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Posts by MRC Integrative Epidemiology Unit

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Deciphering the influence of socioeconomic status on brain structure: insights from Mendelian randomization - Molecular Psychiatry Molecular Psychiatry - Deciphering the influence of socioeconomic status on brain structure: insights from Mendelian randomization

Read the paper: www.nature.com/articles/s41...

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Read more in David's blog post: ieureka.blogs.bristol.ac.uk/2026/03/19/s...

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Socioeconomic Status Alters Your Brain Structure Podcast Episode · The Last Show with David Cooper · March 18 · 11m

This week IEU's Dr David Hill was a guest on The Last Show podcast. David was talking about his research into socioeconomic status and brain health in later life. podcasts.apple.com/ca/podcast/s...

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A comprehensive new tool for exploring how genetic variation influences outcomes, of relevance to everything driven by phenotypes, which encapsulates many domains, from how drugs work to how natural selection works ... / cont

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The Human Genotype-Phenotype Map is an integrated discovery engine designed to help genetic epidemiologists move from a list of SNPs to a systemic understanding of pleiotropic architecture.
Read more in @elmorea.bsky.social's blog post: ieureka.blogs.bristol.ac.uk/2026/03/11/g...

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Before the UK‑wide disposable vape ban, we asked 22 young adults who used disposables about the ban and how they might respond. Some reactions were expected, others were more concerning: “I’d probably start smoking."

Read more about our latest study, led by Richie Carr: doi.org/10.1371/jour...

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Higher BMI from menarche to age 40 protects against breast cancer, but this effect attenuates when controlling for prepubertal adiposity, write Power et al. from @uob-ieu.bsky.social in @science.org Advances www.science.org/doi/... 🧪

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Prediction models for longitudinal trajectories of depression and anxiety: a systematic review Prediction of atypical health trajectories may enable early intervention. We systematically reviewed the existing literature on models for predicting …

Our systematic review highlights a lack of robust models to forecast future risk of persistent or worsening anxiety and depression, especially in child/adolescent populations where there is opportunity for early intervention.

Read: tinyurl.com/h7vjzjch
@bristolbrc.bsky.social @uob-ieu.bsky.social

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Review finds lack of risk calculators to predict long-term depression and anxiety - Bristol Biomedical Research Centre There are very few risk calculators to predict how symptoms of anxiety and depression will change over the course of a person’s life, according to a recent review of past research. This is the first s...

📢 New research paper!
🫂Our review shows there's a lack of risk calculators to predict long-term #depression and #anxiety

👉 www.bristolbrc.nihr.ac.uk/review-finds...

#MentalHealth #MentalHealthResearch
@sjfairweather.bsky.social @uob-ieu.bsky.social

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Epidemiology research programme makes real-world difference in fight against cancer – IEUREKA!

Our previous @cancerresearchuk.org-funded programme ended at the end of January. In this new blog post we reflect on the difference that programme has made to prevention and early detection of cancer. ieureka.blogs.bristol.ac.uk/2026/02/02/i...

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2026: OCEP launch | MRC Integrative Epidemiology Unit | University of Bristol

We are excited today for the start of the new Obesity-related Cancer Epidemiology Programme, funded by @cancerresearchuk.org. Read more in our news story: www.bristol.ac.uk/integrative-...

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Brilliant inaugural lecture by Professor Evie Stergiakouli on her career so far, @uob-ieu.bsky.social so lucky to have secured her talents right from its inception. Thx Evie!

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January: Higher maternal blood pressure increases the risk of pregnancy complications | News and features | University of Bristol

We found that higher maternal blood pressure increases the risk of multiple adverse pregnancy outcomes, highlighting the importance of interventions aimed at controlling blood pressure in the population.

Check out this press release for more details: www.bristol.ac.uk/news/2026/ja...

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After five years of collaboration with the MR-Preg group, I'm excited to share our latest Mendelian randomization study on maternal blood pressure during pregnancy and perinatal health, published today in BMC Medicine 🎉

Thanks to all those involved!

rdcu.be/eY0nB

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Why evidence matters in health research Professor George Davey Smith explains why he encourages scientists to look for ways they might be wrong.

Newspaper headlines often share compelling quick fixes for health issues - but often the realities of what causes health conditions is more complex. In this blog post @mendelrandom.bsky.social explains why he encourages scientists to look for ways they might be wrong. www.ukri.org/blog/why-evi...

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Why ‘coffee causes cancer’ headlines get it wrong Coffee causes cancer. Red wine protects your heart. Chocolate cuts diabetes risk. These headlines catch the eye, but are they true?

Happy New Year! To start the year, do read this @ukri.org interview with our director @mendelrandom.bsky.social, recipient of the prestigious MRC Millennium Medal. medium.com/@UKRI/why-co...

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Congratulations Professor George Davey Smith on being awarded the Medical Research Council Millennium Medal
@uob-ieu.bsky.social @bristoluni.bsky.social, @ukri.org

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November: MRC Millennium Medal awarded to preeminent British health scientist from Bristol | News and features | University of Bristol

Many congratulations to IEU's Director, Professor George Davey Smith. This week he is being awarded the prestigious Medical Research Council Millennium Medal. @childrenofthe90s.bsky.social @bristoluni.bsky.social @ukri.org www.bristol.ac.uk/news/2025/no...

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November: MRC Millennium Medal awarded to preeminent British health scientist from Bristol | News and features | University of Bristol

Many congratulations to IEU's Director, Professor @mendelrandom.bsky.social. This week he is being awarded the prestigious Medical Research Council Millennium Medal. @childrenofthe90s.bsky.social @bristoluni.bsky.social www.bristol.ac.uk/news/2025/no...

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Huge congratulations to our director @mendelrandom.bsky.social on this prestigious medal, which MRC is awarding to him next week.

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Clarivate Highly Cited Researchers 2025 The Highly Cited Researchers 2025 list identifies and celebrates individuals who have demonstrated significant and broad influence in their fields of research. Through rigorous selection criteria and ...

IEU is again represented strongly in the latest Clarivate Highly Cited Researcher awards. Congratulations to the nine IEU researchers in the latest list (over a thousanth of all the awards). clarivate.com/highly-cited...

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Scientists call for the clock change to be DITCHED entirely In the early hours of tomorrow morning the clocks will jump back an hour. But rather than celebrate having a lie-in, experts have warned it could have a slew of negative consequences.

As the clocks changed last weekend, the Daily Mail published an article about the health impacts of these twice-yearly changes, including an interview with IEU's @meldelange.bsky.social www.dailymail.co.uk/sciencetech/...

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October: Cholesterol dementia study | News and features | University of Bristol

Cholesterol-lowering drugs could reduce the risk of dementia, study finds - read about this important new research from the MRC Integrative Epidemiology Unit www.bristol.ac.uk/news/2025/oc...

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September: Adiposity and cancer | News and features | University of Bristol

How fat is distributed in people’s bodies could make a difference to their risk of certain cancers. Read more in our latest press release. www.bristol.ac.uk/news/2025/se...

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What are the biological mechanisms underlying the association between smoking, smoking cessation and mental health: a triangulation approach - GW4 BioMed MRC DTP Project Code MRCPHS26Br Taylor G Project Type Dry lab Research Theme Population Health Science Project Summary Download Summary What are the biological mechanisms underlying the association between sm...

Share: Complete your PhD in data science & epidemiology with real-world impact! Join us at @uob-ieu.bsky.social @bristoluni.bsky.social through the @gw4biomeddtp.bsky.social. Fully funded project exploring biological mechanisms linking smoking & mental health.

gw4biomed.ac.uk/what-are-the...

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Share: Complete your PhD in data science & epidemiology with real-world impact! Join us at @uob-ieu.bsky.social @bristoluni.bsky.social through the @gw4biomeddtp.bsky.social. Fully funded project exploring co-use of e-cigarettes, cannabis and tobacco

gw4biomed.ac.uk/understandin...

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Higher levels of interleukin-6 in patients with pleural infection are linked to more serious disease - Bristol Biomedical Research Centre Patients with a pleural infection who have higher levels of interleukin-6 in their blood or pleural fluid are likely to be more unwell than patients with lower interleukin-6 levels, a new study shows....

💡 New research paper! Can we find new ways to treat serious lung disease?

🫁 Higher levels of interleukin-6 in patients with pleural infection are linked to more serious disease 🤒
www.bristolbrc.nihr.ac.uk/higher-level...

@uob-ieu.bsky.social @nihrexeterbrc.bsky.social @bristolaru.bsky.social

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Details | Working at Bristol | University of Bristol

Do you have strong research software engineering skills who wants to make a real-world impact? We are looking for a Senior Research Associate/Research Fellow in Genetic Epidemiology Research (Software Engineer). Apply by 14th September. www.bristol.ac.uk/jobs/find/de...

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Explaining science through baking with Bake Off finalist Josh Smalley and Dr Paternoster
Explaining science through baking with Bake Off finalist Josh Smalley and Dr Paternoster YouTube video by Medical Research Foundation

🧁🧬 Great British Bake Off finalist @joshpsmalley.bsky.social joined @lpaternoster.bsky.social to turn her genetic research into delicious vanilla & passionfruit cupcakes - with a scientific twist.

🎥 Watch the full video here: youtu.be/xcc200LksM4?...

@bristolbrc.bsky.social @uob-ieu.bsky.social

7 months ago 1 1 0 0
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Chronic inflammation messes with your mind. Here's how to calm it From depression to dementia, we are now realising the profound impacts of long-term inflammation on the brain. A better understanding of the underlying mechanisms is unlocking new treatments to protec...

New Scientist cover story! Latest issue puts a spotlight on the work of Golam Khandaker & others in our Immunopsychiatry programme, as well as other groups, in uncovering links between inflammation & mental health. @childrenofthe90s.bsky.social www.newscientist.com/article/2491...

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