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Posts by Elise Lepeltier

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Registration is open for the 11th SFNano Annual Meeting 2025 that will take place on November 24th – 26th in Lyon, France!
Early bird registration fee until October 15th.
Abstract submission deadline is on September 15th.
For more information and registration:
sfnano2025.univ-lyon1.fr/fr

9 months ago 4 2 0 0
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Today it is the MINT Day! A good occasion to share science and good moments together. We are really happy to welcome @aklymchenko.bsky.social to open this beautiful day! Thank you very much again for coming ☺️.

10 months ago 4 2 0 0
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Congratulations to Dr. Cécile Doualle for your excellent PhD defense! We are all proud of you!
Congratulations also to your supervisors Dr. Franck Letournel and Dr. Julien Gouju.

10 months ago 1 1 0 0
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Calling all researchers working on nanomedicines for crossing biological barriers 📢 Submit your latest research to this exciting themed collection in Nanoscale by 16 May 2025 🗓 Find out more about the collection and how to submit 🔗 blogs.rsc.org/nr/2024/10/2...

1 year ago 5 2 0 0
Self-assemblies of cell-penetrating peptides and ferrocifens: design and biological evaluation of an innovative platform for lung cancer treatment Chemotherapy currently used for lung cancer treatment often consists in a combination of drugs, with a moderate efficacy and severe side effects. A major drawback of the classical inorganic drugs used...

A new article from @labmint.bsky.social by notably Dr. Abdallah Ladaycia and Dr. Léna Guyon, supervised by @elepeltier.bsky.social published in @nanoscale-journals.rsc.org:
pubs.rsc.org/en/content/a...

1 year ago 2 1 0 0

New article from @labmint.bsky.social by notably Dr. Claire Gazaille and Dr. Guillaume Bastiat:
"Focus on the importance of the process parameters: Temperature cycles and “shock” water addition during the phase inversion process for the formulation of lipid nanoparticles"

1 year ago 1 1 0 0
Journée LNP SFNano | Framaforms.org

Nous sommes heureux de vous convier à une journée d’échanges autour des « Formulations Lipidiques pour la Libération d’ARN » le jeudi 3 Avril 2025, à la Faculté de Pharmacie Paris 5.
Le nombre de places est limité. Inscriptions obligatoires en ligne :
framaforms.org/journee-lnp-...

1 year ago 1 1 0 0
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Congratulations @ZarikianLaura for your great talk at the @SFNano_official annual meeting in @Toulouse : you can be proud of you!

1 year ago 2 0 0 0
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Wonderful talk @H_H_Genedy from @LabMint at the @CRSBeNeLuxFr congress to present our PRC @AgenceRecherche NEMESIS project: congratulations ☺️.

1 year ago 1 0 0 0
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Excellent talk @H_H_Genedy from @LabMint at #EMJMD_NANOMED Workshop: congratulations !!!

1 year ago 2 0 0 0
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Congratulations @MelinaGuerin29 from @LabMint for your excellent presentation at #EMJMD_Nanomed workshop!!!

1 year ago 0 0 0 0
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Congratulations Bilel Laoulaou from @RMeS_UMR1229 and from @LabMint for your brilliant talk !! And thank you @AgenceRecherche for the support ! And last but not least: thank you Johann Clouet 😁

1 year ago 0 0 0 0

A beautiful review with @RMeS_UMR1229 in @ADDReditors by notably @H_H_Genedy, Paul Humbert, @Cath_LeVisage, @JeromeGuicheux, @CPassirani and Johann Clouet: first article from our @AgenceRecherche PRC projet “Nemesis”: congratulations to all of you 🥂.

sciencedirect.com/science/articl…

2 years ago 0 0 0 0
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It was a great @SFNano_official annual meeting in Montpellier, @LabMint was more than well represented: a big thanks to each of you @MelinaGuerin29, @H_H_Genedy, Bilel Laoulaou and Laura Zarikian 😊🎉

2 years ago 0 0 0 0
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Congratulations @H_H_Genedy for your great talk at @SFNano_official annual meeting in Montpellier: well done 👍🏻

2 years ago 1 0 0 0
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Tellement honorée, merci infiniment @InstUnivFr
@LabMint @UA_Recherche @UnivAngers @FacSante_Angers

2 years ago 1 0 0 0
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Nous sommes à la recherche d’un étudiant pour un stage de Master 2 au @LabMint dont le sujet porte sur la formulation de nanocapsules lipidiques chargées en ARNm pour le traitement de maladies génétiques de l’œil
Si intéressé, envoyez-moi votre CV: elise.lepeltier@univ-angers.fr

2 years ago 0 0 0 0
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What a wonderful gift for a chemist 🤩: thank you very much again @Milad_Bar @MelinaGuerin29 @H_H_Genedy @CPassirani @Cooltrail @lautram_no49460 @Lemaire_LabMint @f_franconi, Bilel, Gloria and Laura, I am
really lucky 😍!

2 years ago 0 0 0 0

Merci beaucoup @seb_faure 😊

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2 years ago 0 0 0 0
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Your first poster at @icat_sfr seminar @MelinaGuerin29 and not the last one 😊: congratulations 🎉

2 years ago 1 0 0 0
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Oooo I still don’t believe in it 😭. Sometimes life can be very difficult, but life can also be really beautiful. Thank you very much @InstUnivFr ! It is such an honor. And of course, thank you all my team of students 😊.
@UnivAngers @UA_Recherche @InsermGrdOuest @CNRS

x.com/LabMint/status…

2 years ago 1 0 0 0

Today, I was the reviewer of @dasilvalex’s PhD thesis at @umr8612 : congratulations again Alexandre and thank you Sinda Lepêtre and Patrick Couvreur for your invitation 😊.

3 years ago 0 0 0 0
Physicochemical Characterization of Ferrocifen Lipid Nanocapsules: Customized Drug Delivery Systems Guided by the Molecular Structure Ferrocifens, lipophilic organometallic complexes, comprise a biologically active redox motif [ferrocenyl-ene-p-phenol] which confers very interesting cytotoxic properties to this family. However, because of their highly lipophilic nature, a formulation stage is required before being administered in vivo. In recent decades, ferrocifen lipid nanocapsules (LNCs) have been successfully formulated and have demonstrated anticancer activity on multidrug-resistant cancers in several mice and rat models (glioblastoma, breast cancer, and metastatic melanoma). A recent family of ferrocifens (succinimidoalkyl-ferrociphenols, including P722) appears to be most efficacious on several resistant cancer cell lines, with IC50 values in the nanomolar range together with promising in vivo results on murine ovarian cancer models. As LNCs are composed of an oily core (caprylic/capric triglycerides), modulation of the succinimido-ferrociphenol lipophilicity could be a valuable approach toward improving the drug loading in LNCs. As the drug loading of the diphenol P722 in LNCs was low, it was structurally modified to increase its lipophilicity and thereby the payload in LNCs. Chemical modification led to a series of five succinimido-ferrocifens. Results confirmed that these slight structural modifications led to increased drug loading in LNCs for all ferrocifens, with no reduction of their cytotoxicity on the SKOV3 ovarian cancer cell line. Interestingly, encapsulation of two of the ferrocifens, diester P769 and monophenolic ester (E)-P998, led to the formation of a gel. This was unprecedented behavior, a phenomenon that could be rationalized in terms of the positioning of ferrocifens in LNCs as shown by the decrease of interfacial tension measurements at the water/oil interface. Moreover, these results highlighted the importance of obtaining a gel of this particular motif, in which the acetylated phenolic ring and the succinimidoalkyl moieties are mutually cis relative to the central double bond. Promising perspectives to use these ferrocifen-loaded LNCs to treat glioblastoma could be readily envisaged by local application of the gel in the cavity after tumor resection.

So happy to share with you our last article published in @ACS_Langmuir from @IdlasP’s PhD Thesis founded by @AgenceRecherche with @Feroscan_PSL 🤩!! Thanks all the co-authors, notably @GBastiat, @CPassirani, Prof. Jaouen and Prof. Vessières!

pubs.acs.org/doi/10.1021/ac…

3 years ago 0 0 0 0

Please RT would be appreciated, thank you 😊

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3 years ago 0 0 0 0

Tellement fière de toi @IdlasP !! 🦾

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3 years ago 0 0 0 0

Thank you @icat_sfr ☺️

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3 years ago 0 0 0 0

Congratulations @IdlasP and @A_Ladaycia for this work 😊🎉

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3 years ago 0 0 0 0

A new article between @LabMint and @RMeS_UMR1229, from the PhD work of @BrianLemoal with notably as authors @JeromeGuicheux, @Cath_LeVisage, @CPassirani: congratulations 😊

authors.elsevier.com/a/1fMQo1M49kXF…

3 years ago 0 0 0 0

Nemesis project accepted by @AgenceRecherche led by @RMeS_UMR1229 🍾🍾🍾: a huge recognition of our collaboration 🤩 @LabMint

3 years ago 0 0 0 0