NAD+ precursor supplementation in human ageing: clinical evidence and challenges - Nature Metabolism This Review summarizes existing data, as well as crucial knowledge gaps, emerging from clinical trials involving NAD+ precursor supplementation in humans.

#Throwback 🧪

REVIEW | NAD+ precursor supplementation in human ageing: clinical evidence and challenges

@rhhoutkooper.bsky.social, K Vinten et al.

📣 Metabolic #cardiomyopathies: untangling clinical heterogeneity with human #StemCell derived models

By A. Passadouro, @rhhoutkooper.bsky.social, S. Mosegaard & colleagues at University of Amsterdam

➡️ doi.org/10.1038/s443...

Good luck Alex, and see you soon in Amsterdam

Choose Europe for Science: ERC welcomes new budget for 'super grants' The Scientific Council of the European Research Council welcomes the offer of substantial additional budget from the European Commission for the development of a new ERC funding instrument offering la...

erc.europa.eu/news-events/...

EU augments opportunities for scientists around the world to launch or re-launch their careers in Europe.

In line with our expectations, we found marked changes in markers of mitochondrial function and in energy status of hearts from people with Barth syndrome. Confirming this in this unique tissue sample is a major step forward and hopefully one of the building blocks on our path to therapy.

First of all, we are super grateful to the affected individuals and their families for the courageous decision to share their heart for research purposes. And to the Barth Syndrome Foundation for orchestrating the biobank at University of Florida, as well as their financial support! 🙏🏼

We publish our multi-omics analyses of cardiac samples obtained from people with Barth syndrome, in comparison to hearts from people without heart failure.

www.biorxiv.org/content/10.1...

Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics - Nature Metabolism Pathway analysis, originally developed for gene expression data, has been adapted for metabolomics. However, owing to the unique characteristics and constraints of metabolites compared with genes, pat...

www.nature.com/articles/s42...

Metabolites are not genes. repeat, please!

I am excited to speak at #ARDD2025, the world’s largest conference on aging research and drug discovery! Join me in Copenhagen, August 25-29, 2025 to connect with top scientists, biotech pioneers, pharma leaders, and investors driving innovation in longevity science.

Register: agingpharma.org

Save the date! DTMC 2025 is promising to be super exciting! Watch this space for updates, or sign up for the newsletter!

We likely need to curate a geroscience pack - I would also be interested!
Tagging the scientists in that space that I know are here and can think of:
@ctmurphy1.bsky.social
@mattyousefzadeh.bsky.social
@jennifergarrison.bsky.social @trowbridgelab.bsky.social