Doing lipids on previous gen of orbitraps with HCCT/narrow aperture funnel is a pure fun and joy. Especially looking at that cholestadiene peak in NL 1e8 range. So, who are lucky enough to have these machines and unlucky enough to do small molecules - set your RF to max 20% (this spectrum 40)
Metabotims?
Our recent delivery for those in lipidomics community needing faster methods or dealing with buiky species. Enjoy!
www.sciencedirect.com/science/arti...
tuna break
Lipids from 200 nL of breast milk sample with M3/IQX. Total 942 hits after removal of generic crap.
Not bad, but the problem is narrow inlet of IQX. Badly want to acquire the same thing on Ascend with HCCT.
orbitrapping deep lipidomics at UNIL metabolomics platform with Julijana Ivanisevic
Our microflow-mnESI lipidomics article is finally out in Analytical Chemistry. For all those who wants better coverage, sensitivity or works with limited sample amounts.
Next chapter coming soon, stay tuned!
doi.org/10.1021/acs....
A nice new toy in the lab! Can centrifuge thick-walled LCMS glass vials (available from vendor, also with surface treatment).
But Waters TrueView also work pretty well ;)
Time to play with interesting low-volume sample preps!
Hahaha, are u back to covid era?
+
Snapshots from the lab. Xmas-2024 "just for fun" experiments end up in some very useful solutions. Contents of the shiny metal box to be revealed somewhen during the spring -)
Just YEET would be 1000x better