WOW! I have been waiting to see this complex for MANY years!

More than 2 decades ago the PINK1 protein was found to be linked to Parkinson's disease, but its structure and how it was activated was not known. Until @science.org today. A triumph for cryo-EM and structural biology, introducing new targets for drug intervention.
www.science.org/doi/10.1126/...

Structural dynamics of DNA unwinding by a replicative helicase - Nature Cryo-electron microscopy structures of DNA helicases in various conformations provide insight into an ATP-hydrolysis-dependent ‘entropy switch’ that drives unwinding of DNA for replication, with probable conservation across viral and eukaryotic systems.

Nature research paper: Structural dynamics of DNA unwinding by a replicative helicase

https://go.nature.com/3XWtN0b

Gotta love well-aligned beta-sheets