Patrick Aouad: Major Preclinical Models Used to Study Breast Cancer Metastasis - OncoDaily Patrick Aouad: Major Preclinical Models Used to Study Breast Cancer Metastasis / Berthe Hayar, cancer, Cathrin Brisken, Ciara Metcalfe, George Sflomos, Karim

Terrific study! This review will be a super useful tool to people working with preclinical models!

oncodaily.com/voices/patri...

Patrick Aouad: Major Preclinical Models Used to Study Breast Cancer Metastasis - OncoDaily Patrick Aouad: Major Preclinical Models Used to Study Breast Cancer Metastasis / Berthe Hayar, cancer, Cathrin Brisken, Ciara Metcalfe, George Sflomos, Karim

Major Preclinical Models Used to Study Breast Cancer Metastasis - Patrick Aouad

@patrickaouad.bsky.social

oncodaily.com/voices/patri...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews

Preclinical models of breast cancer metastasis: strengths, limitations, and clinical relevance

www.nature.com/articles/s41...

I am really excited to share that our review on preclinical models of breast cancer metastasis is out in npj Breast Cancer! We provide a comprehensive overview of the major preclinical models used to study breast cancer metastasis www.nature.com/articles/s41...

EMT and cancer: what clinicians should know - Nature Reviews Clinical Oncology Despite several decades of research that has revealed roles in the development and progression of many solid tumours, clinical translation of research targeting epithelial–mesenchymal transition (EMT)...

EMT and cancer: what clinicians should know doi.org/10.1038/s415...

ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer - Nature Cancer Liang et al. study the impact of ERα antagonist/degraders against different Esr1 mutations in murine models and find that inhibition of mutant ERα induces lineage plasticity, which is also observed in...

ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer doi.org/10.1038/s430...

The milk-producing structures, called Terminal Ductal Lobular Units (TDLUs), serve as the functional units of the human milk factory. Shown here is a section of #breast tissue stained with carmine alum, highlighting the epithelial structures of the mammary gland. Truly #fascinating! #Science

#Breast picture of the day or should I say painting?
Here's a 3D reconstruction of the human breast rendered into an artistic painting using AI tools! It really does look like something that belongs in a modern gallery. #Science #Art

This week’s 3D reconstruction of the human #breast highlights the #myoepithelial cells- the contractile cells that help squeeze the milk-producing luminal cells to release milk and nourish offspring. Truly fascinating! #Science #Art

Turning my Bluesky profile into a merge of #science 🔬 and #art 🎨: an exhibition featuring the beauty of the #breast through #microscopy. Starting with one of my favorites: 3D reconstruction of the human breast; Staining: Smooth muscle actin; Cells: Myoepithelial cells.

Tumor dormancy: EMT beyond invasion and metastasis More than two-thirds of cancer-related deaths are attributable to metastases. In some tumor types metastasis can occur up to 20 years after diagnosis and successful treatment of the primary tumor, a ...

Our review on Dormancy and EMT received enough views to be a Top Viewed and Cited Article. Read about it here: onlinelibrary.wiley.com/doi/full/10.... #TopViewedArticle @wiley.com

Excited to attend this year’s GRS/C on mammary gland biology! Looking forward to connecting with experts in this inspiring field.