Abstract submissions are open for #Tau2026. This global conference from @alzassociation.bsky.social, The Rainwater Charitable Foundation and CurePSP brings together researchers and perspectives to move tau research forward. Submit your abstract by Feb. 18: alz.org/Tau
"Join @alzassociation.bsky.social, The Rainwater Charitable Foundation and C #Tau2026, May 14-15, 2026, in Washington, D.C., and online! Be part of the c leading experts work to move tau research forward. Register now: alz.org/Tau"
Microglia show strong activation in PS19 P301S MAPT mice. Deleting TIA1 in the microglia prevents this activation! Gorgeous reconstruction of the microglia provided by Zeta Papadimitriou and Joana SIlva (U. Minho, Portugal).
New Wolozin Lab preprint on BioRxiv:
Webber, C. J., et al TIA1 Mediates Divergent Inflammatory Responses to Tauopathy in Microglia and Macrophages, BIORXIV/2024/622325 (2024).
Cool story using CX3CR1 driven TIA1 cKO mice crossed to P301S MAPT mice.
Flow chart for using SQSTM1::TurboID
We recently published a new approach to characterizing protein aggregates using SQSTM1 (p62) TurboID!
Rondón Ortiz AN, et al, Proximity labeling reveals dynamic changes in the SQSTM1 protein network. JBC. (2024) doi.org/10.1016/j.jbc.2024.107621
Hi everyone, after a long hiatus, the lab has once again determined how to post, using BlueSky instead of X!!! (Avoiding support for Musk - a great entrepreneur/Engineer but irritating person.) So, the next couple of tweets will convey updates. I recommend BlueSky!!