Extracellular vesicles derived from senescent hepatocytes drive pan-cancer metastasis in aging - Nature Aging Investigating how aging predisposes individuals to a higher metastatic risk, the authors identify that extracellular vesicles secreted by senescent hepatocytes carry miRNAs that enhance metastatic pot...

www.nature.com/articles/s43...

Targeting tumor dormancy: the next frontier in gastrointestinal stromal tumor therapy Gastrointestinal stromal tumors (GISTs), the most common mesenchymal neoplasms of the digestive tract, are primarily driven by mutations in KIT/PDGFRA…

www.sciencedirect.com/science/arti...

Adjuvant Chemotherapy Outcomes in Older Adults With Nonmetastatic Triple-Negative Breast Cancer This cohort study assessess whether adjuvant chemotherapy is associated with breast cancer mortality among women 70 years or older with nonmetastatic triple-negative breast cancer.

jamanetwork.com/journals/jam...

Had a great Northern NYC Heme club intro @newyorkbloodcenter.bsky.social ! Great talks across the spectrum of Heme cancer biology, Clonal hematopoiesis, blood cell development from new colleagues across NY :) @sinaiimmuno.bsky.social @cdi-einstein.bsky.social @einsteincellbio.bsky.social

🔥 19 scientists. 🌍 One global stage.

Celebrating 19 @niaidnews.bsky.social awardees at our B Cells & Plasma Cells / B & T Cell Collaboration meeting!

The future of immunology is here 👏

#KSBCells26 #KSBTCells26 @kimljacobson.bsky.social @deeptabhattacha.bsky.social @zivshulman.bsky.social

Don't miss it!

Huge congratulations to first author Mohd Nauman and all the co-authors and collaborators who made this story possible!

@cdi-einstein.bsky.social
@einsteinmededu.bsky.social
@monteeinsteinpath.bsky.social

Super excited to visit NYU Cancer Center tomorrow, and catch up with friends and colleagues sharing our most recent work @cdi-einstein.bsky.social. See you!

www.nature.com/articles/s41...

New work from CDI Member Hayley McDaid. Congrats! www.biorxiv.org/content/10.6...

Good morning! this week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation www.science.org/doi/10.1126/...

Congratulations Nauman and @dentenberg.bsky.social for this important study!

Cancer's new nemesis: mRNA-based jab zaps tumours, enters human trials Cancer now ‘fightable’ with a jab?  mRNA-based cancer vaccine human trials on

In the battle against cancer, a new hero has entered the chat.

One innovation came from UMass researchers who created a tiny particle–based cancer vaccine that stopped tumors from growing in lab tests. gulfnews.com/world/cancer...

Why cancer can come back years later — and how to stop it Researchers are targeting dormant tumour cells that might explain why some cancers reappear long after successful treatment.

Important to see the acknowledgement of cancer dormancy & that top journals continue to highlight & publish on this topic. This problem is now studied in major Institutions worldwide. Congrats to all who work in this space! It is making & will make a difference! www.nature.com/articles/d41...

Why cancer can come back years later — and how to stop it Researchers are targeting dormant tumour cells that might explain why some cancers reappear long after successful treatment.

www.nature.com/articles/d41...

Single-cell resolution of an open chromatin signature in persister tumor cells Cancer can recur when a subset of tumor cells, termed persister cells, survive therapy and re-enter the cell cycle. Through single-nucleus multi-omic …

www.sciencedirect.com/science/arti...

We wrapped the @cdi-einstein.bsky.social Retreat with four impressive projects from our workshop by Unai Heras Manterola, Lindsay Lafave, Maria Sosa, and Kamini Singh—covered dormancy & bioengineering, neoantigens, transcriptional heterogeneity & lung cancer. Wow! Thanks to all who participated!

Now Wenjun Guo @cdi-einstein.bsky.social presenting his work on MLL3 loss and metastasis initiation.

Today we had a phenomenal first day of our @cdi-einstein.bsky.social retreat. Great talks by @soledadsosalab.bsky.social Anna Skwarska and John McAuliffe.

Exciting to wrap up the presentations at our CDI retreat with two phenomenal talks by @cdi-einstein.bsky.social latest recruits who will start in 2026 @swagatag.bsky.social from @mit.edu and @samhegde.bsky.social from @mountsinainyc.bsky.social welcome to @einsteinmededu.bsky.social

The @cdi-einstein.bsky.social retreat is tomorrow! Featuring 1.5 days of exciting science with keynote by Dr. Lewis Chodosh (UPenn) and talks from our faculty and students. Thanks to MECCC, SWCRF, and Pershing Square Philanthropies for their support!

Getting ready to start our @cdi-einstein.bsky.social Retreat!

Now the Keynote Lecture at our @cdi-einstein.bsky.social retreat delivered by @amulyasreekumar.bsky.social from the Chodosh team at University of Pennsylvania - great work!

Exciting science presented by @wenjunguolab.bsky.social !

A day of exceptional science delivered by CDI Members. Thanks for joining the Retreat!

Anti-progestin therapy targets hallmarks of breast cancer risk - Nature Results of an early-phase breast cancer prevention trial demonstrate the potential for breast cancer prevention in premenopausal women with anti-progestin therapy by inducing epithelial–stromal remode...

www.nature.com/articles/s41...

The CDI retreat is only one day away! 1.5 days of exciting science including our keynote speaker Dr. Lewis Chodosh @upenn.edu and talks by our members and new recruits (TBA soon)! Thanks to MECCC, Samuel Waxman Cancer Research Foundation & Pershing Square Philanthropies for their support!

The MRS is excited to announce the awardees for the 2026 MRS Awards. Congratulations to all of the awardees! 🏆 Paget-Ewing Award (Honoring scientific excellence and substantial contributions to… | M... The MRS is excited to announce the awardees for the 2026 MRS Awards. Congratulations to all of the awardees! 🏆 Paget-Ewing Award (Honoring scientific excellence and substantial contributions to the ...

CDI Director Dr. Aguirre-Ghiso receives highest honor from the metastasis research society. Importantly, this & the Fidler Innovation Award to Dr. Cyrus Ghajar at @fredhutchprotons.bsky.social recognize the discoveries and research on cancer dormancy.
www.linkedin.com/posts/metast...

FAK Inhibition Demonstrates Dual Effects of Tumor
Suppression and Dormancy Induction Through
Region-Specic COUP-TF1 Regulation
assets-eu.researchsquare.com/files/rs-761...

Congratulations to CDI Member Eugen Dhimolea and collaborators at CDI and elsewhere for their recent publication revealing vulnerabilities of quiescent triple negative breast cancer cells persisting after chempotherapy : www.mdpi.com/2073-4409/14...