Congratulations Job!!!

The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍

Next-generation materials for nucleic acid delivery - Nature Reviews Materials Efficient and targeted delivery of nucleic acids is critical for realizing the full therapeutic potential of gene editing, vaccines and RNA-based drugs, and emerging delivery platforms offer innovativ...

Together with Roy Van der Meel , Hanadi Sleiman @sleimanh.bsky.social , Irene, Olivia Merkel, Paul Wender, Ali Miserez, Quentin Laurent and Paola Luciani @luciani-lab.bsky.social

Prof. Matt Harrington from McGill giving a beautiful CSC Award talk about the mechanisms that the mussels use to attach to surfaces. #CSC2025

UV-Cross-Linked DNA Nanomaterials Enable Robust Nanopatterning of Folate Ligands for Enhanced Cellular Uptake The arrangement of ligands on a nanomaterial scaffold is a powerful approach to enhance targeted cellular delivery. However, nanomaterial-mediated delivery often employs imprecise ligand conjugation, ...

New in JACS! We developed a DNA platform for targeted cancer therapy, using gentle UV light to “lock” nanostructures in place, with:

- Optimal ligand spacing for folate receptor (FR) binding
- Structural stability
- Enhanced delivery to FR-expressing cancer cells

📖 doi.org/10.1021/jacs...
#JACS

The McGillian nucleic acid chemists at Cesky Krumlov, Czech Republic!

I hope you feel better Jen!

Great opportunity!

Associate or Senior Editor (Organic Chemistry), Nature Communications Job Title: Associate or Senior Editor (Organic Chemistry), Nature Communications Organisation: Nature Portfolio Locations: Jersey City, London, New York, Philadelphia or Washington DC - hybrid working...

Nature Communications is looking to hire an organic chemist – more details in the link below #Chemsky #Chemjobs 🧪

Early-career reseachers at one of our Max Planck Institutes.

🚀 Apply now 🚀

The new Max Planck #Postdoc Program offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops.

postdocprogram.mpg.de
#ScienceCareer #PostdocProgram

Long oligos: direct chemical synthesis of genes with up to 1728 nucleotides The longest oligos that can be chemically synthesized are considered to be 200-mers. Here, we report direct synthesis of an 800-mer green fluorescent protein gene and a 1728-mer Φ29 DNA polymerase gen...

What impressive oligos syntheses! I am very excited by what this methodology can achieve for modified/alternative bases. Congratulations to the authors and their careful methodical work 🧪🧬 pubs.rsc.org/en/content/a...

Thank you so much Christophe! It’s an easy task with an exceptional scientist like you!

Our DNA cubes on instagram !congratulations Sinan Faiad Quentin Laurent and Alex Prinzen! www.instagram.com/reel/DE0IKCM...

Now that 2025 is here, just wanted to highlight the opening we have for an Organic Chemistry Lectureship at St Andrews again.

Applications close in about two weeks on 22nd January. All the details in the link.

www.vacancies.st-andrews.ac.uk/V2/ViewVacan...

Sequence-Defined DNA Polymers: New Tools for DNA Nanotechnology and Nucleic Acid Therapy ConspectusStructural DNA nanotechnology offers a unique self-assembly toolbox to construct soft materials of arbitrary complexity, through bottom-up approaches including DNA origami, brick, wireframe,...

Review just out! Our 10-year journey with sequence-defined DNA polymers: new self-assembly concepts and advances in #NucleicAcidTherapy. Anisotropic and DNA-printed structures, modified aptamers, precision gene silencing, we share our passion for these molecules! pubs.acs.org/doi/10.1021/...

Heartbroken by the loss of Sir Fraser Stoddart, a true giant in chemistry, a personal inspiration, and a strong supporter of the supramolecular community. His brilliance, kindness, and legacy will continue to inspire us.