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Posts by Patrick MacDonald🇨🇦

(🧵1/23) First month of 2026: complete✅! Many papers coming from CIRTN scientists, including works from the labs of Drs Bruin, Lynn, Estall, Ferdaoussi, Fullerton, Hull-Meichle, Pepper, Korbutt, Levings, Lim, Mulvihill, Rabasa-Lhoret, Riddell, Rutter, Tsai, Woo and Verchere! 📝

2 months ago 9 10 1 0

After the World Trade Center was attacked (just four miles from Trump Tower), more than 40,000 Canadians in uniform fought alongside their U.S. allies in Afghanistan.

More than 2,000 Canadians were wounded.

These 158 didn't make it home.

And now this guy is giving lectures on gratitude.

2 months ago 1094 459 50 22

Take a look behinds the sciences of our recent work!

4 months ago 6 3 1 0
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Behind the Scenes: Featuring authors Theodore dos Santos, Xiao-Qing Dai, Patrick E. MacDonald, James G. Lyon, Aliya F. Spigelman, Nancy Smith, Tina Dafoe, and Austin Bautista and their work with IsletCore

4 months ago 5 2 0 1
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What can surviving pancreatic cells tell us about type 1 diabetes?

Patrick E. MacDonald @bcellorg.bsky.social analyze pancreatic islet cells from donors with type 1 diabetes, defining pathways and mechanisms responsible for altered insulin and glucagon: doi.org/10.1172/JCI1...

4 months ago 5 2 1 1

Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes @jci.org @bcellorg.bsky.social @ualberta.bsky.social #T1D
www.jci.org/articles/vie...
www.jci.org/articles/vie...

4 months ago 7 2 0 0
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An integrated analysis that combines electrophysiological and transcriptomic profiling, along with machine learning, of #islet cells from #T1D donors highlights the importance of α cell dysfunction @albertadiabetes.bsky.social @jci.org @bcellorg.bsky.social www.jci.org/articles/vie...

4 months ago 8 6 0 0
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#1 Islets in a Pod with Dr. Patrick MacDonald
#1 Islets in a Pod with Dr. Patrick MacDonald YouTube video by CIRTN-R2FIC

CIRTN-R2FIC is currently running in Toronto its 4th Annual Meeting. During this meeting we have launched our mini interview series called "Islets in a Pod" ! Our first interview is with Dr. Patrick MacDonald from the University of Alberta.
youtu.be/UlHn_1Fz3ck?...

4 months ago 18 14 1 1
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It was a pleasure to attend the @cirtn.bsky.social workshop. I could not be more impressed by the incredible trainee presentations. And it was a special pleasure to present the first CIRTN Science Communication Award to three amazing scientists: Lahari Basu, Maria Galipeau and Cassandra Locatelli!

4 months ago 10 5 0 0

Unfortunately can’t be there in person this year, but wishing everyone attending @cirtn.bsky.social national meeting a good time in Toronto!

4 months ago 3 0 0 0

🧵(1/12) November is Diabetes Awareness Month, and we have many works coming out from the CIRTN labs focusing on islet biology and diabetes. For the beginning of Nov 2025, we have papers from Drs Thompson, Verchere, Chen, Dhanvantari, Hill, Hoesli, Kin, Levings, Lynn, Riddell, Rutter and Wheeler.

5 months ago 12 7 1 0

'Icicle kick' goes viral: CPL final tops 1 billion views

www.theglobeandmail.com/gift/aaa9fec50b2b595cc02...

5 months ago 1 1 1 0
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Canada Is About to Lose Its Status as Having Eliminated Measles

“The New York Times found that at critical points, as measles was gaining new footholds in Canada, provincial politicians stopped public health officials from speaking out about the value of getting vaccinated”

www.nytimes.com/2025/11/06/w...

5 months ago 5 1 0 0
Robert Munsch donates his archives to Guelph Public Library Robert Munsch donates his archives to Guelph Public Library

Robert Munsch has donated his personal archives of stories and materials to the Guelph Public Library.

This is wonderful for such a valuable archive to be given to a public municipal library.

www.guelphpl.ca/Modules/News...

5 months ago 217 38 3 4
Canadian Federal Budget 2025 Part 1
Canadian Federal Budget 2025 Part 1 YouTube video by Higher Education Strategy Associates

Budget analysis part 1

5 months ago 6 4 0 0

www.theglobeandmail.com/gift/aaa9fec50b2b595cc02...

5 months ago 3 3 0 0
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How much are MPs entitled to know about research grants? Not as much as you think. - Globe and Mail

5 months ago 4 5 1 0
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🧵(1/4) We have finished up October 2025 🎃, and the CIRTN groups had several more publications coming from the labs of Drs Rennian Wang, Megan Levings and Marc Prentki.

5 months ago 7 2 1 0

This! Fancy web interfaces let you explore the data, but they are not the same as sharing the data. You can do both!

5 months ago 8 4 0 0
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Open Letter to Protect Tri-Council EDI Data Why do we need urgent action to protect our data? The mandate of the House of Commons Standing Committee on Science and Research is to review and report on topics relating to science and research in ...

If you are a Canadian scientist interested in the protection of identifying information about applicants and reviewers of tricouncil grants please read and sign this letter. Thank you. docs.google.com/forms/d/e/1F...

5 months ago 7 6 1 1

📢 Support Our Science in the news!

We’re proud to be featured in CTV News’ latest story on Canada’s emerging “brain gain” — a scientific migration as researchers look north amid challenges in the U.S.

5 months ago 11 6 2 0

Doesn’t EGA have a node in Sweden specifically for controlled access sharing of this type of data?

https://fega.nbis.se

6 months ago 1 0 0 0

Interesting paper, but does anyone know if the claim that “…The datasets (genome-wide raw sequencing and individual-level clinical data) … are not publicly available due to EU and national legislation” is reasonable?

https://www.nature.com/articles/s41598-025-21595-1

6 months ago 1 0 1 0

🧵(1/4) For the first half of October 2025 we have 3 publications from the CIRTN labs🍁. These papers are from the groups of Drs. Bruce Verchere, Yi-Chun Chen, Francis Lynn, James Shapiro, Tatsuya Kin and Guy Rutter!

6 months ago 9 5 1 0
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@lukaszukab.bsky.social on Bluesky #ForeverCanadian crew is set up by the pumpkin weighing station (near the museum) at the Smokey Lake pumpkin festival. 🎃 Come on over and sign the petition, please! 🇨🇦
6 months ago 1 0 0 0
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Today, #ForeverCanadian brought 230,000 petition signatures to Edmonton. Our volunteers will continue collecting signatures until October 28. We need your signature to reach our 300,000 requirement to keep Alberta in Canada.

#ableg #Yeg #Yyc #CdnPoli

6 months ago 301 145 12 24

🧵(1/7)We are now out of September🍁! From the last two weeks we have had publications from the CIRTN labs of Drs Jenny Bruin, Mourad Ferdaoussi, Peter Light, Patrick MacDonald, James Shapiro and Bruce Verchere!

6 months ago 14 8 1 0
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Novel insights into the molecular underpinnings of islet cell dysfunction in #T1D highlighting pathways that may be leveraged to preserve residual β-cell function and modulate α-cell activity @bcellorg.bsky.social www.jci.org/articles/vie...

6 months ago 32 9 1 0

And a special thank you to the organ donors, and organ procurement organizations and coordinators across the country (BC Transplant, Alberta Health Services / Give Life Alberta, Ontario Health / TGLN, Quebec Transplant, MOTP Atlantic Canada).

6 months ago 3 0 0 0

Over the past, nearly 15 years, our team has isolated more than 140 million pancreatic islets in support of diabetes and transplantation research across three continents.

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