How do you live longer? Your genes may help | CNN Scientists have long believed that longevity is shaped by lifestyle choices; however, a new study reveals that genes may play a larger role in determining how long people live.

www.cnn.com/2026/01/29/h...

Don't trust the CDC while RFK Jr. is in charge The HHS secretary, a notorious anti-vaxxer, is now posting his crank views on CDC's website

I can't stay quiet about what RFK jr is doing to the CDC and FDA:
stevensalzberg.substack.com/p/dont-trust...

earlier this year.

currently allowing carry-over

Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics Jiaqi Xie φ a, Phyo W. Win φ...

www.biorxiv.org/content/10.1...

Wow indeed. This is a disaster for U.S. science in so many ways. We're losing the future.

Reversible compromise of physiological resilience by accumulation of heteroplasmic mtDNA mutations Somatically acquired mitochondrial DNA mutations accumulate with age, but the mechanisms and consequences are poorly understood. Here we show that transient injuries induce a burst of persistent mtDNA...

Reversible compromise of physiological resilience by accumulation of heteroplasmic mtDNA mutations | Science www.science.org/doi/10.1126/...

One concern with using ChatGPT for scientific writing is that I find the process of writing itself can influence the final product. Having to articulate something precisely on paper may cause you to rethink your underlying assumptions and conclusions. I think this is particularly true for trainees.

Deleterious mitochondrial heteroplasmies exhibit increased longitudinal change in variant allele fraction Genetics; Cell biology.

New work from our group suggesting mitochondrial heteroplasmies are not just due to genetic drift:
Deleterious mitochondrial heteroplasmies exhibit increased longitudinal change in variant allele fraction: iScience www.cell.com/iscience/ful...

I signed. If you dislike what the Trump administration is doing to NIH and science, you should too.

I have signed this open letter

Donald Trump, RFK Jr, Jay Bhattacharya, Marty Makary, Vinay Prasad, Tracy Beth Høeg & the rest of the GOP science leadership is working hard & fast to dismantle the US biomedical enterprise & celebrating the destruction

Science is under siege from this kooky crowd

Harvard today, your institution tomorrow.

It's all part of the Project 2025 plan to destroy high education in America.

All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.

Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025

The Dangers of Raw Milk YouTube video by Dr. Glaucomflecken

youtube.com/shorts/CuSwN... I made some people big mad with this one

🧪 Ranking member Lofgren and 11 other House dems sent a fiery 7-page letter to acting NSF director today

"The cancelation of these awards suggests instead that NSF is willing to apply political censorship of awards under direction from President Trump and the DOGE teenagers"

Share widely #SaveNSF

Looking forward to the upcoming visit!

WHI Funding Announcement (April 21, 2025) Today, Women’s Health Initiative (WHI) investigators were informed that the Department of Health and Human Services (HHS) will terminate WHI Regional Center (RC) contracts at the end of their current fiscal year (September 2025). The WHI Clinical Coordinating Center (CCC) will continue operations until January 2026, after which time its funding remains uncertain. While written notification has yet to be received, investigators have been advised to expect formal confirmation soon.

This is an enormous loss: www.whi.org/md/news/whi-...

An image with a prescription pill bottle. Text on the image reads: 99% of all new medications resulted from federally-funded university research through NIH

Did you know? 99% of all new medications resulted from federally-funded university research through #NIH

Learn more about #ResearchSavesLives: hub.jhu.edu/research-sav....

‘Several dozen’ Johns Hopkins student visas revoked Days earlier, that number was closer to 12.

BREAKING: More international graduate students at Johns Hopkins University have lost their student visas. The total is now "several dozen," up from around 12. We are the first outlet to report on this, here is what you need to know:
www.thebaltimorebanner.com/education/hi...

Trump Officials Freeze $1 Billion for Cornell and $790 Million for Northwestern The funding pause amid civil rights investigations into both universities sharply escalates the Trump administration’s campaign against elite colleges.

University presidents, the time is now! Unshackle the general counsel's office! File all the lawsuits! Release the faculty upon the op-ed sections! Write to your alumni, parents, and donors! You have nothing to lose but a tiny percentage of your enormous endowments... www.nytimes.com/2025/04/08/u...

I hope we follow Princeton's example of fighting back when we are targeted (assuming it is just a matter of time...)

In Bloomberg interview, Eisgruber signals that Princeton will not make concessions University President Christopher Eisgruber ’83 signaled that Princeton would not make concessions to the federal government after news broke that the Trump administration had suspended dozens of the U...

I am proud to have Chris Eisgruber leading my university. He is meeting the moment.

‘One of the darkest days’: NIH purges agency leadership amid mass layoffs In shock move, four institute directors at the US biomedical agency are removed from their posts.

On health economist Jay Bhattacharya’s first day as head of the US National Institutes of Health (NIH), the chiefs of four of the 27 institutes and centres that make up his agency were removed from their posts.

https://go.nature.com/3QZ8GGT

Research Saves Lives. #shorts YouTube video by Johns Hopkins Bloomberg School of Public Health

Research Saves Lives.

Here at the Johns Hopkins Bloomberg School of Public Health research is about more than just data-it's about people.

Every future discovery starts with the work happening now. Read more about our research: hub.jhu.edu/research-sav...

youtube.com/shorts/q90oY...

Eric Green is out as head of National Human Genome Research Institute The longtime director of the National Human Genome Research Institute is stepping down, as the larger NIH braces for more changes.

Difficult to see how this helps human health or medical research. Eric has been an outstanding leader in our genomics community.

www.statnews.com/2025/03/17/t...

Keep big data in the fight against chronic diseases Cuts to NIH funding for biostatistical research would erode the United States' competitive edge, hindering the health, economy, and overall security of the nation

"A reduction in funding would erode the competitive edge my group has built over decades and will ultimately impact our capacity to make a difference in helping disease prevention in both individual—and population—levels," says @johnshopkinssph.bsky.social Distinguished Professor Nilanjan Chatterjee

Welcome! You are invited to join the following webinar: 2025 Westlake Science Symposia. After registration, you will receive a confirmation email with information on how to join the webinar. Mitochondria, the dynamic orchestrators of cellular energy metabolism and signaling, are essential guardians of health. Dysfunction in these organelles underlies a diverse array of pathologies, rangin...

Join me and Patrick Chinnery, Luca Scorrano, Aleksandra Trifunovic, and Min Jiang for the Westlake -
@science.org Online Symposium Wed 28 March 13.00 CET/20.00 China
Mitochondria in health and disease
us02web.zoom.us/webinar/regi...

Hey DC metro / NoVA / MD folks — let’s get this going!

David Broniatowski on LinkedIn: NIH has just announced that it will save $4 billion by capping university… | 61 comments NIH has just announced that it will save $4 billion by capping university indirect costs on federal grants. Will this actually save money? Bottom line: No. It… | 61 comments on LinkedIn

Please read and share this excellent FAQ on University indirect costs by my friend @broniatowski.bsky.social

He explains why these funds are essential and a critical investment for research in the United States.

www.linkedin.com/posts/david-...

The pointless destruction of the world's leading scientific and medical research system No one benefits from this

Powerful article written by my colleague Steven Salzberg that captures the damage being done to scientific research in this country:
stevensalzberg.substack.com/p/the-pointl...