Congratulations to @melinamessing.bsky.social for receiving this prestigious award to support her research on polycystic kidney disease in my lab. And many thanks to the @pkdfoundation.bsky.social and @asnkidney.bsky.social for the support!
Posts by Thomas Weimbs, PhD
Congratulations to @melinamessing.bsky.social for receiving this prestigious award to support her research on polycystic kidney disease in my lab. And many thanks to the @pkdfoundation.bsky.social and @asnkidney.bsky.social for the support!
Congratulations to @melinamessing.bsky.social for receiving the 2025 Jared J. Grantham Research Fellowship Award to study "Immune Mechanisms Underlying Efficacy of Ketogenic Metabolic Therapy in Polycystic Kidney Disease" in my laboratory.
Details here:
www.kidneycure.org/pages/qa.asp...
It has already been shown in animal studies how BHB improves glomerular structure and function. That part isn’t a mystery anymore 😀
Remission of chronic kidney disease is possible with ketogenic metabolic therapy.
Remission? Yes, remission!
2 year follow-up study in diabetic nephropathy just published.
doi.org/10.3389/fnut...
Excellent article summarizing the state of knowledge on ketogenic metabolic therapy for CKD and ADPKD.
--> Every nephrology professional should be aware of this
link.springer.com/article/10.1...
Please forward to your Spanish-speaking friends & family with polycystic kidney disease
If anyone happens to be in Bangkok on Thursday, you are welcome to join my seminar: "Disease-Modifying Therapy of Polycystic Kidney Disease with Nutrition and Lifestyle Interventions"
"...all foods can be shown to both cause and prevent cancer"
Love this commentary pointing out how a lot of the nutrition "science" literature is complete crap. That's how we ended up with generations of dietitians and MDs learning things backwards!
www.degruyter.com/document/doi...
Curious about how people with ADPKD can improve their health in a nutrition & lifestyle program?
Video just posted...
Impressive outcomes with ketogenic therapy for an "untreatable" form of brain cancer
www.frontiersin.org/journals/nut...
"Therapeutic Potential of Ketogenic Interventions for Autosomal-Dominant Polycystic Kidney Disease: A Systematic Review"
--> Bottom line: Only beneficial outcomes
--> When does it become unethical to withhold info on this alternative from patients?
www.mdpi.com/2072-6643/17...
Ketogenic therapy in chronic kidney disease, stage 3-4
~54 weeks
-> Reduced BMI, HbA1c
-> Improved kidney function (creatinine, BUN)
-> Deprescription of diabetic and BP medication
-> No safety concerns
journalofmetabolichealth.org/index.php/jm...
Ketogenic Diet for Polycystic Kidney Disease?
What is the evidence? Excellent talk by Australian nephrologist Dr. Alok Gupta.
youtu.be/37Ov8qM-9Co
Discussion about the Ren-Nu nutrition & lifestyle program for people with polycystic kidney disease.
How to get started?
How the PKD-Free Alliance helps families with polycystic kidney disease to conceive PKD-free babies.
youtu.be/SOdkBI1M7u8
If anyone still believes in protein restriction for kidney disease, take a look at this article.
www.scielo.br/j/jbn/a/MDWX...
@kidneyboy.bsky.social @hswapnil.medsky.social
The English Version: My dad’s incredible journey to improving and maintaining kidney function—after transplant! He implemented KMT post-transplant to support his health. His story challenges the norm and shows the power of nutrition.
Yes, nutrition matters, even post-transplant!
Ketogenic lifestyle AFTER kidney transplantation to help maintain kidney function?
Find out what happened to Manfred, who has polycystic kidney disease:
youtu.be/o_3oXym5-pw
Important study!
A multimodal telemedicine intervention not only greatly improves the health of participants but also saves a self-insured company a lot of money
www.frontiersin.org/journals/nut...
My dad’s incredible journey to improving and maintaining kidney function—after transplant! He has PKD and implemented ketogenic metabolic therapy post-transplant to support his health. His story challenges the norm and shows the power of nutrition.
Yes, nutrition matters, even post-transplant!
Low-carb diets win against low-fat diets (except in most important measure):
- reduce HbA1c, fasting glucose, and triglycerides 💪
- superior weight loss 💪
- increased HDL 💪
Big problem: reductions in diabetes medication!
--> No money to be made 😭
doi.org/10.7759/cure...
Ketogenic diet AFTER kidney transplantation. Wait, what? Why?
Manfred has polycystic kidney disease and implemented ketogenic metabolic therapy AFTER transplantation to maintain his renal function.
In German. English version coming up, stay tuned.
youtu.be/5OTUbvjh7ng
I am thrilled to work even more closely with Dr. Shigeo Horie!
New paper alert! 🚨 Not what we expected.
In @emboreports.org, we show eosinophils & STAT6 have a negligible role in muscle regeneration & DMD—contrary to prior research.
Negative data matters. It moves science forward. 💡🔬
www.embopress.org/doi/full/10....
The Ren-Nu renal nutrition program for individuals with POLYCYSTIC KIDNEY DISEASE will soon be re-launched.
Brief discussion and preview with @melinamessing.bsky.social and @weimbs.bsky.social
youtu.be/XmCR05SGdgo
@weimbs.bsky.social talks with NightmareRH about his journey with polycystic kidney disease (ADPKD). Chris was diagnosed without a family history and told that there is nothing he could do, and that he would eventually need to be on dialysis and require a kidney transplant.
--> youtu.be/Vlxl7ZmZPSA
Useful grocery shopping list for people with mild to moderate kidney disease (and other Homo sapiens who want to avoid kidney disease)
- Low Carb (sugars, starch)
- Low Oxalate
- Whole Foods Only
- No Ultra-Processed Foods
--> Download here:
santabarbaranutrients.myshopify.com/pages/shoppi...
Agreed. It's time to stop the protein-restriction nonsense in early CKD. First, do no harm!
If a compelling, long-term RCT demonstrates a clear benefit of protein-restriction, we can talk. The burden of proof is on the intervention. The proof is missing, and has always been missing.