Yin and yang of tumor-associated macrophages Nature Immunology - Our work reveals functional heterogeneity among interstitial macrophages, showing that distinct chemokine programs determine immune cell positioning and interactions within lung...

Research briefing for our new tumor-associated macrophage paper 👇
www.nature.com/articles/s41...
rdcu.be/faeRM

$2.45 billion NIH grant cuts and ~2300 terminated active research grants were DOGE'd in early 2025
Who were most affected?
www.pnas.org/doi/full/10....
Early career and women researchers

Macrophage lineage and spatial compartmentalization govern tumor immunity @natimmunol.nature.com @claudjak.bsky.social @xinli0419.bsky.social
www.nature.com/articles/s41...

Chemokine-defined macrophage niches establish spatial organization of tumor immunity Nature Immunology - Jakubzick and colleagues show that the tumor microenvironment is shaped by opposing programs in tissue-resident CD206hi and CD206lo interstitial macrophages and Ly6c2+Fn1+Vcan+...

Excited to share our work @springernature.com Building on our work defining TRMacs heterogeneity, we show that distinct chemokine+ IM subsets and recruited TAM niches shape pro- and anti-tumor immunity within to the TME, while Ag+ moDCs trafficking to LNs dampen DC-based neoAg vaccine

rdcu.be/e9uZu

Tor D. Wager (@torwager.bsky.social) of Dartmouth College is the recipient of a 2026 Atkinson Prize in Psychological and Cognitive Sciences! He is being honored for pioneering research revealing how the brain shapes pain, emotion, and belief. Read more: www.nasonline.org/award/atkins... #NASaward

Claudia Jakubzick opened Day 2 of the AAI Advanced Course in Immunology with a lecture on “Myeloid Cells in Immune Responses.” Describing how macrophage gene expression and function vary by the tissue in which they reside, and how monocytes influence diverse immune processes.

Check out our new preprint www.researchsquare.com/article/rs-6...

check out our new preprint www.researchsquare.com/article/rs-6...

What 231B is 231,000,000,000.00 (missing 3 zeros) and it 50 million of 231B is 0.02%

Special shout out to recent grad Dr. Xin Li (@xinli0419.bsky.social) from the Jakubzick (@claudjak.bsky.social) Lab who was awarded the 2025 John W. Strohbehn Medal for Excellence in Biomedical Research!! 🤩
guarinigrad.dartmouth.edu/blog/2025/06...

Great piece on @stanford-chemh.bsky.social Institute Scholar @stanleyqilab.bsky.social’s work toward curing diseases with genome editing innovations #ResearchMatters

Switzerland🇨🇭 is an associated country and provides an excellent environment for research! This is a great opportunity if you’re ready for a move

Carl Sagan on sensible military spending and climate change.

Payal it was so fun to be there!!

Heterogeneous human AM subsets have counterparts in mice! Nice work from @claudjak.bsky.social lab

Check out this new podcast from ATS Journals and look for new ones each Thursday!