A nanopore-based HIV-1 reference epitranscriptome Abstract. Post-transcriptional modifications to RNA, which comprise the epitranscriptome, play important roles in RNA metabolism, gene regulation, and dise

New paper in *NAR*! 🧬
Nanopore-based HIV-1 epitranscriptome

Maps RNA modifications across full-length HIV RNAs → a field benchmark, including PLWH samples

Congrats to Li Zhang (co-first) from our lab, the Gagnon lab, and the whole team👏

🔗 tinyurl.com/3zup7t6t
#HIV #Epitranscriptomics #Nanopore

Viriatix!

🔬👨‍💻📰 #SReD is out!
Automated structural detection for #ImageJ & #FIJI, from nano to macro ✨🐘. No training data, no bias - texture analysis with GPU acceleration!⚡️
Brainchild of @afonsomendes92.bsky.social and adventure w @christlet.bsky.social lab + friends.

Check: www.nature.com/articles/s41...

Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration | mBio Human immunodeficiency virus (HIV) encodes a protein that forms a conical shell, called a capsid, that surrounds its genome. The capsid has been shown to protect the viral genome from innate immune sensors in the cell, to help transport the genome toward ...

@pitt-pmi.bsky.social PhD student Zac Ingram's @asm.org #mBio paper is out! His study shows that sequential binding of host proteins CypA and CPSF6 to HIV-1 capsid is required for optimal nuclear entry, integration, and infection. journals.asm.org/doi/10.1128/...

Good one!

🧠✨ Organoids + Microglia + HIV Inflammation = New insights! Our latest paper explores innate microglia development and HIV-induced inflammation in cerebral organoids. 🙌 Thanks to Al-Harthi, Lorenzo-Redondo & Schneider labs!

Dive in:
bit.ly/3EGWLKJ

Hmm o nanopyx consegue registrar em 3d também?