Happy Golgi Day

ASCB President Rong Li represented the Society on the global stage this weekend as a plenary speaker at the joint CSCB/APOCB/IFCB International Cell Biology Meeting in Hefei, China.

We’re proud to see ASCB leadership contributing to international collaboration and advancing cell biology worldwide.

Announcement📢- We are delighted to announce that this month's #webinar will be presented by @gthibault.bsky.social titled: 'Enterococcus faecalis redox metabolism activates the unfolded protein response to impair wound healing ’ on Tuesday 28th April 🥳. Register Now: buff.ly/7Nmi0i8

Looking forward to it! We'll cover how E. faecalis hijacks the UPR to shut down wound healing and what that means for chronic infections. See you April 28th.

Linked in post from Sarah Bray The Company of Biologists (known for its 5 journals, Development, Journal of Cell Science, Journal of Experimental Biology, Disease Models and Mechanisms, Biology Open, as well as its charitable activities) is looking to appoint a new CEO. An opportunity to guide the next chapter! More information here:

The Company of Biologists @biologists.bsky.social has a more than 100 year history of supporting science through its journals, meetings, and fellowships. Help lead it into its second century! pls share
www.inspiredselection.com/jobs/jo00000...

We're hiring at NTU SBS, Singapore. Tenure-track faculty position in Biomedical Data Science (computational biology, AI in biology, bioinformatics). Great infrastructure, great place to do science. Please share.

apply.ap1.interfolio.com/119013

I guess the “Sinner is in crisis and needs to reinvent himself“ narrative has now been put to sleep. And the “Sinner is a robot“ one is back? When u think that after Doha, it was the “Alcaraz is now unbeatable“ one. Bless tennis.

Congratulations @claudiobussi.bsky.social!

Research Fellow (Cell Biology) Join Our Team at the School of Biological Sciences, Nanyang Technological University, Singapore The School of Biological Sciences (SBS), part of the College of Science at Nanyang Technological Univers...

We're hiring a Research Fellow (postdoc) in cell biology at NTU Singapore.

The project sits at the intersection of host-pathogen interactions and ER stress biology: CRISPR screens, infection models, lipid peroxidation, wound healing.

Apply or share 👇

ntu.wd3.myworkdayjobs.com/Careers/job/...

AlphaFold hits ‘next level’: the AI tool now includes protein pairing The database of 200 million protein-structure predictions now includes homodimers, adding new biological relevance.

AlphaFold database now includes 1.7 million 'homodimers' - comprising two interacting strands of the same molecule

go.nature.com/4cSmbnT

Congratulations @ronni.bsky.social and @kimingeneva.bsky.social team! Awesome work.

It’s FREE to publish in Journal of Cell Science – there are no page charges, colour charges or hidden fees. And if your institution has a Read & Publish agreement, you can publish immediate OA free of charge.

Find out more: journals.biologists.com/jcs/pages/re...

#forscientists
#notforprofit

Loss of Fsr quorum sensing promotes biofilm formation and worsens outcomes in enterococcal infective endocarditis - Nature Communications Infective endocarditis (IE) is an understudied biofilm-associated infection. Here, analyses of preclinical and clinical data reveal that the Fsr quorum sensing (QS) system of Enterococcus faecalis is ...

What if quorum sensing doesn’t promote biofilms - but restrains it? 🤔

New work from @harisantypas.bsky.social shows that the Fsr QS system in Enterococcus faecalis acts as a brake on biofilm formation and pathogenesis during infective endocarditis (IE).

www.nature.com/articles/s41...

Postdoc job alert in the Crick Institute in London. Are you interested in the actin cytoskeleton? I am looking for a postdoc to examine the cellular, developmental or physiological role of Arp2/3 iso-complex driven actin polymerisation. Multiple aspects available.
crick.ac.uk/WayPostdoc2026

🚨 I am thrilled to share that our lab has been awarded a new grant!

We will soon be recruiting. This project will focus on dissecting host mechanisms as a direct follow-up 👇

If you are interested in cellular stress responses and host-pathogen interactions, stay tuned or reach out for more details!

Cell Bio 2023-An ASCB|EMBO Meeting Network, learn, and collaborate with top cell biologists from around the globe.

Help shape the @ascbiology.bsky.social #CellBio2026 program!

The official call for session proposals is now open! We are looking for innovative ideas for Minisymposia and Special Interest Subgroup meetings for next year’s meeting.

Submit your proposal by February 22

www.ascb.org/cellbio2026-...

So glad to see this paper out! A small but rewarding contribution from our side. It was a fantastic experience collaborating with @kimingeneva.bsky.social, @ronni.bsky.social, and this great global team on such an interesting manuscript.

Enterococcus fans: Check out our latest on E. faecalis EET, advancing our understanding of both the fundamental physiology of this bug and new mechanisms of its virulence. This is the product of a thrilling collaboration with friends in Singapore @gthibault.bsky.social led by @aarontan.bsky.social.

S’pore study finds new way to disarm antibiotic-resistant bacteria, hasten healing of chronic wounds Singapore scientists have found a new way to disarm antibiotic-resistant bacteria and speed up chronic wound healing using catalase. Read more at straitstimes.com. Read more at straitstimes.com.

Excited to see our work covered by The Straits Times ! A great summary by Judith Tan 👇

www.straitstimes.com/singapore/he...

Proud of this international effort led by NTU Singapore, @scelse.bsky.social and the University of Geneva.

Huge props to first author @aarontan.bsky.social and my co-lead @kimingeneva.bsky.social and other authors including @cenkcelik.bsky.social.

#ScienceAdvances #Microbiology #NTUsg

Crucially, we found that we can reverse this paralysis.

By adding antioxidants (like catalase) to the wound, we neutralized the ROS and restarted the healing process. This could be a new blueprint for treating chronic diabetic ulcers when combined with topical antimicrobials.

The evidence is in the movement (or lack thereof). 👇

Left: Uninfected cells closing the wound.
Middle: Infected cells paralyzed by the bacteria.
Right ΔEET): Mutant bacteria that cannot produce the ROS. Note how the wound closes just like the healthy control!

Most bacteria generate ROS inside their cell but E. faecalis generates ROS outside its cell.

Our study shows this process generates hydrogen peroxide at the wound interface. This oxidative stress triggers the unfolded protein response (UPR) in the host skin cells, stopping them from migrating.

Enterococcus faecalis redox metabolism activates the unfolded protein response to impair wound healing E. faecalis EET generates ROS, which induces the UPR in keratinocytes, inhibiting in vitro migration.

We’ve discovered how the superbug E. faecalis prevents chronic wounds from healing.

It’s not a toxin. It’s metabolism.

The bacteria use extracellular electron transport (EET) to electrochemically generate ROS, effectively "freezing" skin cells in place.

doi.org/10.1126/sciadv.aeb5297

We’re hiring!
@jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community!

Details below👇

JCS cover: Marking the end of The Company of Biologists' 100-year anniversary, the final journal cover of 2025 features members of our community, including our academic and guest Editors, our FocalPlane Advisory Board, some of the ‘First Person’ and ‘Cell Scientists to Watch’ scientists featured this year, and our in-house team of administrators and editors at our editorial office in Cambridge.

Issue 24 is complete

Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.

Explore our ToC: journals.biologists.com/jcs/issue/13...

At the helm of JCS – Editors-in-Chief past, present… and future The Editor-in-Chief (EIC) of Journal of Cell Science plays a key role in defining the overall vision of the journal, helping to decide on journal strategy, policy and priorities, and overseeing all co...

What's it like being Editor-in-chief of @jcellsci.bsky.social? doi.org/10.1242/jcs....

JCS logo Cell Bio 2025 logo Our Editors will be attending Cell Bio 2025 Feel free to reach out with any questions you might have about publishing in the journal or other activities from our not-for-profit publisher The Company of Biologists. Picture of Seema Seema Grewal, Executive Editor, seema.grewal@biologists.com Picture of Amelia Amelia Glazier, Reviews Editor, amelia.glazier@biologists.com X: @J_Cell_Sci Bluesky: @jcellsci.bsky.social Instagram: cell_science_stories

Our Editors will be attending #CellBio2025 @ascbiology.bsky.social @embo.org.

Reach out to @seemagrewal.bsky.social and Amelia Glazier to discuss JCS, @focalplane.bsky.social and our other @biologists.bsky.social initiatives.

Graduate

Our application portal is open until 31 January 2026.

Learn more and apply here: www.ntu.edu.sg/science/admi...

#NTU #NTUScience #PhD #GradSchool #Scholarships #STEM #Singapore

NTU College of Science PhD opportunities YouTube video by College of Science NTU

Ready for a transformative research journey? 🚀

Join the vibrant, interdisciplinary PhD programmes at NTU College of Science in Singapore! We offer fully funded scholarships.

Hear from our students and faculty in the video below 👇

youtu.be/JeZHiXu3fgE