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Posts by Michelangelo Lassandro

The Biochemical Society 2027 Early Career Research Award presented to Dr Helen Foster from University of Leeds, UK, with award logo and photo.

The Biochemical Society 2027 Early Career Research Award presented to Dr Helen Foster from University of Leeds, UK, with award logo and photo.

Utilising in situ structural biology to uncover fundamental mechanisms of cytoskeletal regulation, we're excited to present Helen Foster with an Early Career Research Award in 2027! Helen's research on immune cell cytoskeletal remodeling could open new frontiers in molecular immunology.

1 week ago 12 4 0 1

📢 First preprint from the Casañal Lab!

Excited to share our work on human NSUN2, done together with the brilliant @ecleroy.bsky.social.

Using #CryoEM, we capture the dramatic structural rearrangement of tRNA as it flips a cytidine into the NSUN2 catalytic pocket for m⁵C modification.

Take a look👇

1 month ago 19 8 0 0

Very happy to say that our work on how axonemes are generated is now available on bioRxiv: www.biorxiv.org/content/10.6... - if you’ve ever wondered how the incredibly beautiful, complex structures within motile #cilia are constructed then this is for you!

2 months ago 85 29 8 3
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🥳Today at HT, we took the time to celebrate one another, recognising colleagues who have stood out for their contributions or positive attitude.

👏Congratulations to the winners: Roberto Zigiotto (Above & Beyond Award) and @giovannimaltinti.bsky.social (Good Vibes Award)!

1 year ago 2 1 0 0
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Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters - Nature Communications The snRNA Activating Protein Complex (SNAPc) mediates snRNA transcription by RNA Pol II and III. Here, the authors have used cryo-EM to resolve the structure of the SNAPc-bound RNA Pol III pre-initiat...

Excited to share the (hard) work of @zawarshah.bsky.social in its final form: www.nature.com/articles/s41...

A lot of insights into RNA Polymerase selectivity at snRNAs promoters !! As these promoters are often used for heterologous expression of RNAs (ie guide RNAs), you better know how they work

1 year ago 52 19 4 2

JOB ALERT!!! The National Facility for Structural Biology at @humantechnopole.bsky.social is HIRING!! BlueSky-less Andrea Graziadei is looking for a technician to join his Unit and push #structuralproteomics to new, uncharted territories!! 1/3

1 year ago 9 11 1 1
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The intraflagellar transport cycle - Nature Reviews Molecular Cell Biology Intraflagellar transport (IFT) ensures delivery of selected proteins into cilia. The IFT protein complexes IFT-A and IFT-B polymerize at the base of the cilium to form an anterograde train that facili...

Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps.
www.nature.com/articles/s41...

1 year ago 87 28 2 2

Thank you! Can you also add @peronegaia.bsky.social ??

1 year ago 2 0 1 0
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