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Posts by Dr Sam Neil

Details | Working at Bristol | University of Bristol

Great job advert: Research Associate in Analytical Chemistry for Cultural Heritage at Bristol

www.bristol.ac.uk/jobs/find/de...

5 days ago 0 0 0 0
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Ancient DNA reveals pervasive directional selection across West Eurasia - Nature Analysis of 15,836 ancient West Eurasian genomes reveals hundreds of instances of directional selection, showing that sustained changes in allele frequency were widespread, rather than being...

Cool paper! Detecting directional selection in ancient DNA over time
www.nature.com/articles/s41...

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Scrutinizing Kinship and Biological Relatedness Through the Lens of Palaeogenomics | Cambridge Archaeological Journal | Cambridge Core Scrutinizing Kinship and Biological Relatedness Through the Lens of Palaeogenomics - Volume 36 Issue 2

I am so happy to share this new paper that I wrote with @cegamorim.bsky.social! We hope that it will help encourage dialogue and collaboration between archaeologists and geneticists trying to understand kinship in the past. www.cambridge.org/core/journal... 🧬🧪

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Its ok, its Oxford....this is totally normal.... #Morrisdancing again

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Dietary inequality marker reveals 10,000 years of gender and cultural disparity in Europe Abstract. Diet is a key to evaluating social and health inequalities over time, as it reflects disparities in access to resources often linked to socioecon

Interesting paper, but do we need to consider data biases? e.g. in northwestern Europe data on biological sex is not available for many burials so far studied with isotopes:

Dietary inequality marker reveals 10,000 years of gender and cultural disparity in Europe.

academic.oup.com/pnasnexus/ar...

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How DNA in dirt is shaking up the study of human origins Nature - Researchers are pulling clues from genetic material in ice age soils and rewriting chapters of human history.

Researchers are pulling clues from genetic material in ice age soils and rewriting chapters of human history

go.nature.com/4dMysup

3 weeks ago 38 11 0 0
NERC Steering Committee - Membership Call - British Geological Survey Supporting information around the call for expressions of interest in joining the NERC Scientific Support and Facilities Steering Committees.

NEIF @isotopesuk.bsky.social are recruiting new members for the NEIF Strategy Group and three Steering Committees (Radiocarbon (Panel A), Life Sciences (Panel B) and Geology & Environment (Panel C)). We are also recruiting for a Chair for Panel A – Radiocarbon. See www.bgs.ac.uk/download/ner...

4 weeks ago 0 2 0 0
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Principal Researcher in Human Evolution:South Kensington

Natural History Museum. Apply for Principal Researcher in Human Evolution jobs.nhm.ac.uk/Job/JobDetai...

1 month ago 20 36 0 3
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Example ChASM Analysis Using Example Data

Want to check your ancient DNA study for chromosomal aneuploidies? RChASM is now available for R, to screen for autosomal and sex chromosomal aneuploidies, such as Down syndrome on data from 0.0014X coverage.

We also wrote a step-by-step tutorial with examples:
jonotuke.github.io/RChASM/artic...

1 month ago 9 7 0 0
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Lasting Lower Rhine–Meuse forager ancestry shaped Bell Beaker expansion - Nature A distinctive population with high hunter-gatherer ancestry persisted 3,000 years later than in most European regions, contributing to later Lower Rhine–Meuse Bell Beaker users.

Proud that after five years of careful analysis and discussion our paper "Lasting Lower Rhine-Meuse forager ancestry shaped Bell Beaker expansion" has now been published.

2 months ago 45 16 4 4
Robust imputation-based method for eye, hair, and skin colour prediction from low-coverage ancient DNA - Scientific Reports The prediction of externally visible traits (eye, hair, and skin colours) from DNA can provide valuable information for contemporary and ancient human populations. The validated HIrisPlex-S method is ...

www.nature.com/articles/s41...

2 months ago 1 0 0 0
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Assessing Ancient DNA Sampling Strategies for Natural Selection Inference in Humans Using Allele Frequency Time Series Data Abstract. The increased availability of genomic data from ancient humans allows estimating the strength of natural selection at a given locus using time se

Interested in using aDNA time-series datasets to estimate selection?

Our study "Assessing Ancient DNA Sampling Strategies for Natural Selection Inference in Humans Using Allele Frequency Time Series Data" is now out in GBE! doi.org/10.1093/gbe/... @genomebiolevol.bsky.social @cegamorim.bsky.social

2 months ago 53 24 2 1
Tracing the Bell Beaker phenomenon through ancient DNA studies Cavazzuti, C., Mittnik, A., Olalde, I., Haak, W. (2025). Tracing the Bell Beaker phenomenon through ancient DNA studies. Budapest : Archaeolingua.

🏺

As well as acting as an insightful review of ancient DNA as it relates to the Bell Beaker Phenomenon in 3rd Millennium BC Europe (particularly the variability and nuances), this also has some great straightforward explanations of analytical methods in aDNA.

cris.unibo.it/handle/11585...

2 months ago 27 7 0 1
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DNA extraction in the lab:
The black blobs in this photo are DNA stuck to magnetic nanoparticles. The DNA is from a site in Britain dated to the earlier Neolithic (the period when farming was beginning).

By putting an external magnet outside the tray we can then separate DNA from a solution.

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Promotional image for the Royal Society of Chemistry's Analytical Research Forum (ARF26) on 15 June 2026 in London, UK, featuring a dynamic blue graphic with electrical effects.

Promotional image for the Royal Society of Chemistry's Analytical Research Forum (ARF26) on 15 June 2026 in London, UK, featuring a dynamic blue graphic with electrical effects.

📢 Announcing the Analytical research forum (ARF26)!
Join us to explore cutting-edge analytical chemistry and its applications across the field.
Find out more: rsc.li/arf2026 #ChemSky

2 months ago 3 3 0 1
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Evidence for the earliest hominin use of wooden handheld tools found at Marathousa 1 (Greece) | PNAS The Middle Pleistocene (MP; ca. 774 to 129 ka) marks a critical period of human evolution, characterized by increasing behavioral complexity and th...

It was such a privilege to get to work on this amazing material from an incredible site and team - now the earliest handheld wooden tools in the archaeological record, taking evidence back to 430,000 years! www.pnas.org/doi/10.1073/...

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Rock art from at least 67,800 years ago in Sulawesi - Nature A hand stencil painted on a cave wall on a small island off the coast of Sulawesi more than 67,800 years ago suggests a very early occupation of Wallacea.

Paintings at least 67 thousand years old in Indonesia
www.nature.com/articles/s41...

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Enjoyed the @bodleian.ox.ac.uk exhibition 'Treasured', featuring many rare manuscripts, including Herculaeum scrolls and the libraries copy of Magna Carta. Worth visiting if you are in the area. Closes 1st February. visit.bodleian.ox.ac.uk/treasured

3 months ago 2 0 0 0
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Well done Sue!!!!!! x

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Walks into the Oxford laboratory under this inscription which reads "Chemistry offers eternal hope" .... that the equipment doesn't break and that the samples produce data

3 months ago 6 1 1 0
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Global patterns of natural selection inferred using ancient DNA Ancient DNA has revolutionized our understanding of human history, and is now yielding important insights into evolution and natural selection. However, studies of selection using ancient DNA have lar...

Interesting pre-print: Global patterns of natural selection inferred using ancient DNA
www.biorxiv.org/content/10.6...

3 months ago 1 0 0 0

“These fossils offer clues about the last common ancestor shared with Neanderthals and Denisovans”

Early hominins from Morocco basal to the Homo sapiens lineage
@nature.com
www.nature.com/articles/s41...

3 months ago 5 7 0 0
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Tracing 2500 years of human betaherpesvirus 6A and 6B diversity through ancient DNA First ancient HHV-6 genomes reveal 2500 years of phylogenetic continuity and provide insights into the endogenization of HHV-6A.

Our paper on the first ancient Human betaherpesvirus 6 A/B (HHV-6) genomes is published in Science Advances! 🥳

In collaboration with @virologyhouldcroft.bsky.social @lucyvandorp.bsky.social @lehtisaag.bsky.social @ktambets.bsky.social & other amazing researchers!

www.science.org/doi/10.1126/...

3 months ago 19 7 2 0
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Genes don’t explain what made humans different Tiny genetic variations between humans, Neanderthals and Denisovans might not be all they were cracked up to be.

This headline is wrong and misleading, and the brief text below it is not much better. Whatever might constitute a full explanation of the differences between sapiens and other hominins, we remain confident that 'genes' will be central to it.

www.nature.com/articles/d41...

4 months ago 58 18 1 2
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Top 10 discoveries about ancient people from DNA in 2024 New resolution is emerging of some events in ancient human populations, and a clearer view of some parts of the genome.

I’m writing up this year’s top discoveries from ancient DNA and it reminded me to circulate a link to last year’s top 10 list. Some amazing stuff there and remarkable how fast this field moves!

www.johnhawks.net/p/top-10-dis...

4 months ago 25 11 0 1
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Ancient DNA insights into diverse pathogens and their hosts Nature Reviews Genetics - Ancient DNA techniques are being applied to study increasingly diverse pathogens of the past. The authors review the latest insights into pathogen–host coevolution,...

Lovely to work with @blevinske.bsky.social, @paleogenomics.bsky.social & Verena Schuenemann on " Ancient DNA insights into diverse pathogens and their hosts"! Read it at rdcu.be/eSVPN

4 months ago 45 17 1 1
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Escaping the laboratory by climbing to the top of one of Bordeaux's bell towers. Constructed in 1440 by the founder of Bordeaux University, Pey Berland.

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Highly selective cannibalism in the Late Pleistocene of Northern Europe reveals Neandertals were targeted prey - Scientific Reports Scientific Reports - Highly selective cannibalism in the Late Pleistocene of Northern Europe reveals Neandertals were targeted prey

Did Neandertals choose their prey when practicing cannibalism?🍖

Check out our new study, just published in Scientific Reports - @natureportfolio.nature.com!

We provide the strongest evidence to date for a highly selective cannibalism at the end of Neandertal lineage, 41-45.000 years ago.

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5 months ago 67 25 4 7
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🦴🧬🦴🧬🦴

Abstract submission is now open for the 1st International Conference on Palaeogenomics!

June 23–26 2026, in Stockholm.

Join researchers from across the field for 4 days and >100 talks (+ poster sessions)!

Submit abstracts here 👉
icp2026.palaeogenomics.org/abstracts/

Deadline: Nov 30th

6 months ago 38 28 1 4
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Amazing presentations at the meeting on Ancient Genomes: perspectives on human biology and medicine at the Royal Society today

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