Excited to see our study on antenatal #melatonin for #cardiovascular deficits in FGR highlighted by @jphysiol.bsky.social 🫀💊
The findings paint a nuanced picture, melatonin may offer protection, but it’s not uniform, highlighting the importance of understanding therapies fully in large animal models

@clinicalscience @monashuniversity.bsky.social @hudsonresearch.bsky.social

In vivo and ex vivo cardiovascular haemodynamic responses of preterm growth-restricted lambs to perinatal asphyxia - PubMed Fetal growth restriction (FGR) arises from chronic hypoxia and increases the risk of cardiovascular dysfunction following perinatal asphyxia, although underlying mechanisms remain unclear. We investigated whether cardiovascular responses to asphyxia are impaired in preterm FGR lambs and whether this …

New paper from Dr Zahrah Azman et al. shows preterm growth-restricted lambs with asphyxia have impaired vascular contractility and heightened cardiac adrenergic responses, insights that matter for neonatal cardiovascular outcomes. Read & share 👇 pubmed.ncbi.nlm.nih.gov/41432623/ #FGR #CardioSci

A reduction in large animal research threatens the perinatal translation research pipeline - Pediatric Research Pediatric Research - A reduction in large animal research threatens the perinatal translation research pipeline

Physiology can’t be shortcut, and losing these models risks future neonatal care. @pediatricresearch.bsky.social
www.nature.com/articles/s41...
#PerinatalResearch #NeonatalScience #DiscoveryScience #TranslationalResearch

A reduction in large animal research threatens the perinatal translation research pipeline - Pediatric Research Pediatric Research - A reduction in large animal research threatens the perinatal translation research pipeline

New Ped Res paper from collaborators across four countries examines the weakening of the perinatal translation pipeline due to the global decline in large-animal research.

Aaaahhhhh, that’s a sign it time for holidays

@monashuniversity.bsky.social @hudsonresearch.bsky.social

Honoured that our team Prof Sehgal and Zahrah Azman received a @heartfoundationau.bsky.social Vanguard Grant for our work that aims to reduce peri vascular fibrosis in the hearts of growth restricted neonates. Working towards the best start to life possible for our smallest most vulnerable babies.

The is all laying the scene for Brad and Amber I fear

@jphysiol.bsky.social
@monashuniversity.bsky.social
@hudsonresearch.bsky.social

The cardiopulmonary transition at birth is often compromised in infants with fetal growth restriction (FGR) or born small for gestational age (SGA).

Early detection of myocardial stress & pulmonary dysfunction could be key to better outcomes.

#FGR #SGA #cardiology #neonatology #research

Compromised cardiopulmonary transition in fetal growth restricted and small for gestational age neonates Abstract figure legend Differences in cardiovascular function between appropriately grown (AG) and fetal growth restricted (FGR) infants after the cardiopulmonary transition at birth. AG infants typi....

NEW PAPER

Compromised cardiopulmonary transition in fetal growth restricted and small for gestational age neonates

Suboptimal fetal growth → altered cardiac structure/function → higher risk of impaired adaptation at birth, respiratory morbidity, and long-term CV risk.

doi.org/10.1113/JP28...

New paper from our team:

Pathogenesis of Preterm Intraventricular Haemorrhage
karger.com/dne/article/...

We review the maturational profile of cerebrovascular development in the preterm neonate.

@hudsonresearch.bsky.social @bethjallison.bsky.social

@monashuniversity.bsky.social
@hudsonresearch.bsky.social
@atulmalhotra.bsky.social

Pathogenesis of Preterm Intraventricular Haemorrhage Abstract. Background Intraventricular haemorrhage (IVH) is the primary neuropathology in infants born very preterm. IVH describes bleeding into the ventricular space of the newborn brain, originating ...

Excited to share our latest paper on the pathogenesis of preterm intraventricular hemorrhage. Our study sheds new light on the complex interplay between the contribution of fetal and maternal factors. Check out the full paper to learn more about the important findings! karger.com/dne/article/...

That’s awesome -Abdul!! Congratulations

Yes!!!! Trying to make it stick :)

Me too!

Really looking forward to meeting all the students involved in the SRI INSPIRES at the congress in Charlotte! @sriwomenshealth.bsky.social

The Education Hub - Conversation with the experts Education Podcast · 123 Episodes · Updated Monthly

In this podcast, ahead of World Kidney Day 2025, I discuss why preterm birth and post-natal kidney injury can lead to increased mild kidney disease risk in adulthood. Early detection and treatment can reduce progression.

www.podbean.com/ew/pb-zr9r3-...

Women earn 78 cents for every $1 men paid on average New data shows Australia's gender pay gap has narrowed, but working women are still more than $28,000 a year worse off than the average man.

I am thankful to work in a very supportive female led workplace, but it can still feel like trying to work with one hand behind your back.

There has been some improvements but the gender pay gap remains.

www.abc.net.au/news/2025-03...

😳

In this cohort study, PISCOPO et al. analyze data from the the Australian and New Zealand Neonatal Network (ANZNN) to investigate the relationship between birth weight and IVH in very preterm neonates @atulmalhotra.bsky.social
buff.ly/4hKcIhH
#neosky #neoEBM #EBNEOalerts

The interplay between birth weight and intraventricular hemorrhage in very preterm neonates – a retrospective cohort study Intraventricular hemorrhage (IVH) most commonly occurs in infants born very preterm (<32 weeks’ gestation). There are mixed findings on whether infant…

In work completed by my fabulous PhD student Beth Piscopo, we undertook a large retrospective cohort study showing in very preterm infants the presence of SGA or suspected FGR is associated with a reduced rate of IVH, compared to infants without SGA/FGR.

www.sciencedirect.com/science/arti...

Leadership

I am wondering about my upcoming conferences in USA too? Firstly for boycot reasons and now because air travel seem much less safe there!

Fetal growth restriction adversely impacts trajectory of hippocampal neurodevelopment and function - PubMed The last pregnancy trimester is critical for fetal brain development but is a vulnerable period if the pregnancy is compromised by fetal growth restriction (FGR). The impact of FGR on the maturational...

Our first 2025 pub shows that growth restricted fetuses have significantly reduced dendrite outgrowth in hippocampal neurons. Reduced dendritogenesis in FGR offspring has implications for the development of hippocampal connectivity and long-term function.

pubmed.ncbi.nlm.nih.gov/39780443/

So well deserved @drabdulrazak.bsky.social. Congratulations

Thrilled to contribute to this groundbreaking work on cell therapy, where we successfully demonstrated that a targeted dose of stem cells can be obtained from extremely preterm infants and safely reinfused

www.thelancet.com/journals/ebi...
#neoEBM
@atulmalhotra.bsky.social

Breaking: doctors starting to suspect that women's bodies work differently than men's REGINA, SK - In a groundbreaking speech, Dr. Jeremy Edgar of Fairmont Grover Health Research Institute, delivered new findings that the female body may have innate biological differences than male bod...

Breaking: doctors starting to suspect that women's bodies work differently than men's