Fast approximate loss change for active learning on imbalanced data
doi.org/10.1016/j.as...

Cell-Free Protein Synthesis-Based Biosensing Platforms for Clinical Diagnostics Cell-free protein synthesis (CFPS) is an in vitro platform that enables rapid protein production using cell extracts, energy sources, and genetic templates. Owing to its fast response, elimination of ...

Cell-Free Protein Synthesis-Based Biosensing Platforms for Clinical Diagnostics
doi.org/10.1021/acss...

GROQ-seq Datasets Across Transcription Factors (LacI, RamR, VanR), T7 RNA Polymerase and TEV Protease www.biorxiv.org/content/10.64898/2026.04...

Very proud of this work and all the efforts from my team and collaborators on this! You can now use DGRs for in vivo targeted hypermutagenesis in E. coli. We also included some early proof of concept in Yeast thanks to @seth-shipman.bsky.social !

Artificial cell-free pathway for carbon-efficient glycerol-HCO3− conversion to l-aspartate with ATP and cofactor trade-offs
doi.org/10.1016/j.bi...

Noncanonical amino acids enable plug and play vaccine platform in the ALiCE cell free system - npj Vaccines npj Vaccines - Noncanonical amino acids enable plug and play vaccine platform in the ALiCE cell free system

Noncanonical amino acids enable plug and play vaccine platform in the ALiCE cell free system
doi.org/10.1038/s415...

PhD position in the Niederholtmeyer Lab (Straubing Germany) on feedback control of dynamic condensate assembly and disassembly

edu.nl/7v364

Deadline: 26/04
@hniederho.bsky.social

#SynCell #SyntheticCell

Engineered Vibrio natriegens lysate can replace multiple components of cell culture media
doi.org/10.64898/202...

Interested in synthetic biology & microbiomes? 🧬🧫
We are recruiting a PhD student to develop biosensors to study microbe–microbe & microbe–host interactions.
In beautiful Lausanne, Switzerland🏔️⛵
@dmf-unil.bsky.social @fbm-unil.bsky.social
Apply by 24.05.2026 👇
shorturl.at/6X7M4
Boosts appreciated!

Our new Complex Systems Lab website www.complexsystemslab.org is now available. Still under construction, but soon full power with our research areas, publications, teaching, outreach, news and highlights. Stay tuned. @marktas.bsky.social @jordiplam.bsky.social

De novo-designed ribozyme-controlled riboregulator for cell-free diagnostics
share.google/xeD1QF1U5Oo4...

On June 18, the Institut Pasteur is organizing the third edition of its symposium, “Artificial Intelligence in Biology and Health”, in the Émile Duclaux lecture hall. The event will bring together researchers working at the intersection of AI with biomedical sciences to discuss opportunities and challenges in this exciting and rapidly evolving field.

AI in Biology & Health symposium — 3rd edition

📅 June 18, 2026
📍 Institut Pasteur, Paris

Keynotes from EMBL-EBI, Inria & Max Planck Institute. Poster submissions still open.

Register ↘️ forms.office.com/Pages/Respon...

Physics-constrained neural ordinary differential equation models to discover and predict microbial community dynamics
doi.org/10.1073/pnas...

Dissecting host stress responses for predictable heterologous gene expression in E. coli Abstract. Predictable expression of heterologous genes remains a key challenge in biotechnology, largely due to cellular stresses imposed on the production

Dissecting host stress responses for predictable heterologous gene expression in E. coli url: academic.oup.com/nar/article/...

#microsky

Machine learning-driving optimization and spatial assembly of a cell-free system for high-yield liquiritigenin production - Advanced Biotechnology Liquiritigenin is a medicinal flavonoid whose production is constrained by inefficient plant extraction and complex chemical synthesis. To overcome this, we developed a modular cell-free multi-enzyme ...

Machine learning-driving optimization and spatial assembly of a cell-free system for high-yield liquiritigenin production
doi.org/10.1007/s443...

Tardigrade-Derived Strategy for Low-Cost Storage of Cell-Free Expression Lysates

Lipid-conjugated DNA enables on-demand delivery of lipids and proteins to synthetic cells
doi.org/10.64898/202...

Happy to share the final version of @oliviamghosh.bsky.social's paper on inferring low dimensional phenotype-fitness maps from high-throughput fitness measurements across environments. Fun collaboration with @oliviamghosh.bsky.social, @grantkinsler.bsky.social, & @petrovadmitri.bsky.social

Join us at London Calling 2026! Take this exciting opportunity to connect with some of the brightest minds in the field and explore the latest breakthroughs in Oxford Nanopore sequencing.

Want to attend as a team? Buy three, get one FREE. Tickets here: https://bit.ly/4sS0I3f #nanoporeconf

Coordinating Calvin Cycle and Glycolysis in Escherichia coli Engineering Escherichia coli to coassimilate glucose and CO2 requires rewiring central metabolism so a Calvin-Benson-Bassham (CBB) module can compete with, rather than be overwhelmed by, glycolysis. W...

Coordinating Calvin Cycle and Glycolysis in Escherichia coli
pubs.acs.org/doi/10.1021/...

Engineered microbial hydrogels with confined architecture and binary microbes for efficient hydrogen production
doi.org/10.1038/s414...

Unstructured transcription factor interactions enable emergent specificity How intrinsically disordered regions (IDRs) influence chromatin binding and nuclear organization of transcription factors (TFs) remains unclear. We employed proximity-assisted photoactivation (PAPA), ...

40 years after the cloning of Sp1, Robert Tjian and coll. discover even more properties

www.science.org/doi/10.1126/...

The scientific life of Marjory Stephenson who isolated the first enzyme from a bacterial cell!

| The Royal Society

royalsociety.org/video/the-sc...

Automated Assembly of Programmable RNA-Based Sensors
pubs.acs.org/doi/10.1021/...

Peptide-Induced Formation of Extracellular Vesicles that are Distinct From Endogenous E. coli OMVs, and Provide an Enhanced Platform for Protein Production and Purification
doi.org/10.64898/202...

A new strategy to stabilize gene circuits.
doi.org/10.1016/j.ti...

Selection-free whole genome transplantation revives dead microbes
doi.org/10.64898/202...

Toward unbiased objective functions in constraint-based modeling The objective function is important to constraint-based modeling, but setting it has traditionally been subjective, limiting predictive accuracy. We expose the biases of commonly used objective functions and propose a paradigm shift toward unbiased objective functions powered by artificial intelligence, offering a promising avenue for metabolic engineering and biomedical applications.

Online now: Toward unbiased objective functions in constraint-based modeling

With a nice shout-out for our Genomic Code paper proposing that the genome instantiates a generative model of the organism www.sciencedirect.com/science/arti...