Very excited to have a poster at #BSI25 showing sex-specific #hepatic regulation of #inflammation and #immunity in #liver #steatosis (poster 505)!

@drantonioriva.bsky.social

@britsocimm.bsky.social

#sabv #sexdifferences #liverdisease #masld

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Next steps:
* new immunological associations were highlighted in PBC, warranting further validation studies in bigger cohorts;
* functional studies are needed to investigate these novel biomarkers as suitable immunotherapy targets for PBC treatment.

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Results: increased soluble #HVEM, #interferon #IFN-λ3, #IFN-γ, and #gut barrier permeability significantly differentiated disease stages and UDC response groups.

Soluble Herpes Virus Entry Mediator and Type II/III Interferons Are Upregulated in Primary Biliary Cholangitis Bacterial translocation-induced inflammation and immune dysfunction are recognised factors contributing to the pathogenesis of primary biliary cholangitis (PBC). However, the specific involvement of i...

So happy to announce my first 1st-author publication, on immunological signatures of disease severity and response to #ursodeoxycholate (UDC) in #PrimaryBiliaryCholangitis (#PBC)

doi.org/10.3390/ijms26020605

@drantonioriva.bsky.social @inst-of-liver.bsky.social