Hot off the press 🚨 Epidemic spreading between regions is often modelled on a network 🕸️ But how do we describe this process properly? Here, we show how to build a linear transport operator at the network scale, by coarse-graining local advection-reaction-diffusion within edges. shorturl.at/0tAN8
Posts by Christoffer G. Alexandersen
Global brain activity links subcortical degeneration to cortical tau progressively across Braak regions over early Alzheimer disease stages www.biorxiv.org/content/10.64898/2026.01...
Job alert🚨I am advertising a 2-year postdoctoral position to work on the mathematics of plant morphogenesis @mpipz.bsky.social. Candidates with interests in mathematical modelling, mechanics, or biophysics are strongly encouraged to apply. 🌱Reposts are appreciated!
jobs.mpipz.mpg.de/jobposting/4...
@danisbassett.bsky.social @mxhend.bsky.social @gsbrennan.bsky.social
❗🧠 New review in IEEE RBME
How network math models are reshaping how we think about neurodegenerative disease, from brain dynamics to disease progression
"Network models of neurodegeneration: bridging neuronal dynamics and disease progression"
ieeexplore.ieee.org/document/113...
🧠 New preprint 🧠
We review comp. models of brain activity and protein spread in neurodegeneration, and argue that linking them is key to understanding and intervention
With @danisbassett.bsky.social Y. Iturria-Medina
@mxhend.bsky.social K. Brynildsen @gsbrennan.bsky.social
arxiv.org/abs/2509.05151
⭐New preprint: "A multiscale theory for network advection-reaction-diffusion"
with @alaingoriely.bsky.social and Emilia Cozzolino
arxiv.org/abs/2509.06546
Modelling cerebrovascular pathology and the spread of amyloid beta in Alzheimer’s disease: royalsocietypublishing.org/doi/10.1098/... #ProcA #Alzheimers #biophysics
In this paper, we connect local damage to brain vasculature to global progression of toxic proteins leading to neurodegenerative diseases.
royalsocietypublishing.org/doi/epdf/10....
We identify situations where disease initiation can be caused by focal hypoperfusion following vascular injury.