2/2 Using PhagoCyt, we reveal how Salmonella reshapes its phagosomal niche, show organelle recruitment to phagosomes, and discover new putative bacterial effectors!
Feedback is very welcome — more exciting updates soon! 🧬🧫 #Phagocytosis #Proteomics #InfectionBiology

Flow cytometry-based isolation combined with ultra-sensitive proteomics of Salmonella-containing phagosomes reveals novel insights into host-pathogen interactions Macrophages engulf pathogens into dynamic phagosomes, which many bacteria manipulate for survival. However, isolating pure pathogen-containing phagosomes remains challenging. Here, we developed a nove...

1/2 Thrilled to share my first preprint from my postdoc in #TrostLab, NCL
🚀We developed PhagoCyt, a flow cytometry-based method to isolate Salmonella-containing phagosomes, coupled with ultra-sensitive proteomics to map host-pathogen interactions in depth.
Check it out here 👉 doi.org/10.1101/2025...

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