Explore our Newsroom for expert insights on automated sample preparation. 🧪

From deep-dive application notes, new publications, interviews, to the latest in LC/MS and GC/MS workflows, find the resources you need to optimize your lab.
Read more: https://www.palsystem.com/en/newsroom/

Comparison of solid phase microextraction coatings for headspace extraction of volatile perfluoroalkyl substances using one-dimensional and comprehensive two-dimensional gas chromatography Volatile and semi-volatile per- and polyfluoroalkyl substances (PFAS) represent an important, yet analytically challenging subset of emerging contamin…

This study highlights that advanced automation and multidimensional chromatography are essential for a complete picture of PFAS in our environment.
Read the full study here:

New research alert! 🧪Automated SPME Arrow on the PAL System captures 15 volatile PFAS classes at ng L⁻¹ levels. HLB/PDMS sorbents show a 706 % higher response for 4:2 FTOH. Solvent-free and precise. 🏹

Analytica 2026 was a blast! 🥨 From Munich to the lab: the new PAL Pipette Tool with LLD and FlipTube handling stole the show. Plus, the feedback on PAL Method Composer 2.0 + AI was 🚀.

Catch the webinar series here: palsystem.com/en/newsroom/news/pal-met...

Day 2 at analytica 2026! 🚀 Watch our Day 1 recap and join us at booth A1.327 for live demos of automated sample prep. 🧪

Why is so much research lost to technical noise? Because precision starts with the sample, not just the detector. 🧪 Watch our brand video to see how we’re redefining the pre-analytical phase. 📽️

🎧 WATCH WITH AUDIO ON!

PAL System at analytica 2026 | PAL AI & Cloud Lab Automation Visit PAL System at analytica 2026 (Booth A1.327). Explore the new web-based PAL Method Composer, interactive PAL AI Assistant, and specialized PFAS Upgrade Kits.

Read the full preview in our Newsroom:

Automation is no longer just about moving samples. It is about the integrity of every data point. As we head to Munich, PAL System is moving toward a unified ecosystem where software and hardware act as one.

📍 Visit us: Anayltica Hall A1, Booth 327

Green Food Safety: Reducing LC Solvent Waste by 25-Fold <p>The analytical requirements for pesticide residue monitoring in food continue to grow. Laboratories today face the dual challenge of increasing sensitivity for regulatory compliance while also striving for more sustainable, "greener" laboratory practices. A recent study published in <i>Food Chemistry</i> by Jesús et al. (2026) demonstrates a significant step forward by coupling micro-flow liquid chromatography with Q-Orbitrap high-resolution mass spectrometry (HRMS).</p>

Read the Newsroom Article:

"This greener approach reduces solvent consumption and waste by 25-fold." 🌿

Recent research shows how micro-flow LC-HRMS and automated cleanup with the PAL RTC make food safety more sustainable. High-performance science with a smaller footprint. 🧪

We are happy to welcome Rachael Szafnauer from Markes International as our very first guest writer for the PAL System Newsroom! 📖 www.palsystem.com/en/newsroom/news/from-br...

📅 Visit us at analytica 2026: Hall A1, Booth 327

Get a head start on the innovations shaping the future of sample preparation.
Read our latest Newsroom preview here:
www.palsystem.com/en/newsroom/news/pal-sys...

PAL System Gold Smart Syringe Improve MS sensitivity with the PAL System Gold Smart Syringe. Features a gold plunger for superior inertness, reduced carryover, and 3x longer lifetime. Ideal for bioanalysis, toxicology, and water analysis.

When your hardware is built to last, you can spend less time on maintenance and more time on the science that matters.

See how our new syringe can support your lab:

Why settle for standard when your lab can have the gold standard? 🏆
In high-throughput chromatography, the syringe plunger is often the first thing to fail. Mechanical wear from thousands of injections leads to leaks, carryover, and downtime.

We are excited to announce our participation at analytica 2026 in Munich!
As your partner in ingenious sample handling, we invite you to explore how our automation platform facilitates analytical accuracy and laboratory efficiency.

Metabolomics at Heidelberg University <p>In our very first interview, Dr. Poschet provides valuable perspectives on the current state and future directions of metabolomics.</p> <p>He discusses the challenges and rewards of managing a core facility, the importance of automation and rigorous quality control, and the evolving role of metabolomics in precision medicine and multi-omics research.</p> <p>We would like to thank Dr. Poschet for taking the time and answering our questions.</p> <p>Find out more about the core lab and its services&nbsp;<a href="https://www.cctp.uni-heidelberg.de/en/core-facilities-and-technology-development/metabolomics-core-technology-platform" target="_blank">here</a>.</p> <p>See how they automate their metabolomics workflows <a href="t3://file?uid=5690">here</a>.</p>

Read more about GC/MS and Metabolomics in this Interview

Download the App Note

Manual GC/MS batches lead to variable wait times, causing Glutamine to cyclize and Tryptophan profiles to shift.
Our App Note with the MCTP Heidelberg shows how automated overlapping ensures identical reaction histories for every sample.

A Conversation with Madison L. Williams on Volatile PFAS and Automated Microextraction <p>We often refer to PFAS as "forever chemicals," but this label misses a critical dynamic: the "forever cycle." While regulatory efforts focus on removing persistent ionic compounds from our water and soil, a hidden reservoir of volatile "neutral" precursors circulates in the air. These mobile molecules travel unseen, eventually degrading and transforming back into the very ionic PFAS we are trying to eliminate—continuously replenishing the pollution supply.</p> <p>Breaking this cycle requires catching these "slippery" airborne precursors before they transform. To do that, researchers need precise, robust, and automated analytical workflows capable of trapping volatile compounds without losing them.</p>

Read the Q&A:

Volatile neutral precursors (FTOHs, FOSAs) circulate in the air, unseen, before transforming back into ionic PFAS.

Madison L. Williams explains why standard methods miss them and how automated SPME Arrows close the gap. 🏹

2026 is here! 🌍 Ready to optimize your GC/MS or LC/MS workflows?

We are hitting the road! First major stop: analytica 2026 in Munich. 🇩🇪

Check out our full travel itinerary to see where we can connect this year: www.palsystem.com/en/newsroom/news/meet-pa...

Stuck tool on your PAL RTC?
If a bent plunger prevents automatic parking, don't force it. We created a quick guide on how to perform a manual tool removal and mount safely.

Watch the full Step-by-Step here: https://www.youtube.com/watch?v=Noxy7_3gx3E

#LabAutomation #PALSystem #Troubleshooting

Discover how this technique is pushing the boundaries of trace-level analysis in our latest article.
👉 Read more: palsystem.com/en/newsroom/news/v-itex-launched/
#SamplePreparation #MassSpectrometry #AnalyticalChemistry #ITEXDHS #GreenChemistry

By applying a vacuum to the sample vial during extraction, Vacuum-ITEX (V-ITEX) effectively lowers the pressure, increasing the volatility of analytes without the need for excessive heat.

When analyzing semi-volatile organic compounds (SVOCs), increasing extraction temperature isn't always an option due to analyte degradation. A noteworthy advancement in ITEX DHS technology addresses this challenge through vacuum assistance.

Our PAL newsletter delivers key developments in automated sample preparation, curated from our Newsroom, directly to your inbox. Stay informed on the future of automated sample preparation. Subscribe here: https://www.palsystem.com/en/pardotform/

Happy Holidays! ❄️🔬
Thank you for trusting us with your sample preparation in 2025. We look forward to automating more discoveries with you in the year ahead.

Our showroom transformed into a studio with the PAL DHR (Dual Head) taking center stage. 🤖
It is fascinating to watch the two heads work independently to optimize throughput, turning a busy sequence into a smooth, synchronized performance. We can't wait to share the final video!

Our new application note, "Tackling Forever Chemicals in FCM" details a complete walk-away solution for volatile PFAS.
See the full workflow for yourself. Download the application note: www.palsystem.com/index.php

How is automation evolving to meet today’s biggest analytical challenges?

Our newsletter curates the latest insights from our Newsroom, focusing on developments in automated sample preparation, but also goes beyond that!