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What!

www.nature.com/articles/s41...

Cartoon showing key challenges in evolutionary cell biology. This schematic illustrates four central challenges in the field: (1) integrating cell biology with evolutionary theory and experimental evolution, (2) bridging the genotype–phenotype gap, (3) identifying and developing new model systems, and (4) incorporating ecological context into evolutionary cell biology. Each quadrant highlights a conceptual hurdle that must be addressed to advance the discipline.

@gautamdey.bsky.social, @fritzlaylin.bsky.social, @alebenoit.bsky.social and @eelcotromer.bsky.social discuss how the field of evolutionary cell biology works to understand how cells evolve & diversify, highlighting current challenges & the future outlook.
journals.biologists.com/jcs/article/...

Super-fun, absolutely WONDERFUL paper from Gohta Goshima

www.nature.com/articles/s41...

Happy new year! I've so enjoyed the end-of-year lists of people's favorite papers from 2025, so I made a list of 16 #lipidtime studies from 2025 that I found interesting. Here they are in no particular order (please add more if you would like!), and here's to much more exciting science in 2026! 🧪

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Wild and amazeballs

Fission yeasts lookup

Yay - and also thank you to the three reviewers!

/)/)
( . .)
( づ♡

Got to like every time spandrel shows up

If you use PomBase, please help us to demonstrate our value, and make improvements by completing our user survey www.surveymonkey.com/r/7GXJL6X

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TRANSCRIPTION FACTOR YAY

Homeostasis! Membranes! Evolution! Yay

Ahhh CUTE!!!

Ikr!

Regulation of cell proliferation by a novel feedback system on Cdk function The proliferation of eukaryotic cells is regulated by a complex network of regulatory systems that promotes efficient cell cycle progression and ensures proper responses to the environment. Despite th...

Minimal CDK continues delivering 💥

www.biorxiv.org/content/10.1...

Lenny says yay

Enhanced hybridization-proximity labeling discovers protein interactomes of single RNA molecules - Nature Communications Systematic discovery of proteins interacting with low-abundance RNAs is challenging. Here, the authors develop an enhanced HyPro technology to identify proteins associated with compact RNA compartment...

Our paper describing enhanced hybridization-proximity labeling technology is finally out! Enhanced HyPro can identify proteins associated with small RNA compartments and even some individual transcripts, such as pathological C9orf72 transcripts: www.nature.com/articles/s41...

Schematic of MAPK signalling in fission yeast, budding yeast and Metazoa. No MAPK scaffold was known for ERK-like MAPK in fission yeast, as opposed to budding yeast Ste5 and metazoan KSR1/2.

Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction!

Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1

doi.org/10.1101/2025...

Very pretty - congrats!

Ahh congrats!

;))

Yay!!! 🤗🤗🤗

Please visit our newly refreshed and updated website mcclellandlab.com We seem to be hard to find on Google for some reason, any tips from website savvy people?? 🙏

Cute!

Ahh so beautiful

YES

Screenshot of the SOG home page.

We are pleased to share the Schizosaccharomyces orthogroup web resource (fsnibs10.github.io/SOG/) with the pombe community.

Congrats on your first paper 🤗