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Posts by Christoffer G. Alexandersen

Hot off the press 🚨 Epidemic spreading between regions is often modelled on a network 🕸️ But how do we describe this process properly? Here, we show how to build a linear transport operator at the network scale, by coarse-graining local advection-reaction-diffusion within edges. shorturl.at/0tAN8

1 week ago 18 9 1 0

Global brain activity links subcortical degeneration to cortical tau progressively across Braak regions over early Alzheimer disease stages www.biorxiv.org/content/10.64898/2026.01...

2 months ago 2 2 0 0
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Job alert🚨I am advertising a 2-year postdoctoral position to work on the mathematics of plant morphogenesis @mpipz.bsky.social. Candidates with interests in mathematical modelling, mechanics, or biophysics are strongly encouraged to apply. 🌱Reposts are appreciated!

jobs.mpipz.mpg.de/jobposting/4...

2 months ago 25 27 0 2

@danisbassett.bsky.social @mxhend.bsky.social @gsbrennan.bsky.social

3 months ago 3 0 0 0
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❗🧠 New review in IEEE RBME

How network math models are reshaping how we think about neurodegenerative disease, from brain dynamics to disease progression

"Network models of neurodegeneration: bridging neuronal dynamics and disease progression"
ieeexplore.ieee.org/document/113...

3 months ago 11 7 1 0
Preview
Network Models of Neurodegeneration: Bridging Neuronal Dynamics and Disease Progression Neurodegenerative diseases are characterized by the accumulation of misfolded proteins and widespread disruptions in brain function. Computational modeling has advanced our understanding of these proc...

🧠 New preprint 🧠
We review comp. models of brain activity and protein spread in neurodegeneration, and argue that linking them is key to understanding and intervention
With @danisbassett.bsky.social Y. Iturria-Medina
@mxhend.bsky.social K. Brynildsen @gsbrennan.bsky.social
arxiv.org/abs/2509.05151

7 months ago 8 2 0 0
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⭐New preprint: "A multiscale theory for network advection-reaction-diffusion"

with @alaingoriely.bsky.social and Emilia Cozzolino

arxiv.org/abs/2509.06546

7 months ago 16 2 0 2

Modelling cerebrovascular pathology and the spread of amyloid beta in Alzheimer’s disease: royalsocietypublishing.org/doi/10.1098/... #ProcA #Alzheimers #biophysics

1 year ago 8 5 1 0
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In this paper, we connect local damage to brain vasculature to global progression of toxic proteins leading to neurodegenerative diseases.
royalsocietypublishing.org/doi/epdf/10....
We identify situations where disease initiation can be caused by focal hypoperfusion following vascular injury.

1 year ago 11 4 0 1