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Posts by Filippo Del Bene

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IL-22 from enteroendocrine cells promotes early-life gut motility in zebrafish through the microbiota The gut microbiota, immune system, and enteric nervous system interact to regulate adult gut physiology. However, the mechanisms establishing gut physiology during development remain unknown. We repor...

Very happy to share this study from our group and colleagues now out in Science!
We found that in zebrafish, before the immune system is mature, gut epithelial cells perform immune functions by producing the cytokine IL-22 to shape the microbiota to promote early life gut function
#Zebrafish #Gut

2 weeks ago 55 20 2 3
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Two-photon voltage imaging with rhodopsin-based sensors Rhodopsin-based GEVIs were thought to lose voltage sensitivity with two-photon excitation, limiting their utility for deep in vivo imaging. We introduce Jarvis, a bright and photostable GEVI, and demonstrate that, along with pAce and Voltron2, it enables high-contrast two-photon voltage imaging and AP detection at kilohertz rates.
2 months ago 3 3 0 1
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🌟 Meet the Scientific Committee: @filodelbene.bsky.social 🌟

Filippo del Bene is a member of the Scientific Committee of #EZM2026, and we are thrilled to have him join us in Vienna!

Stay tuned as we continue to introduce the outstanding scientists of EZM2026! 🐟🧬

2 months ago 10 4 0 0

A new preprint from our lab is out! πŸ₯³ Congrats to Anyi Zhang and @lucamasin.bsky.social for this great paper titled: Repressed mTORC1 signaling and transient dendritic pruning support axonal regeneration! Grateful for the fruitful collaboration with the @filodelbene.bsky.social and Poulain labs!

2 months ago 4 1 0 1
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Proud to share our new paper uncovering how Lrrn-mediated targeting of retinal ganglion cells assembles circuits for brightness and contrast detection β€” led by my outstanding PhD student Elena Putti and made possible through wonderful collaborations. www.science.org/doi/10.1126/...

2 months ago 12 3 0 1
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Blue-lined octopus Hapalochlaena fasciata males envenomate females to facilitate copulation Chun et al. show that in the blue-lined octopus Hapalochlaena fasciata males envenomate females during copulation, most likely as a defense against being cannibalized.

This article truly refines the concept of a toxic relationship. www.cell.com/current-biol...

1 year ago 2 0 0 0
EZS European Zebrafish Society The European Zebrafish Society was formed as a successor of "EuFishBioMed e.V." to foster zebrafish research, providing a platform for researchers and a framewokr for grant funding for young researche...

Congratulations to Professor Corinne Houart! She's been honoured with the European Zebrafish Society's CNV Award, for oustanding achievements in zebrafish research, as part of her leading research on molecular mechanisms underlying neural development

#AcademicSky

www.ezsociety.org/cnv-awardee-...

1 year ago 7 1 0 0
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πŸš€ Applications Open! Study neural circuits & behavior using cutting-edge techniques in flies, zebrafish & mice!

πŸ“ Champalimaud, Lisbon
πŸ“… June 8-27, 2025
⏳ Apply by March 7
πŸ’‘ Stipends available

πŸ”— Apply now: loom.ly/OMvqMcE

1 year ago 5 5 0 3
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Stainier lab alumni, Save The Date!
30th anniversary celebration of the Stainier lab will take place in Bad Nauheim from Sunday to Wednesday, 6-9 April 2025.
Please block your calendar and spread the word about this scientific and social gathering.
More details to follow!

1 year ago 5 1 0 1
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Basement membranes are crucial for proper olfactory placode shape, position and boundary with the brain, and for olfactory axon development Laminin gamma1-dependent basement membranes are required for multiple aspects of olfactory system development in zebrafish, including the maintenance of placode tissue shape and the growth of the olfa...

doi.org/10.7554/eLif...

1 year ago 9 4 1 0
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7th European Zebrafish Principal Investigators Meeting | PI european zebrafish meeting 2025 Paris | Paris, France The 7th European Zebrafish PI Meeting will be held in Paris, France - April 2 to 5, 2025. Principal investigators in zebrafish research will share their discoveries

πŸ“’ 7th European Zebrafish Principal Investigators Meeting
πŸ“… 2-5 April 2025
🌍 Paris Brain Institute - ICM

#zebrafish @filodelbene @ParisBrainInst
Now extend deadline for abstract submission and registration. January 6th!
www.europeanzebrafishpimeeting.com

1 year ago 7 8 1 1

Thanks!

1 year ago 0 0 0 0
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Myosin 1b regulates intestinal epithelial morphogenesis via interaction with UNC45A Revenu etΒ al. show the function of myosin 1b (Myo1b) in intestinal epithelia. In human cells, MYO1B is part of the UNC45A interactome and contributes to lumenogenesis by modulating spindle orientation inΒ vitro. In zebrafish Myo1b is important for intestinal epithelium folding during the development of the intestinal bulb.

super cool work showing important role for Myo1B, an UNC45A binding partner, in several aspect of intestinal morphogenesis!

www.cell.com/cell-reports...

1 year ago 3 4 1 0