“the team showed that interrupting a key step in meiosis, the process that produces sex cells, can temporarily halt sperm production without causing lasting harm.”
#Sperm #Fertility #Contraception 🧪
www.sciencedaily.com/releases/202...
Posts by Pépin Lab
Can gene therapy replace surgery? 🐈🔬 Join Philippe Godin & Savannah Speckhart for our 2nd Journal Club! We’re discussing AMH delivery for long-term sterilization in domestic cats. A game-changer for vet med!
Register: ssr.org/events/upcoming-events/t...
Join us March 6 @ 4 PM for the Roger V. Short Lecture w/ Dr/ David Pépin. We’re discussing AMH breakthroughs in contraception, oncofertility, and feline health.
Register: ssr.org/events/upcoming-events/r...
CRS Co-Director Dr. Francesca Duncan, and CRS faculty members Dr. Kara Goldman and Dr. Monica Laronda were featured in this New York Times article! Check it out!
www.nytimes.com/2025/12/27/h...
Well done Josephine! Talk about multitalented…
The SRB, SRF and SSR have announced that A/Prof. David Pépin of the Massachusetts General Hospital and Harvard Medical School is the 2025 Recipient of the RV Short Medal and Lecture.
A/Prof. Pépin has made significant contributions to understanding the role of AMH in fertility.
We're looking for a Postdoctoral Fellow in Machine Learning & Women’s Health in partnership with MIT’s Female Medicine through Machine Learning (FMML fmml.mit.edu ) to build multi-modal ML models related to ovarian aging and its impact on overall health using large, real-world datasets.
This is incredible.
Director of the Nat'l Institute of Child Health and Human Development (NICHD) was summarily dismissed yesterday. So here's your reminder that birth defects kill twice as many American kids as cancer. But there is no St. Jude's for birth defects. Only the NICHD.
www.nature.com/articles/d41...
So proud of our brilliant PhD student Alana Mermin-Bunnell, and thankful for all her work to implement a machine learning follicle counting pipeline.
I’m excited to share the latest work from our lab, led by a group of three amazing scientists: Junbing Zhang, Yousuf Ali and Harrison Chong, who describe @nature the discovery of a ROS sensor, VPS35, which links cytosolic H2O2 levels to regulation of mitochondrial translation and
Universities aren't doing enough to come to each others' defense, and industry isn't standing up for academia, says @hollylynchez.bsky.social:
A great summary on the war against academia and the root of the rising anti-intellectualism open.substack.com/pub/paulwald...
Nothing will kill more children than the ongoing decimation of CDC, NIH, and USAID work to lift vaccine uptake in the US and world.
Child survival rose 75% in the last 50 years. Vaccines account for 40% of that. Measles vax alone was 60% of the benefit. www.thelancet.com/journals/lan...
The House of Representatives just passed a CR that includes devastating cuts to the Congressionally Directed Medical Research Program (CDMRP) – 57% cut.
It is absolutely critical that we reach out to our Senators now and urge them NOT to include these cuts.
Call them!
This is a useful resource if you’re trying to keep track of NIH study section meetings, a google doc kept up to date by Dr Barber. docs.google.com/spreadsheets...
You know it’s bad when the scientists go outside.
For those in the Boston area, the stand up for science demonstration will be at the capitol this Friday 3/7 12-4. i0.wp.com/standupforsc...
I am not going to call this a Bluetorial, because I do not want to sully that term (which, at least I, find joyful).
Let’s call it a Orwellial.
Senior investigators are now on the chopping block. We could all suffer the same fate if we can’t unite to stop the willful dismantling of scientific research. www.science.org/content/arti...
If you are worried about science there IS something that you can do! Join us next Friday in DC to make your voice heard. Come and stand up for science! Show that science is for everyone. I’ll be there and I can’t wait to see you there too!
@standupforscience.bsky.social
Medical research funding is usually both public (NIH) and private (pharma), i.e. the TV drug ads
Preterm birth & preeclampsia research is almost entirely non-industry
Most pharmaceutical companies avoid pregnant patients like the plague.
So freezing NIH essentially freezes our field
#MedSky
Get ready to #standupforscience in 2.5 weeks!
#BREAKING - 22 states sue to block Trump administration cuts to NIH research payments
#BREAKING - NIH plans to slash support for indirect research costs, sending shockwaves through science
It’s definitely over for those of us doing research at hospitals.
The Ovarian Cancer Research Syndicate schedule is out from the @pennmedicine.bsky.social Ovarian Cancer Research Center. Great line up!
Congrats to Dr Godin who did a great job presenting our work on cat contraception at #Fertility2025. We’ve shown that we can treat kittens with AMH gene therapy before puberty and they will be contracepted at maturity with no adverse effects on hormones! Finally, a non-surgical alternative for pets.
You should leave an elf on the shelf there!
Next: we hope to develop therapies to neutralize FSTL3 to potentiate ICB and see if FSTL3 can be a clinically useful blood biomarker in patients with ovarian cancer. We thank the patients, collaborators at #INSERM and at the Whitehead and funding from MGH, MIT-Bridge, and the DoD.