On top of the slowdown in grantmaking I wrote about last week - this is another deeply worrisome trend for scientists, physicians, patients, families, and basically anyone who wants new treatments and new tools to promote health. 🆘🧪🥼
open.substack.com/pub/elizabet...
The team worked incredibly hard to get this out the door in time to share with grant review committees, and I am so grateful for their effort.
If you have thoughts, questions, or ideas for where this platform could (or should) go next, we would love to hear from you.
On a personal note: as an early stage PI, it’s become clear how hard it is to sell any new project to grant reviewers without a proven track record. This one is a major milestone for us, and just a snapshot of the momentum our lab is building and what we’re capable of.
Immensely proud of this team effort led by Ryan and Stefan @bffswithbiology.bsky.social @stefan-golas.bsky.social. Could not have asked for a better team. This is just the beginning.
Evolution navigated billions of challenges to get to us to where we are today. Directed evolution compresses this to a 1D axis.
Imagine if you could sample 200 dimensions at once, with data to boot 📈
First @chorylab.bsky.social PACE preprint on our new system to tackle this: bit.ly/turboprance
A Purpose-Built Open Source Liquid Handler for Industry-Class Automated Experiments www.biorxiv.org/content/10.64898/2026.03...
An autonomous system for multi-objective continuous evolution at scale www.biorxiv.org/content/10.64898/2026.03...
NIH research grant funding rates plummeted in 2025. Agency acknowledges young investigators are losing out as result of multiyear funding policy imposed by White House. | Science | AAAS www.science.org/content/arti...
Full open access paper available here: www.cell.com/cell-reports...
A noninvasive estrous tracking toolkit for wild mice. Standard genetic engineering methods built for lab mice do not translate to non model rodents. This helps overcome that barrier and may enable engineering in many other species.
So proud this multi-year effort is finally out. Led by my exceptional collaborator Joanna Buchthal, who put her blood, sweat, and literal tears into making a real impact for communities impacted by Lyme disease. bit.ly/MAT-tracking
More papers soon.
Learn more & support: miceagainstticks.com
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Happy holidays from all of us in the Chory Lab and our lab neighbors at Duke!☃️🎉 @chorylab.bsky.social @dukeubme.bsky.social
There’s fair concern around a few African ancestry associated-SNPs w Casgevy. Suspect if in enchancers/promoters, deleterious effects would take much time to tell tho.
What an endorsement!
Exciting opportunity @pasteur.fr for junior scientists aiming to create their research group !
A foundation model for microbial growth dynamics www.biorxiv.org/content/10.64898/2025.12...
They all do! But I automate my calendar deadlines and dates in emails are particularly helpful for that when you have 55 letters to submit :)
The weirdest move is automated letter-request systems sending emails with no deadline included.
2011 v 2025. Variance not statistically significant.
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
We're thrilled to announce SeqHub, an AI-enabled platform for biological sequence analysis. SeqHub brings together sequence search, genome annotation, and data sharing in one place.
Teamwork makes the scream work. Happy Halloween from the Chory lab! 🦖🎃👻
The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍
Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE
Interested in using microbes to degrade plastics?
We made the discovery that two breakdown products of PET, MHET and BHET, are readily taken up by E. coli cells
Our latest preprint exploits this surprise to realize improvements in cell-based upcycling
www.biorxiv.org/content/10.1...
The things Apple will do to procrastinate improving Siri
Reviewer #3:
Major Comments:
1) The absence of ref Ahlqvist et al. (2024, JAMA) calls the manuscript’s central claims into question. This selective omission undermines the work’s credibility. Major revisions required prior to resubmission.
::cough peer review cough:: @washingtonpost.com
The @washingtonpost.com story on Tylenol & autism leaves out a MAJOR 2.5M sibling-controlled study of children in Denmark, which "found no evidence that acetaminophen use during pregnancy was associated with children’s risk of autism, ADHD or intellectual disability." jamanetwork.com/journals/jam...
Years in the making — Mice Against Ticks is on @60Minutes this Sunday!
🎥 Sneak peek: www.tiktok.com/@60minutes/v...
🌐 Join the fight! miceagainstticks.org
Huge cheers to our amazing team, brilliant collaborators & island communities for bringing this story to life! 💛
#LymeDisease #MITMediaLab
