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Posts by Edna Cukierman - Tumor Microenvironment

Final days to secure your spot for this exciting webinar on Monday, April 27 on "Stromal Architects: ECM, Fibroblasts, and the Cancer Niche" with @tme-caf-ecm.bsky.social and Yash Chhabra!!! Register now! forms.gle/7LoqzKp891PQ...

6 hours ago 2 2 0 0
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Don’t miss poster #4920 this morning! #AACR26 @theaacr.bsky.social
#MariiaDmitrieva will show how #multiplexIF of human #pancreatic 3D CAF/ECM units, using @biotechne.bsky.social COMET & HORIZON, assigns pro- vs anti-tumor functional values.
@foxchasecancer.bsky.social

2 days ago 1 0 0 0

Excited to share our research together with #risingStar #YashChhabra on the role that fibroblasts/ECM functional units play in fertilizing the tumor soil, and show some possible means for drying the land.
@foxchasesurgonc.bsky.social and @templeunivpress.bsky.social

3 days ago 2 0 0 0

I only attended ( was not inducted) 😜

3 days ago 0 0 0 0
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#AACRFellows and Past President Charles L. Sawyers discusses "How Cancer Cells Escape Targeted Therapy by Changing Identity" during the Opening Plenary Session at #AACR26.

3 days ago 5 2 0 0
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CAFs as orchestrators of extrinsic hallmarks of cancer

3 days ago 1 0 0 0
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I knew it! 😂💜😎 #AACR26 @theaacr.bsky.social

3 days ago 2 0 1 0
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👇🏻 highly recommended #AACR26. EDU session on shaping the #TumorMicroenvironment to the benefit of patients

5 days ago 2 0 0 0

It was a true honor to witness the @theaacr.bsky.social #AACR26 Fellows Class
Induction at tonight’s Dinner 😎

5 days ago 2 0 0 0
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Educational Program will feature prevention, early detection, AI, chemistry, and more - AACR Annual Meeting News This year, Educational Sessions and Methods Workshops will be available to all attendees as part of their standard meeting registration at no additional cost. Two days of cross-disciplinary programmin...

Educational Program @theaacr.bsky.social #AACR26 #AACR2026

😎 See you all in San Diego

www.aacrmeetingnews.org/educational-...

4 weeks ago 0 0 0 0
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Now hiring: Tenure-track faculty (Asst/Assoc/Full) in Computational & Experimental Protein Design at Fox Chase Cancer Center, Philadelphia PA   Join the Cancer Signaling & Microenvironment Pro... Now hiring: Tenure-track faculty (Asst/Assoc/Full) in Computational & Experimental Protein Design at Fox Chase Cancer Center, Philadelphia PA   Join the Cancer Signaling & Microenvironment Program at ...

The Cancer Signaling & Microenvironment Program at Fox Chase Cancer Center is looking for tenure track faculty (assist./assoc./full) in computational & experimental protein design. CV & 3-page research statement by Feb 15.

More info here:
www.linkedin.com/feed/update/...

Questions: DM/Email me.

3 months ago 12 9 0 1
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Heterocellular crosstalk and architecture of the pancreatic tumour microenvironment Nature Reviews Cancer, Published online: 16 January 2026; doi:10.1038/s41568-025-00905-9Pancreatic ductal adenocarcinoma is defined by a fibroinflammatory microenvironment, which influences both disease progression and therapy response. In this Review, Arnold et al. outline our current understanding of the complex interplay between the stromal elements of the tumour microenvironment in pancreatic ductal adenocarcinoma and present ways we might use this knowledge to develop better therapeutic strategies for patients with pancreatic cancer.
3 months ago 13 8 0 0
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Opportunities and challenges of targeting cGAS–STING in cancer - Nature Reviews Cancer In this Review, Lu et al. discuss the dual role of the cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS)–stimulator of interferon genes (STING) pathway in cancer, emphasizing its involvement in both tumour suppression and promotion. They highlight the diverse sources of pathway activation and suggest that this functional duality may underlie the limited clinical success of cGAS–STING targeting in cancer therapy.

Weekend reading 🚨
A comprehensive #Review on the dual role of the #cGAS#STING pathway in cancer, emphasizing its involvement in both tumour suppression and promotion, which might underlie the limited clinical success of cGAS–STING targeting in cancer therapy.
📖👇

3 months ago 3 2 0 0
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Mapping proteins, one side chain at a time Roland Dunbrack Jr. will receive the ASBMB DeLano Award for Computational Biosciences at the ASBMB Annual Meeting, March 7–10, just outside of Washington, D.C.

My awesome Co-Program Leader, colleague, and dear friend @rolanddunbrack.bsky.social was featured at @asbmb.bsky.social

Read all about him and the terrific research he leads at the #FoxChaseCancerCenter

Mapping proteins, one side chain at a time www.asbmb.org/asbmb-today/...

3 months ago 9 2 0 0
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Lerche, Mathieu, @johannaivaska.bsky.social @ivaskalab.bsky.social et al. reveal that newly synthesized #integrins can bypass the Golgi to be actively delivered to specific plasma membrane regions, where they enhance cell protrusion and #adhesion. rupress.org/jcb/article/...

4 months ago 30 12 0 0

Very fitting today… #worldPancreaticCancerDay

5 months ago 9 1 2 0
The Fred Hutch Cancer Center sign and fall leaves. View from my window early morning at Seattle

The Fred Hutch Cancer Center sign and fall leaves. View from my window early morning at Seattle

Honored to share my team’s research on translational #PancreaticCancer (@foxchasesurgonc.bsky.social) at today’s Memorial #SupriyaSahaGISeminar

Excited to see my
host, & friend #KugelSita and learn about her’s & colleagues’ impactful new discoveries at the @fredhutch.org

5 months ago 7 0 0 0
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x.com/nobelprize/s...
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.” @thenobelpeaceprize.bsky.social

6 months ago 2 0 0 0
From left to right, Elda, myself, and  Zobeida smiling with the AACR Pancreatic Cancer Research meeting hall in the background

From left to right, Elda, myself, and Zobeida smiling with the AACR Pancreatic Cancer Research meeting hall in the background

#AACRPan25 #PancreaticCancer research
@theaacr.bsky.social

#ItTakesAVillage

I feel very lucky to have such amazing friends and colleagues!!
#EldaGrabocka & @zcmlab.bsky.social

#WomanInSTEM

6 months ago 19 2 1 0
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Yan Leyfman: γδ T Cells as Scalable “Off-the-Shelf” Therapy for Solid Tumors - OncoDaily Yan Leyfman: γδ T Cells as Scalable “Off-the-Shelf” Therapy for Solid Tumors / Adnan Moinuddin, Ali A. Ashkar, Allyson E. Moore, Ana L. Portilloa, cancer,

γδ T Cells as Scalable “Off-the-Shelf” Therapy for Solid Tumors - Yan Leyfman

@yleyfman.bsky.social

oncodaily.com/voices/yan-l...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #SolidTumors

6 months ago 5 1 0 0
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This is how to kick a talk out of the game park! A true #HomeRunTalk by @jayeperview.bsky.social at the selected talks from posters closing the #AACRPan25 @theaacr.bsky.social meeting

First talk out of her own lab
@thegardinerlab.bsky.social
#Proudisima to have played a small role 😎💜

6 months ago 16 4 1 0
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Next up in our Article Showcase is a featured selection from Edna Cukierman, Senior Editor of Tumor Biology: “Targeting Pancreatic Cancer Cell Stemness by Blocking Fibronectin-Binding Integrins on Cancer-Associated Fibroblasts” buff.ly/v2ICc8M @tme-caf-ecm.bsky.social

6 months ago 2 1 1 0
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#AACRPan25 @theaacr.bsky.social
Being a #ProudisimaPI & the opportunity of becoming a #ProudisimaColleague
is the best feeling ever!

#pancreaticcancer #foxchasecancercenter @jayeperview.bsky.social @debvendramini.bsky.social @saumyamarumdphd.bsky.social #AlexDolskii @brookepereira.bsky.social

6 months ago 14 2 0 0

Looking forward to day 2 (chaired by yours truly 😎)
#AACRPan25 #PancreaticCancer
@theaacr.bsky.social

6 months ago 2 0 0 0
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The first day of the @theaacr.bsky.social #AACRPan25 meeting in Boston started with a bang!!! It was all about #PancreaticCancer Interception

and what a list of speakers!
A few pics of #Day1 💜

6 months ago 8 0 1 0
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Read the abstracts from @theaacr.bsky.social Special Conference in Cancer Research: Advances in Pancreatic Cancer Research here in the September 15 issue of Cancer Research: buff.ly/ncicLEB

#AACRpan25

6 months ago 2 1 0 0
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On my way to #AACRPan25
#PancreaticCancer 💜

6 months ago 1 0 0 0

I am so lucky to count with the amazing #oneandonly @rolanddunbrack.bsky.social as my colleague and thrilled to count him as my dear friend!!!
#congratulations!!!

7 months ago 4 2 1 0
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a breaking news sign is displayed on a blue and red background ALT: a breaking news sign is displayed on a blue and red background

#ExtraExtra the amazing @saumyamarumdphd.bsky.social just joined our #GIMedicalOncology and the Cancer Signaling & Microenvironment Program as our newest #AssistantProfessor at #FoxChaseCancerCenter #PancreaticCancer #TumorMicroenvironment

We wish you the #BestofLuck!!!!! 💜💜💜

7 months ago 5 0 0 1
The lab-team and significant others

The lab-team and significant others

Jaye showing off her Friends of Fox Chase Cancer Center new jacket

Jaye showing off her Friends of Fox Chase Cancer Center new jacket

#ProudisimaPI

Traditional #CukiermanLab ‘s summer falafel & empanadas day; at yours truly’s house!

it was #bittersweet; I am enormously happy to be so sad… 🥹

We were wishing #bestofluck to the amazing @jayeperview.bsky.social who is opening @thegardeningbard.bsky.social at #Tufts in September!!

8 months ago 14 0 0 0