

We are looking for a Postdoc at the Center for Gene Expression in Copenhagen. Deadline for applications is the 11th of January. If you are interested in 3D chromatin, SMC complexes, and super-resolution microscopy, join us. www.nature.com/naturecareer...

3 months ago 21 25 0 2
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Heterochromatin boundaries maintain centromere position, size and number - Nature Structural & Molecular Biology Carty et al. identify the H3K9 methyltransferases that restrict the size and position of the centromere protein A chromatin domain, maintaining functional centromeres.

Very proud to have our latest work now online in
@natsmb.nature.com. A wonderful team effort across the centromere community, across @jansenlab.bsky.social @naltemose.bsky.social @dfachinetti.bsky.social and Giunta labs. Happy reading! 1/4

www.nature.com/articles/s41...

4 months ago 51 16 2 1
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WE ARE RECRUITING PHD STUDENTS!!!

We have three(!) funded PhD studentships advertising presently. If any of these are of interest, please reach out! Thread below with links to more information on each project.

#Drosophila #Evolution #Immunity #SelfishGene #Aphids

Thread with links below 🧵 1/4

5 months ago 40 48 2 0
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It’s been a big month for the lab! We’ve gone from just me to six in as many weeks. I’m so excited to embark on this new chapter with these wonderful people, and I’m looking forward to the exciting science 🧪we’ll be doing together in the new Life and Mind Building @biology.ox.ac.uk
#epigenetics

6 months ago 19 1 0 0
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Excited to be presenting my work today at @biochemsoc.bsky.social event Transcription and Chromatin UK!

7 months ago 5 2 0 0

Would love to be added as well please!

8 months ago 1 0 0 0
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Last day of #SMBE2025 in Beijing!
It was a real pleasure to talk about epimutation on Tuesday and to get to know lots of new researchers and their exciting work!

8 months ago 9 2 0 0

Traveling to Beijing for @official-smbe.bsky.social #SMBE 2025. I have both a talk and a poster on Tuesday on different aspects of epigenetic inheritance. Stop by if you’re there!

9 months ago 5 1 1 0
SIDB

🚨Fantastic PhD opportunity for Autumn 2025 with our colleague Rebekah Tillotson @uoe-igc.bsky.social, asking whether ATRX syndrome is treatable:
sidb.org.uk/phds/tillots...
Please share 🙏
#epigenetics #raregeneticdisease #chromatinopathies

9 months ago 7 5 0 0
Transcription and Chromatin UK
Manchester, UK
17-19 September 2025
Earlybird deadline: 17 July 2025

Transcription and Chromatin UK Manchester, UK 17-19 September 2025 Earlybird deadline: 17 July 2025

Taking place on 17-19 September 2025, Transcription and Chromatin UK will showcase cutting-edge research and is a ‘mustattend’ for anyone within the transcription and epigenetics community🧪. Register now: www.eventsforce.net/biochemsoc/2...

9 months ago 22 11 0 6

Postdoc positions open in my lab (Francis Crick Institute) to study

1. initiation of DNA replication.

2. chromatin replication/epigenetic inheritance.

Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.

Deadline 3 August 2025.

crick.wd3.myworkdayjobs.com/External/job...

10 months ago 78 80 1 2
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Great opportunity in a fun lab / cool city!

10 months ago 1 0 0 0
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Transparent peer review to be extended to all of Nature’s research papers From today, all new submissions to Nature that are published will be accompanied by referees’ reports and author responses — to illuminate the process of producing rigorous science.

From today, every paper submitted to Nature -if published - will be accompanied by peer reviewers comments & authors rebuttal.

We started the trial in 2020; we now want to open up the review process & showcase its role in shaping & improving papers
🧪 #AcademicSky

www.nature.com/articles/d41...

10 months ago 217 68 8 11
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Clarifying the public misrepresentation of transgenerational epigenetic inheritance - Theoretical Medicine and Bioethics Theoretical Medicine and Bioethics -

A nice short reminder to be wary of the press overstating scientific claims

link.springer.com/article/10.1...

10 months ago 4 1 0 0
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🚨Job Alert🚨

We are looking for a technician to join us in Oxford @biology.ox.ac.uk to study epigenetics and vibration-sensing:

my.corehr.com/pls/uoxrecru...

The work will be varied:
Arthropod culture 🕷️🪰
Lab work (DNA/RNA extraction, sequencing library preparation…)

Apply by Mon 23 June
🧪

10 months ago 2 4 0 0
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Experimental embryology postdoc available in my lab at the @biology.ox.ac.uk @ox.ac.uk working on the evolution of vertebral counts. Reach out if you’re passionate about EvoDevo, enjoy lab work and microscopy and are into or could get into cichlid fishes. Deadline on the 16th June. Please share!

11 months ago 64 66 4 5

Very cool paper combining two of my favourite things: phylogeny and genome organisation

11 months ago 3 0 0 0
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Fly Open access research on Drosophila developmental/evolutionary biology, organogenesis, neurobiology, circadian rhythms, learning & memory, sex determination

Fly journal is now on BlueSky! The world’s only academic journal dedicated to research on Drosophila & cognate insects. A fully open-access journal that combines rapid publication with high standards of peer-review. For further info and how to submit your work, see the link.

1 year ago 13 14 0 4
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Our new review in @cp-trendscellbio.bsky.social is now online! We discuss the connection between the epigenome, 3D genome folding, gene expression and cellular memory, specifically in loop extrusion-independent contexts.

1 year ago 14 6 1 0
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Postdoctoral Research Associate at University of Oxford Discover Postdoctoral Research Associate jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.

TWO postdoc positions in Computational Microbiology and/or biochemistry. Join our interdisciplinary group in the new Life and Mind Building @OxfordBiology, @UniofOxford, @IneosOxford
Please apply and share this post:
www.jobs.ac.uk/job/DMP641/p...

1 year ago 12 31 0 1
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Hello World! Are you passionate about epigenomics and evolution 🧪🧬🐭🐵 ? Are you looking for a postdoc in a stimulating and inclusive environment ? Look no further... We are seeking creative postdocs for our ERC project EvoEpi @igred.fr ! 👇Details👇
tinyurl.com/PostdocEvoEp...
Repost are appreciated

1 year ago 53 55 2 4

Something to ponder when considering which journal to submit to. Society owned journals are an important source of income for the community.

1 year ago 7 2 0 0

10/10 Very happy to have this paper out and for the wonderful work done with Peter and our students Poppy and Chris!

1 year ago 0 0 0 0

9/10 While we can’t fully explain this effect, this downregulation of Pho, with potential downstream effects on Polycomb targets, may be something to keep in mind when using Sb as a marker in future.

1 year ago 0 0 1 0

8/10 In following up on this unexpected result, we found that mutation of Sb has an effect on expression of Pho, a recruiter of the PRC2 complex responsible for depositing H3K27me3.

1 year ago 0 0 1 0

7/10 As controls for our sRNA pathway mutants we used some well-known marker mutations on the same chromosome. One of these, mutation in the gene Stubble (Sb) which is well-known to Drosophila enthusiasts, had a clear effect on eye colour, making it more red.

1 year ago 0 0 1 0
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6/10 Next, we tested an array of mutants in sRNA pathways. Again, we found no effect of the mutations on eye colour, arguing against a role for sRNAs in eye colour. However, a surprising result involving one of our controls jumped out at us…

1 year ago 0 0 1 0