Whatβs the connection between sleep disruption, the choroid plexus, and brain aging? Find out at my #SfN25 poster where Iβll be sharing new data from the IGNITE study!
Tuesday 11/18, 8AM-12PM
πSession C.02, LBP070.20
#Neuroscience #SleepPeeps
Posts by Miranda Chappel-Farley, PhD
These findings provide insight into a potential mechanism underlying the heterogeneity in the insomnia-cognition literature; whether older adults have a distinct active and sleep period may be a determinant of whether cognitive impairments arise!
Some key highlights:
π€ Older adults with insomnia exhibited dampened RARs with greater activity during the rest period
π§ More robust and stable RARs were associated with better attention performance, irrespective of insomnia diagnosis
π£ Excited to share our new short report published in JSR! We examined whether older adults with insomnia exhibited differences in rest-activity rhythms (RARs) and cognition, and whether RARs were associated with cognition across domains
onlinelibrary.wiley.com/doi/10.1111/...
Very excited to share the final publication from my dissertation! Using a graph theory approach, we found that differences in medial temporal lobe functional network organization were tied to memory processing and sleep oscillations implicated in consolidation!
academic.oup.com/sleep/advanc...
Thank you!
Thanks so much Matt! Means a lot! π
Over the past few years, Iβve shared my personal journey as a sleep scientist living with sleep apnea with other scientists and students to raise awareness and reduce stigma. Iβm excited to reach an even broader audience in my recent interview with Parade π
parade.com/health/i-fel...
Now out in Sci Rep! We found that physical activity was associated with better memory consolidation during sleep and that theoretically replacing 30m of lower intensity activity with moderate intensity physical activity yielded a significant consolidation benefit!
www.nature.com/articles/s41...
Would love to be added please!
π’ New preprint! We used network neuroscience techniques to probe central tenets of memory consolidation theory (particularly during sleep)! TL;DR Intrinsic measures of network integration and MTL centrality are tied to sleep oscillations and each phase of emotional memory processing π§