Subgroup of meningiomas involving FOS and FOSB gene fusions - Nature Communications Approximately 17% of meningiomas remain genomically uncharacterized. Here, the authors analyze 105 meningiomas without known driver mutations or significant copy number alterations and identify a subg...

Happy to share that our latest paper is published at @natcomms.nature.com . We’ve identified a novel subgroup of meningiomas defined by recurrent fusions in the FOS/FOSB genes, expanding the molecular classification of meningiomas. Read it at : www.nature.com/articles/s41... . #Meningioma

Tumor-initiating genetics and therapy drive divergent molecular evolution in IDH-mutant gliomas Astrocytomas and oligodendrogliomas are slow-growing and treatment-sensitive IDH-mutant gliomas diagnosed at ages 30-50. Local tumor regrowth and treatment resistance is inevitable resulting in 3-10 y...

New preprint on longitudinal treatment response signatures in IDH-mutant glioma from the GLASS Consortium www.biorxiv.org/content/10.1...