Very pleased to share that our study “Noradrenaline causes a spread of association in the hippocampal cognitive map” is out in @natcomms.nature.com (my final PhD paper, only 3.5 years post PhD! 🙃)

Find the paper here: www.nature.com/articles/s41...

💥New paper out! Why do some people generalise threat more than others? We show that anxious people generalise more strongly, even after accounting for perceptual mistakes.

A huge (!) thanks to @ondrejzika.bsky.social @nicoschuck.bsky.social and @bernhardspitzer.bsky.social

Postdoctoral Research Fellow in Social Decision Neuroscience at University of Birmingham Explore an exciting academic career as a Postdoctoral Research Fellow in Social Decision Neuroscience. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

We are recruiting! Postdoctoral research fellow at www.sdn-lab.org, studying the computational & neural basis of social decision-making. Birmingham is a fantastic & affordable place to live, with one of the youngest populations in Europe & over 600 parks. Please share!
www.jobs.ac.uk/job/DQO275/p...

Over the years, I have written a few Jupyter/Rmd/Matlab notebooks that attempt to teach some statistical concepts, particularly in neuroimaging. You can find them here: www.mrc-cbu.cam.ac.uk/people/rik.h..., though I will say a bit more about each one in a number of posts over next few days.

❗️NEW OPINION PIECE 🗨

Want to find out how apathy might be more than evaluating cost and benefit? ⚖️ Then read on!

V excited for the release of my first opinion piece on #apathy as a failure of active inference in @cp-trendsneuro.bsky.social with thanks to my co-author @cambridgeftd.bsky.social 😊

Out now in Translational Psychiatry! www.nature.com/articles/s41...

Empathic disequilibrium: theoretical implications and clinical relevance Empathy is central to social cognition, yet efforts to link it with neurodiverse and clinical conditions have yielded contradictory findings, often reinforcing a deficit-focused narrative that conflic...

🧵 New paper! Five years ago, we, @fuzefovsky.bsky.social, Dr Alal Eran, and I, introduced empathic disequilibrium, the mismatch between cognitive and emotional empathy. In our article published in @cp-trendscognsci.bsky.social, we discuss the theoretical and clinical implications of the concept.

I updated a blog which I wrote a few years ago about PhD applications. There's a mix of reflections and practical tips which should be useful for anyone thinking about applying for a PhD (at predominantly UK institutions). Please share if it could be helpful! timothysandhu.github.io/blog/phd_blog/

Acetylcholine reflects uncertainty during hidden state inference To act adaptively, animals must infer features of the environment that cannot be observed directly, such as which option is currently rewarding, or which context they are in. These internal estimates,...

Congrats to Ella for her new paper! She asked a really interesting question about how the brain represents uncertainty during hidden state inference, and in a lovely crossover with theoretical work, she shows that in mice, acetylcholine dynamics play a crucial role. www.biorxiv.org/content/10.1...

This work is now out in Nature Communications! 🎉

Computational signatures of uncertainty are reflected in motor cortex excitatory neurochemistry: www.nature.com/articles/s41467-025-64702-6

Huge thanks to our amazing team! @beckyneuro.bsky.social @campsydept.bsky.social @camneuro.bsky.social

Long overdue update prompted by submitting my hardbound thesis: I successfully defended my PhD earlier this year and have started a postdoc with @beckyneuro.bsky.social! Excited for more adventures in uncertainty with an amazing team.

An interoceptive model of energy allostasis linking metabolic and mental health Interactions between metabolic interoception and regulation may drive comorbidity between mental and metabolic ill-health.

Mental and metabolic health are closely linked - but what drives this connection? In our new theory paper, we (w/ @camillanord.bsky.social & @hugofleming.bsky.social g.bsky.social) propose dysregulation of interoceptive energy allostasis as a key mechanism.
www.science.org/doi/10.1126/... 🧵 1/n

Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level).

If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...

so, so excited to share our new theory which endeavours to answer why depression and poor metabolic health go hand-in-hand: "An interoceptive model of energy allostasis linking metabolic and mental health" 💪🧠🔋 @saramehrhof.bsky.social
@hugofleming.bsky.social

osf.io/preprints/ps...