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Posts by James D Chalmers

>1400 registered participants from over 40 countries , over 300 questions answered - I love our annual patient conference ❤️❤️

4 weeks ago 1 0 0 0

❤️

1 month ago 2 0 0 0
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ERJ Podcast January 2026: Cannabis and the lung As part of the January issue, the European Respiratory Journal presents the latest in its series of podcasts. Chief Editor James Chalmers interviews editorial board member Janice Leung about the clini

ERJ Podcast: @profjdchalmers.bsky.social interviews editorial board member Janice Leung about the clinical, physiological, imaging and molecular responses to cannabis smoking seen in the CANUCK study https://ow.ly/uSYj50Y5jli

2 months ago 1 1 0 0

Thank you!
Come visit !

2 months ago 1 0 1 0
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ERJ Podcast December 2025: Year in review As part of the December issue, the European Respiratory Journal presents the latest in its series of podcasts. Chief Editor James Chalmers and Deputy Chief Editor Don Sin for their end-of-year roundup

As part of the December issue, the European Respiratory Journal presents the latest in its series of podcasts. @profjdchalmers.bsky.social and Don Sin for their end-of-year roundup of their highlights from the ERJ in 2025. https://on.soundcloud.com/SK1FF0Vk7bDdRb4K4M

3 months ago 2 1 0 0
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The Blue Journal thanks Hayoung Choi, MD, PhD, ATSF, for his contribution to the December issue

Upper-Airway Microbiome, Mucociliary Function, and Clinical Outcomes in Bronchiectasis: Data from the EMBARC-BRIDGE Study
@profjdchalmers.bsky.social

www.atsjournals.org/doi/full/10....

4 months ago 3 1 1 0

Thanks to @profjdchalmers.bsky.social, the landmark research could help 1.3 million people living in the UK with the lung condition. But too many people are waiting years for a diagnosis – and without one, they miss the chance to get access to life-changing treatment.

6 months ago 3 2 1 0
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Professor James Chalmers to join the Radcliffe Department of Medicine We are delighted to announce that Professor James Chalmers has been recruited to the statutory Rhodes Professorship of Experimental Therapeutics and Clinical Pharmacology at the University of Oxford. ...

We are delighted to welcome @profjdchalmers.bsky.social to @rdm.ox.ac.uk as the Rhodes Professor of Experimental Therapeutics and Clinical Pharmacology. James conducts clinical trials and translational research to understand airway disease and develop new therapies. www.rdm.ox.ac.uk/news/profess...

5 months ago 5 2 0 1

Thank you!
Thrilled to take up this new role and to expand our work to improve the lives of people with lung and inflammatory conditions
Science changes lives

5 months ago 8 2 1 0
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Our first speaker at the #CPGonLungHealth is @profjdchalmers.bsky.social . He talks about the world leading work that has been led from his team in Dundee. It’s a condition that doesn’t get the focus it needs and it is incredible what has been achieved in the last 14 years @emmaharpermsp.bsky.social

11 months ago 4 2 0 0
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Broad Immunomodulatory Effects of the Dipeptidyl Peptidase-1 Inhibitor Brensocatib in Bronchiectasis: Data from the Phase 2, Double-Blind, Placebo-controlled WILLOW Trial

A novel treatment for bronchiectasis

@profjdchalmers.bsky.social

www.atsjournals.org/doi/full/10....

11 months ago 4 2 0 0
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Thanks to Emma Johnson, MBBS, MSc, PhD, for contributing to the May issue

Broad Immunomodulatory Effects of the DPP1 Inhibitor Brensocatib in Bronchiectasis: Data from the Phase 2, Double-Blind, Placebo-controlled WILLOW Trial

@profjdchalmers.bsky.social

www.atsjournals.org/doi/10.1164/...

11 months ago 4 2 0 0
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Such an honor and a privilege to share the stage with Rene Wyndham, Susanne Vijverberg, Saglani Sejal, @profjdchalmers.bsky.social, Rory Morty, Sara Cuevas Ocaña and @danielchengyuwu.bsky.social for the early-career delegates session of the 2025 edition of the ERS Lung Science Conference #LSC2025.

1 year ago 6 2 1 0
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European #Bronchiectasis Patient Conference suggestion: bring the checklist to your doctor!!! Am I getting ALL of these recommendations??

1 year ago 6 2 0 0

#Bronchiectasis patient conference was excellent today - even kept me in on a rare sunny day in Scotland - but I got out for a walk afterwards

@profjdchalmers.bsky.social

1 year ago 4 1 0 0
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🔥 🔥 🔥 Hot of the press: Cardiovascular benefits and safety profile of macrolide maintenance therapy in patients with bronchiectasis

buff.ly/CGXv34s

1 year ago 5 4 0 0
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European #Bronchiectasis Pt Conf Sat, March 15th‼️
Amazing experts participating:
✅ Dr. James Chalmers (aka Dr. Bronchiectasis!) from Scotland
✅ Dr. Michal Shteinberg from Israel
✅ Dr. Pamela McShane from the US
…and other international experts!
tinyurl.com/2r5nh6rh

1 year ago 5 2 0 2
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🌟Day 2 at #EBROW25: Breaking New Ground!🌟

Exciting updates on new treatments for #bronchiectasis and #NTM infections from Prof. @profjdchalmers.bsky.social from @dundee.ac.uk & Prof. Charles Daley from @nationaljewish.org

💬 Insightful, interactive, and inspiring!

1 year ago 3 1 0 0

We have so much to learn about the heterogenous disease that is Bronchiectasis! Dr. Thi shared some of the excellent work that is being done around the world, led by @profjdchalmers.bsky.social and colleagues, including therapies to reduce neutrophilic inflammation.

1 year ago 1 1 1 0
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Baseline characteristics of patients in the Chinese Bronchiectasis Registry (BE-China): a multicentre prospective cohort study The clinical characteristics of patients with bronchiectasis in China show differences compared with cohorts in Europe and India. Bronchiectasis is more severe with a higher burden of exacerbations in...

📓We have an #OpenAccess Article reporting on the Baseline characteristics of patients in the Chinese #Bronchiectasis Registry

“The management of patients with bronchiectasis in China urgently needs standardisation and improvement”

www.thelancet.com/journals/lan...

@profjdchalmers.bsky.social

1 year ago 3 2 1 0
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Really enjoyed #RTI2025 & chatting all things 🫁 infection. Many thanks to the organisers for asking me to speak.

Also super proud of Elen Vink for winning the poster prize for her work on the CHARISMA Study. 🏆🥳🙌

@lenagroup4resp.bsky.social
@profjdchalmers.bsky.social
@dbogaert.bsky.social

1 year ago 6 3 0 0
Cardiovascular Benefits and Safety Profile of Macrolide Maintenance Therapy in Patients with Bronchiectasis BackgroundMacrolide maintenance therapy (MMT) has demonstrated notable efficacy in reducing exacerbation in patients with bronchiectasis, which is a major risk factor for cardiovascular events. However, a comprehensive assessment of the cardiovascular benefits and safety profile of MMT in this population is lacking.MethodsThis territory-wide cohort study analyzed patients diagnosed with bronchiectasis in Hong Kong between 2001 and 2018. Patients were classified as MMT receivers or macrolide non-receivers based on the administration of MMT. Propensity score (PS) matching was employed for confounding factors adjustment. The primary outcome of interest was major adverse cardiovascular events (MACE), a composite of cardiovascular death, myocardial infarction and stroke. The safety outcome was the occurrence of ventricular arrhythmias or sudden cardiac death. Cox proportional hazard regression analysis was utilized to compare the incidence of outcomes across the two groups.ResultsA total of 22 895 patients with bronchiectasis were identified. Following 1:2 PS matching, the final cohort consisted of 3137 individuals, with 1123 MMT receivers and 2014 macrolide non-receivers. MMT administration was associated with a significant reduced risk of MACE (16.38 versus 24.11 events per 1000 person years; HR 0.68; 95% CI 0.52–0.90). Importantly, the use of MMT was not associated with elevated risk of ventricular arrhythmias or sudden cardiac death (7.17 versus 7.67 events per 1000 person years; HR 0.93; 95% CI 0.60–1.44).ConclusionsThe administration of MMT in patients with bronchiectasis was associated with a significant reduction in the risk of MACE, without any evidence suggesting an increased risk of severe arrhythmia-related adverse events.

🆕️✨️Large cohort
Administration of Macrolide maintenance therapy in patients with bronchiectasis was associated with a significant reduction in the risk of MACE, without any evidence suggesting an increased risk of severe arrhythmia-related AEs #idsky
publications.ersnet.org/content/erj/...

1 year ago 12 5 0 1
Welcome! You are invited to join a meeting: Extensive Acute and Sustained Changes to Neutrophil Proteomes Post-SARS-CoV-2 Infection. After registering, you will receive a confirmation email about join... During this journal club, Merete Long, PhD, MSc will present the recently published European Respiratory Journal paper which describes their analysis of peripheral blood neutrophils from hospitalized ...

Upcoming journal club "Extensive Acute and Sustained Changes to Neutrophil Proteomes Post-SARS-CoV-2 Infection" on 14 Jan @ 11amET/2pmPT. Register thoracic.zoom.us/meeting/regi... site.thoracic.org/events/exten... @ats-aii.bsky.social @ats-assemblies.bsky.social @profjdchalmers.bsky.social

1 year ago 2 1 0 0
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Sotatercept approved to treat adult patients with pulmonary arterial hypertension (PAH) The Medicines and Healthcare products Regulatory Agency (MHRA) has approved (27 December 2024) the medicine sotatercept (Winrevair) to treat pulmonary arterial hypertension (PAH).

A nice end to the year for PAH patients in UK. www.gov.uk/government/n...

1 year ago 12 2 0 0

Rethinking bronchiectasis as an inflammatory disease - The Lancet Respiratory Medicine

1 year ago 3 2 0 0
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The Precision Medicine Era of Bronchiectasis

Rethinking #bronchiectasis refers to a shift in understanding BE as primarily a chronic inflammatory disease rather than just an infective disorder. This emphasizes the need for early identification of at-risk individuals & the development of anti-inflammatory treatments.
tinyurl.com/yfn7e5at

1 year ago 16 4 1 0
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You are far too kind
Great to see you last week 😀

1 year ago 1 0 1 0

Trial in bronchiectasis has been recently announced ! Watch this space

1 year ago 3 0 0 0
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Heading home after a fantastic #BTSWinter2024 Leaving energised and grateful for friends and the opportunity to talk #mesothelioma in the Plenary Scientific Symposium. Also excited for 2025 under our new BTS President!

1 year ago 14 2 0 0

Thank you so much to @balrcommunity.bsky.social for the early career researcher award. Very grateful for the opportunity to present at #BTSWinter2024 and thankful to everyone in the Dundee respiratory research group for all your support in this project. @profjdchalmers.bsky.social

1 year ago 8 2 0 0