Diffusion MRI (dMRI) is a powerful tool to study white matter maturation. In our new preprint, we process and distribute a new resource of >24,000 ABCD dMRI scans using open source tools! We then evaluate how methods shape inferences about development.

🔗 www.biorxiv.org/content/10.6...

Thalamocortical constraints on areal connectivity in the developing human brain www.biorxiv.org/content/10.64898/2026.03...

How may rare vs. common genetic variation separately influence how our brains – and their complex folding patterns – take shape? 🧬 🧠
Check out our new preprint (and final work from my PhD!) out now! ( + thread below) www.biorxiv.org/content/10.6...

Exploring the Role of the Rich Club in Network Control of Neurocognitive States Using a network control theoretical framework, we found that the brain's rich club does not optimally control dynamics of the brain. Instead, size-matched sets of random peripheral regions had a sign...

🚨 New paper from @apodschun.bsky.social (with Sebastian Markett, Urs Braun, and myself)

Exploring the Role of the Rich Club in Network Control of Neurocognitive States

onlinelibrary.wiley.com/doi/10.1002/...

Brain Growth Patterns Predict 2-Year Neurodevelopment bioengineer.org/brain-growth...
Growth of fetal brain with long-term neurodevelopmental validation provides insights into in utero brain maturation and their predictive relationship with postnatal neurological function. doi.org/10.1038/s414...

The Extremely Brilliant Brain: An Isotropic Microscale Human Brain Dataset www.biorxiv.org/content/10.64898/2026.01...

Dissecting gene regulatory networks governing human cortical cell fate - Nature Systematic screening of transcription factors reveals conserved mechanisms governing cortical radial glia lineage progression across primates and provides a framework for functional dissecti...

1/ Our new study, led by Jingwen Ding, examines the role of transcription factors during human neurogenesis to identify gene regulatory networks influencing cell fate, maturation, and subtype specification
www.nature.com/articles/s41...

Preprint on PANDORA by Aslan Abivardi:

A massive archive of UK Biobank brain imaging from 82K subjects. For each of 98 sub-modalities (e.g., FA from dMRI), the images are collated into a convenient subjectsXvoxels HDF5 file.

pages.fmrib.ox.ac.uk/pandora/web/

www.medrxiv.org/content/10.6...

Incredible resource of ~1M single-cell transcriptomes, NeuRoDev, that captures temporal and cellular variation across human brain development. Congrats to Asia Zonca and Erik Bot from the Davila-Velderrain group at @humantechnopole.bsky.social for leading this work!

www.biorxiv.org/content/10.6...

🧠🪰 The adult Drosophila brain connectome now gives us a complete wiring diagram of ~140k neurons. But a wiring diagram alone isn’t understanding.

How is this massive network organized?

Our paper tackles that question by mapping community structure across the entire fly brain. 1/

Connectomics is Method of the Year 2025!!
@natmethods.nature.com
just released the news nature.com/articles/s41... In my perspective piece, I afford some predictions into the future and compare how we are doing vs. genomics www.nature.com/articles/s41...

A spatial transcriptomic atlas of autism-associated genes identifies convergence in the developing human thalamus www.biorxiv.org/content/10.1101/2025.11....

🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f

Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience

➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?

Check out what we found!
🧵1/n

Multimodal imaging of human fetal brain development at the mesoscopic scale using 11.7 T ex vivo MRI www.biorxiv.org/content/10.1101/2025.09....

🔥ATTENTION!🔥

Registration for the 2026 Noosa Brain Workshop is now open!

Join us for some amazing science, sun, and surf in one of Australia's most beautiful beach towns.

Details:
tinyurl.com/arbc5pp6

Check out or incredible list of confirmed speakers. More to come...

Expanding canonical cortical cell type markers in the era of single-cell transcriptomics www.biorxiv.org/content/10.1101/2025.08....

Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...

Spatial transcriptomics reveals human cortical layer and area specification - Nature Multiplexed error-robust fluorescence in situ hybridization (MERFISH) together with deep-learning-based nucleus segmentation enabled the construction of a highly detailed and informative spatially res...

Spatial transcriptomics reveals human cortical layer and area specification www.nature.com/articles/s41... - early emergence of layers; graded differentiation along A/P axis, w/ early, sharp V1/V2 boundary

Research Officer Job in Parkville, Melbourne VIC - SEEK We are seeking a Postdoctoral Research Officer to drive international neuroimaging research into childhood NF1 brain development.

JOB ALERT! We're seeking a postdoctoral scientist to join Developmental Imaging at @mcri.bsky.social in Melbourne.

Role will involve working with international partners on a new project charting brain growth in children with NF-1

Please reach out for more information

www.seek.com.au/job/86090834

Research Officer Job in Parkville, Melbourne VIC - SEEK We are seeking a Postdoctoral Research Officer to drive international neuroimaging research into childhood NF1 brain development.

JOB ALERT! We're seeking a postdoctoral scientist to join Developmental Imaging at @mcri.bsky.social in Melbourne.

Role will involve working with international partners on a new project charting brain growth in children with NF-1

Please reach out for more information

www.seek.com.au/job/86090834

Big fan of acronyms

1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...

Human thalamocortical structural connectivity develops in line with a hierarchical axis of cortical plasticity - Nature Neuroscience Sydnor et al. developed a new tractography atlas of thalamocortical structural connections and applied it to three youth samples. They uncovered coordinated development between thalamic connectivity a...

Human thalamocortical connectivity matures along the cortex’s sensorimotor–association axis

www.nature.com/articles/s41...

A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution - Nature A stereotaxic atlas of the whole mouse brain, based on a Nissl-stained cytoarchitecture dataset with isotropic 1-μm resolution, achieved through continuous micro-optical sectioning tomography, promise...

A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution
www.nature.com/articles/s41...

Competing Programs Shape Cortical Sensorimotor-Association Axis Development The neocortex is organized along a dominant sensorimotor-to-association (S-A) axis, anchored by modality-specific primary sensorimotor areas at one end and transmodal association areas that form distr...

Thrilled to present MIND!

A model for how the sensorimotor–association axis of the neocortex develops.

Huge thanks to the incredible multidisciplinary team who made this happen.

www.biorxiv.org/content/10.1...

Addressing artifactual bias in large, automated MRI analyses of brain development - Nature Neuroscience As large-scale neurodevelopmental MRI studies gain prominence, the authors identify tradeoffs between sample size and quality control that can dramatically affect results, and they evaluate a range of...

Addressing artifactual bias in large, automated MRI analyses of brain development | Nature Neuroscience
www.nature.com/articles/s41...

On Friday/Saturday I have a poster (1205) on our work using generative network models, where I explore how heterochronous spatial gradients constrain brain connectivty 🧠⌛🏳️‍🌈 Also Saturday (11:30am; Great Hall) I have a talk on this work, so make sure you have recovered from club night in time for it!

For those at OHBM, check out my posters and talk! Today and tomorrow I (and maybe @garedaba.bsky.social) will be presenting my poster (1012) on our work linking fetal gene expression to neonatal connectome organisation 🧬🧠👶🌐 1/2 #OHBM #OHBM2025 (preprint here www.biorxiv.org/content/10.1... )

Accurate spatial localization of Allen Human Brain Atlas gene expression data for human neuroimaging www.biorxiv.org/content/10.1101/2025.06....

Macroscale Connectivity in the Octopus brain www.biorxiv.org/content/10.1101/2025.05....