Advertisement · 728 × 90

Posts by

Preview
FIND YOUR PLASMID - SEVA plasmids - Standard European Vector Architecture Canonical SEVA plasmids that use Golden Gate assembly to build complex genetic circuits. Find your canonical plasmid In the dropdown menu below, you can select a combination of choice for your…

🧑‍🔧⭕Let’s dissect a SEVA plasmid!
Built on a modular architecture, our plasmids make it easier to identify key vector elements.

🧬Origin of replication: more then 15 types

🔆Cargo region: such as cloning or CRSIPR.

💊Antibiotic marker: choose it from out of 10 possibilities.

👉 shorturl.at/04ZtK

1 day ago 1 0 0 0
Preview
Plasmid vectors for gene editing and genetic engineering: Design principles, efficiency, and applications Plasmid vectors remain central to gene editing and genetic engineering, providing flexible, modular, and cost-effective platforms for genome manipulation across microbial, plant, and eukaryotic…

Better vector design can make all the difference 🔬
Researchers examined how plasmid vectors are optimized for gene editing and genetic engineering. They focused on
🔧function
📈efficiency
🔀and versatility in #biotech applications
Just how SEVA likes it.👉 Read their insights here: doi.org/qz47

5 days ago 1 0 0 0
Preview
Home - SEVA plasmids - Standard European Vector Architecture Standard European Vector Architecture 4.0 Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes WHAT…

Designing plasmids shouldn’t be blocking your experiment 🧬
⭕SEVA plasmids provide a shared framework for vector construction, helping researchers work with greater flexibility and #reproducibility in biotechnology and microbial engineering.
Explore our website👉

1 week ago 1 0 0 0

🔬New model systems are helping reshape drug discovery. Nowadays there are more relevant ways to study disease biology, and improve early-stage screening. TheScientist has reviewed the latest advances in this new guide about how to use in vitro models 👉https://shorturl.at/DXbIg

1 week ago 1 0 0 0
Preview
A synthetic biology toolkit for the plasmid-dependent and thermophilic methylotroph Bacillus methanolicus Bacillus methanolicus, a unique plasmid-dependent and thermophilic methylotroph, is an ideal chassis for one-carbon (C1) biomanufacturing. Despite its…

Methanol as feedstock? Maybe not for us but… 🧪
Resarchers built new biology toolkit to help microbes grow using methanol, making them easier to engineer and more stable.
👉Read how they managed to do it:

1 week ago 0 0 0 0
Preview
Home - SEVA plasmids - Standard European Vector Architecture Standard European Vector Architecture 4.0 Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes WHAT…

👩‍🔬 The #SEVA collection keeps growing thanks to community contributions.
Add your constructs to our open plasmid repository and help improve reproducibility in #SynBio.
✨ Check the guidelines and join our mission 👉

2 weeks ago 0 0 0 0
Preview
Home - SEVA plasmids - Standard European Vector Architecture Standard European Vector Architecture 4.0 Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes WHAT…

🔬Tired of replicating that experiment and getting different results? SEVA simplifies #SynBio with a universal vector system! All SEVA #plasmids follow a standardised format. Reproducibility starts here! ⚙️👉

3 weeks ago 0 0 0 0
Preview
Magnetic mixer improves 3D bioprinting A new approach developed at MIT aims to solve a core limitation in 3D bioprinting, by actively preventing cell sedimentation within bioinks, allowing for more reliable and biologically consistent 3D…

🧬🖨️ Boosting 3D-printed tissues! MIT engineers have developed a compact magnetic mixer that keeps bioinks uniformly mixed during printing. This makes engineered tissues more reproducible and scalable – just like SEVA likes it! Check the whole story👉

3 weeks ago 2 0 0 0
Megaplasmids of the enteropathogenic species Vibrio parahaemolyticus, Vibrio cholerae and Vibrio vulnificus represent a group of novel genetic elements unrelated to other plasmids of Vibrionaceae Vibrio (V.) parahaemolyticus is a marine-associated bacterium that has previously been linked to foodborne illness associated with seafood consumption…

🔭New plasmids on the horizon! Scientists from @bfrde.bsky.social detected megaplasmids in enteropathogenic Vibrio spp. These have 80% unclassified genes! ⭕What’s more, the megaplasmids suggest a non-Vibrio origin 👉

4 weeks ago 0 0 0 0
Advertisement

💪An easy way to gain glucose! Scientists have developed a plasmid-free and inducer-free Escherichia coli to produce glucose. This may be an interesting way of reducing expenses💸. Read how they could do it👉

4 weeks ago 0 0 0 0
Preview
Find your plasmid Canonical SEVA plasmids that use Golden Gate assembly to build complex genetic circuits. Find your canonical plasmid In the dropdown menu below, you can select a combination of choice for your canonical...

🛠️✨We are the Standard European Vector Architecture (SEVA), a web-based resource in which you can choose the #plasmid that you need for your research. Our goal is to make #reproducibility, a reality. Check them out 👉

1 month ago 1 0 0 0
Preview
BACKBONE MODULES & NOMENCLATURE - SEVA plasmids - Standard European Vector Architecture Plasmid Backbone The colored arrows above the cargo and AbR modules represent the directionality of the transcription flow of that element SEVA Plasmid Nomenclature The figure sketches the expanded…

🔬SEVA format involves a set of rules to unify the scientific community.
These are visible in our #plasmid nomenclature. By order:
🦠 Antibiotic resistance marker
⭕ Origin of replication
📦 Cargo module
🛠️ Optional gadgets
Learn how it works here 👉https://shorturl.at/V5ff1

1 month ago 0 1 0 0
Preview
Light-driven metabolic makeover New-to-nature photometabolisms are highly intriguing for manufacturing but difficult to achieve. Now, Escherichia coli engineering integrates flavin-based photobiocatalysis with natural enzymatic reactions,...

Using photosynthesis as a work chain ☀️ Researchers aimed to engineer cells that can capture light and use it to produce valuable compounds. 🦠They successfully reprogrammed E. coli to perform efficient photobiosynthesis of several products! 👉

1 month ago 2 1 0 0
Preview
Mortality can induce limit cycles in a chemostat competition model between plasmid-bearing and plasmid-free organisms with allelopathy - Computational and Applied Mathematics In this paper, we study a model of competition between plasmid-bearing and plasmid-free organisms in a chemostat, where the plasmid-bearing population produces an allelopathic toxin that is lethal to…

⭕❌What would happen if organisms with and without plasmids compete? I will give you a hint: this plasmid-bearing population can produce an allelopathic toxin that is lethal to its plasmid-free competitor, and yet, who wins?👉

1 month ago 0 0 0 0
Preview
Home - SEVA plasmids - Standard European Vector Architecture Standard European Vector Architecture 4.0 Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes WHAT…

⭕✨Standard, tailor-made, and send directly to your door food free. Too good can be true. Take a look at our website and check our vectors free of charge 👉

1 month ago 0 0 0 0

🦠✨This bacterium can act as a “sickness traffic light”. @ctropini.bsky.social and her group from the University of British Columbia have engineered a system in which cells that normally produce GFP reduce their fluorescence under stress conditions.
Discover the full story 👉https://shorturl.at/f9bpu

1 month ago 0 0 0 0

❓🦠With N, what is the main cause of foodborne illness? Non-typhoidal Salmonella! In it, plasmids enhance adaptability, combining resistance and virulence. Microbiota-targeted or CRISPR-based tools can provide opportunities to disrupt plasmid dissemination. 👉Check how:

1 month ago 0 0 0 0
Advertisement
Preview
Home - SEVA plasmids - Standard European Vector Architecture Standard European Vector Architecture 4.0 Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes WHAT…

Science anywhere? Absolutely yes! Science anyhow? No please! The #SEVA database of vector plasmids aims to improve Science replication and create a world in which high-quality science is available no matter where. Join us! 👉 seva-plasmids.com

1 month ago 0 0 0 0
Preview
A global soil plasmidome resource unveils functional and ecological roles of plasmids in soil microbiomes - Nature Communications Here, the authors report the Global Soil Plasmidome Resource, a comprehensive plasmid soil catalog, that explores the roles of plasmids in microbial adaptation and host integration, highlighting…

The @berkeleylab.lbl.gov presented the Global Soil Plasmidome Resource. A comprehensive dataset of 98,728 plasmid sequences amassed from 6860 terrestrial microbial communities and isolates. Check them out!👉 www.nature.com/articles/s41...

1 month ago 1 0 0 0
Preview
FIND YOUR PLASMID - SEVA plasmids - Standard European Vector Architecture Canonical SEVA plasmids that use Golden Gate assembly to build complex genetic circuits. Find your canonical plasmid In the dropdown menu below, you can select a combination of choice for your…

Replicable science requires shared standards. The #SEVA platform provides modular, standardized plasmid vectors that improve reproducibility and design. Explore the SEVA collection and order validated plasmids for free 👉 seva-plasmids.com/find-your-pl...

1 month ago 1 0 0 0
Preview
Beyond borders: plasmids drive a shared antibiotic resistome in European urban water systems - Microbiome Background Urban wastewater systems (UWSs) act as reservoirs and conduits for the dissemination of antibiotic resistance genes (ARGs), with plasmids playing a central role in their spread. Despite…

🌍🧬 Plasmids are spreading antibiotic resistance across European urban water systems.
A multi-omics survey found tens of thousands of plasmids carrying resistance genes, many previously unknown. It highlights how wastewater networks share and mobilize ARGs across borders 👉https://doi.org/qn2v

2 months ago 2 0 0 0
Preview
Comparative analysis of plasmid vectors used in gene editing and genetic engineering Plasmid vectors are foundational tools in gene editing and genetic engineering, enabling targeted genome modification, heterologous gene expression, and metabolic pathway optimization across diverse…

🧬📊 Read this comparative review of plasmid vectors used in gene editing and genetic engineering. It highlights how designing elements such as replication origin, host range, and CRISPR compatibility affect multiple features. How important it is to make the right selection? 👉

2 months ago 0 0 0 0
Preview
FIND YOUR PLASMID - SEVA plasmids - Standard European Vector Architecture Canonical SEVA plasmids that use Golden Gate assembly to build complex genetic circuits. Find your canonical plasmid In the dropdown menu below, you can select a combination of choice for your…

If you are a researcher working with plasmids, this is for you!👩🏾‍🔬🔬Standard, effective and ✨free✨, what else can you ask for? Take a look at our website and find your #SEVAplasmid ready to use 👉

2 months ago 0 0 0 0
Preview
A Versatile Plasmid System for Translational Control and Secretion of Recombinant Proteins in Mycobacteria Recombinant protein expression in mycobacteria faces two major challenges: limited regulatory tools for inducible expression and inefficient secretion of heterologous products. In this study, we…

🧬🔧 New tools keep emerging for mycobacterial protein production. This plasmid-based system enables translationally gated secretion in Mycobacterium, combining riboswitch control with highly efficient extracellular export. A new layer of regulation unlocked👉

2 months ago 2 0 0 0
Preview
Home - SEVA plasmids - Standard European Vector Architecture Standard European Vector Architecture 4.0 Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes WHAT…

A free, worldwide and standardized tool for researchers 🧑‍🔬🛠️ It seems too good to be true, but it exists! ⭕Our #SEVA plasmids accomplish all those characteristics to help scientific research succeed. Use them yourself! 👉

2 months ago 1 0 0 0
Preview
A therapeutic glue that autonomously targets gut bleeding in inflammatory bowel disease - Nature Biotechnology We engineered bacteria to function as therapeutic ‘living glues’ that autonomously detect gastrointestinal bleeding and, in response, secrete adhesive and therapeutic proteins to enable targeted…

🩸🩹You may have heard about using glue to stop bleedings. Maybe it is not the best strategy in the world, but scientists have engineered bacteria to function as therapeutic ‘living glues’ inside your body! 😳. Check how they do it 👉

2 months ago 1 0 0 0
Advertisement
Preview
Evolution of a Plasmid Regulatory Circuit Ameliorates Plasmid Fitness Cost Abstract. Plasmids promote adaptation of bacteria by facilitating horizontal transfer of diverse genes, notably those conferring antibiotic resistance. Som

⭕ Plasmids of the group lncP-1 replicate and usually persist in many bacteria, but nothing in nature comes without exception. The lncP-1𝛃 plasmid pBP136 became extinct in E.coli at the lab. Scientists from the @uidaho.bsky.social suspect which gene is guilty. 👉

2 months ago 0 0 0 0

🧬Plasmids are the workhorses of molecular biology, but are we really choosing them wisely? @vdlorenzo.bsky.social and Esteban Martínez-García revisit what really defines plasmid performance and why modular standards like #SEVA matter for the future of #SynBio 👉https://doi.org/10.1111/1751-7915.70273

2 months ago 1 1 0 0
Preview
CONTACT - SEVA plasmids - Standard European Vector Architecture Order plasmids If you wish to order SEVA plasmids, please fill in the form below. We offer this service pro bono so it is free of charge. Large orders ( > 15 plasmids) may experience shipment delays…

Have you already found your pSEVA plasmid match for your #SynBio project? You’re just one step away! 🚀

📤 Visit our website and choose the gateway to your next experiment—free, open, and ready to use 👉https://seva-plasmids.com/contact/

2 months ago 0 0 0 0
Preview
Engineering microbial consortia for mixed plastic upcycling - Nature Communications The chemical complexity of post-consumer ‘mixed’ plastic waste limits its use as a feedstock for biomanufacturing. Here the authors combine transition-metal-free plastic deconstruction with a…

♻️🦠Tackling mixed plastics! See the potential of engineered microbial consortia to upcycle complex mixed plastic waste. Integrating transition metal-free plastic depolymerization with the strengths of each bacterial specialist and division of labor 👇
doi.org/10.1038/s414...

2 months ago 2 0 0 0