Happy to share a new publication on Mechanistic Coupling of Enzyme Activities at the Replisome in JBC. We #Traklab compare and contrast strategies used across organisms to coordinate the many enzymatic processes that occur during DNA replication. Hope it is helpful. doi.org/10.1016/j.jb...

Enjoying Brisbane from TRI seminar to Felons brewery with Kum Kum Khanna and MathewJones.

9 days to go:
* 2 x open positions!
* Exceptional environment, competitive start-up package
* University of Toronto appointments
* Toronto has great (and peaceful) quality of life!

Happy to share new work from my lab by co-authors Peng and Lee-when BRCA1 is absent, RAD51 is busy authors.elsevier.com/sd/article/S...

No Kings On June 14—Flag Day—Donald Trump wants tanks in the street and a made-for-TV display of dominance for his birthday. A spectacle meant to look like strength. But real power isn’t staged in Washington. ...

www.nokings.org

UMASS Graduation-Congratulations Silvia!

Trump Has Cut Science Funding to Its Lowest Level in Decades The lag in funding extends far beyond D.E.I. initiatives, affecting almost every area of science: chemistry, computing, engineering, materials and more.

www.nytimes.com/interactive/...

Elegant study, congratulations!

Wrapping up an insightful conference on DNA Replication Gaps, Cancer, and Disease! 🎉 Congrats to our Future of Science Fund winners, Larissa Milano and @seppai99.bsky.social! Your achievements inspire us. 🌟 #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social

Three days, fresh data, & sparkly debates on how replication gaps drive cancer & disease. Grateful for every talk & discussion. Thank you for pushing science forward—next stop: great papers. Science moves fast when we move together! @albertociccia.bsky.social @labvincenzo.bsky.social

Looking forward to reading!

KSQA: Dr. Kyungjae Myung (DNA Replication Gaps) YouTube video by KeystoneSymposia

Submit poster abstracts by 4/3, 11:59pm MST for DNA Replication Gaps, Cancer, and Disease in Daejeon, South Korea. Join experts to explore DNA errors and cancer. keysym.us/KSDNARep25.

youtu.be/_aPIkDQg1rw #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social

Our latest article, in collaboration with Helle Ulrich, explores how the timing of lesion bypass and gap processing impacts genome stability.
doi.org/10.1093/nar/...

DNA Replication Gaps, Cancer and Disease Meeting Promo Join us at the Keystone Symposia on DNA Replication Gaps, Cancer and Disease, April 27-30, 2025, in Daejeon, South Korea with field leaders in DNA replication errors, DNA breaks, DNA repair and cancer! http://keysym.us/KSDNARep25 #KSDNARep25 IMPORTANT DEADLINES: Early Registration Deadline (Save $200): March 11, 2025 Poster Abstract Deadline: April 3, 2025 ___ Copyright Keystone Symposia, 2025. All rights reserved. About Keystone Symposia: Keystone Symposia is a 501(c)(3) nonprofit organization founded in 1972 that convenes 50-60 open, international scientific research conferences each year across the full range of the life sciences – from cardiovascular disease to immunology to neurobiology. The conferences accelerate life science discovery by bringing together and fostering collaboration among the world’s leading and next generation of research scientists. Visit Keystone Symposia at: https://www.keystonesymposia.org Visit Virtual Keystone Symposia at: https://virtual.keystonesymposia.org/ For more videos: https://www.youtube.com/user/KeystoneSymposia Follow us on Twitter: https://twitter.com/keystonesymp Follow us on BlueSky: https://bsky.app/profile/keystonesymposia.bsky.social Like us on Facebook: https://www.facebook.com/KeystoneSymposia Link to us on LinkedIn: https://www.linkedin.com/company/keystone-symposia-on-molecular-and-cellular-biology

Gaps may be small, but the meeting will be big! Come join us in South Korea!

Congrats Dirk!

I was very sad to learn of the passing of Mike Volkert, brilliant scientist always with kind smile...obit is posted www.umassmed.edu/maps/

Thanks Annabel!

Thank you, Patty!

Thanks Aura! looking forward to catching up at the Keystone meeting

Targeting BRCA1-deficient PARP inhibitor-resistant cells with nickases reveals nick resection as a cancer vulnerability Nature Cancer - Whalen et al. report that increased DNA end resection in BRCA-deficient, PARP inhibitor-resistant cancers leads to increased sensitivity to DNA nicks, limiting tumor formation in...

Congratulations to Jenna Whalen on her Nature Cancer paper out today-a distinct take on nicks and their toxicity! rdcu.be/d60Td

Please join the conversation and get your abstract in!

Groundbreaking, first ever meeting dedicated to DNA GAPS
📅 Save the Date: April 27-30, 2025 | Daejeon, South Korea www.keystonesymposia.org/conferences/...