Yayy!!

@exdrososcientia.bsky.social an I were delighted to host @franbottanelli.bsky.social for an amazing seminar on nanoscale understanding of membrane trafficking pathways 🔬

We are grateful to @biochemsoc.bsky.social for sponsorship to host an international speaker 🙌

Neuroscientists on a field trip!
What to do when the lab is closed for heating updates and window repairs? Leave the flies, pipettes and cultures behind for some fossil hunting and fish&chips at the Yorkshire coast.

We're doing the same thing!! It's does make a massive difference in my experience.

That would be great!!! Join us for NeuroBioUK 😊

I didn't manage to go this year, but half of the lab is there :) Hope to catch up soon!

Co-creating handbooks in research teams resource - taking the worry out of the process for anyone who wants to create a lab handbook with others, regardless of their role, experience or career stage. Designed by Gina Vong, Dr Ines Hahn and Dr Alex Payne-Dwyer
figshare.com/articles/dat...

Same here!

The date for the fourth!!! #NeuroBioUK26 is fixed - join us September 11th 2026!

Picture of a robin

ready for spring

That's great, thanks so much!

Ha! 😅 very interested in those inhibitors, which ones would you recommend and have people tested them in flies before?

Good point! We went with beta because sgg leans that way and we used beta in the mammalian+in vitro experiments. Didn't feel that we can make a statement about alpha. Would love to hear your overall thoughts - always up for chatting! I did not know you're a York alumni, very cool and small world! 😊

Fly primary neurons arranged in a circle, tubulin labelled in green, actin in magenta.

Our article on how GSK3b controls microtubule bundling in axons is live 🎉
Here's our #notthecover attempt
www.pnas.org/doi/10.1073/...

Great q!! That's what we're working on next atm - we think that is that it's active in the growth cone centre to allow MTs to explore, either inactivated at the membrane (via Akt) to promote or activated (via sema signalling) to block outgrowth

This work has been a long time coming and we were supported by amazing scientists making tackling GSK-3β complexity possible - thanks so much Andre, Marvin, Gareth, Lubna, Alex, Sanjai, Hayley and Antony!!

GSK-3β coordinates axonal microtubule organization through Shot and Tau | PNAS Glycogen Synthase Kinase 3β (GSK-3β) is a key coordinator of neuronal development and maintenance; hyperactive GSK-3β is linked to neurodevelopment...

www.pnas.org/doi/10.1073/...

Images of fly primary neurons that express active or inactive GSK3beta stained for tubulin and a midel summarising how we think Shot and Tau microtubule binding is affected by low, optimal and high kinase activity.

"Your article has been published" 🎉 We found there's a sweet spot of GSK-3β activity required to keep axonal microtubules bundled in 🪰🐀. Too much/little affect how Tau and Shot associate with microtubules leading to microtubules that loose bundling and resemble a bowl of cooked spaghetti 🍝

Image of The Reyton's Kids Off The Estate record

This morning's album of the day featuring Yorkshire's @thereytons.bsky.social Kids Off the Estate was playing in a record shop and I had to get it on the spot

Image of vinyl of Puscifer's new album Normal Isn't

Since the start of the year I've been kicking off my mornings with an 'album of the day'. Today's pick: Puscifer's fantastic new album 'Normal Isn't'. Complex rock with goth and punk vibes, MJK and Carina's ethereal voices, excellent lyrics - highly recommend!

At a time when the UK should be capitalising on its global reputation as a great place to do science, this is an enormous own goal. I am so sorry for all those who jobs are going to be impacted.

Thank you very much for the invitation, I had a great time and it was lovely to see you again!

Need a reason to join next year's #NeuroBioUK? Here it is :)
Thanks Sally for the amazing review
focalplane.biologists.com/2025/10/06/n...

The poster hall at the National STEM learning centre with astronauts suspended from the ceiling.

Poster boards are ready and waiting for #NeuroBioUK - let’s get this science party started 🥳

We're kicking off the third #NeuroBioUK - an exciting day full of neuronal cell biology ahead!
Massive thank for @bscb-official.bsky.social support and a shout out to our industry sponsors!

hiya!

In contrast to tonight's sky I don't want to be dramatic, but there's only two more days left to submit an abstract to be considered for a talk at #NeuroBioUK
neurobiouk.sites.sheffield.ac.uk/registration

🚨The deadline for a talk submission is approaching soon - don't miss your spot!! We can't wait to see you in York 😊
For details check out our website:
neurobiouk.sites.sheffield.ac.uk/registration

Really, really amazing conference. We went last year and the scientific programme and atmosphere were incredible! I 100% recommend attending + submitting an abstract for a talk - spread the word! 🧠

a man wearing a chef 's hat is standing over a pile of dough . ALT: a man wearing a chef 's hat is standing over a pile of dough .

🤣 Why, is this you in the lab? 😉