Review @cp-cellstemcell.bsky.social @viktri08.bsky.social @embl.org @pflenne.bsky.social
Physics-based approaches illuminate organoid development and homeostasis by integrating mechanical, chemical, and informational processes
www.cell.com/developmenta...

Vanessa Weichselberger (from @viktri08.bsky.social lab) uses mouse organoids to investigate how "Physical confinement shapes the morphogenetic landscape in gastruloids, generating distinct emergent patterns".

¿Qué nos falta para entender la célula viva? - El·lipse En el tercer episodio de Science With A View, Alfonso Martínez-Arias (MELIS-UPF) y Vikas Trivedi (EMBL Barcelona) se adentran en un debate profundo sobre el conocimiento actual de las células vivas.

🎙️ @amartinezarias.bsky.social (@upf.edu) y @viktri08.bsky.social (@embl.org) nos ofrecen una conversación estimulante sobre el estado actual del campo de las células vivas y el poder de los enfoques multidisciplinares en el tercer episodio de #ScienceWithAView.

Más info 👇

📣We are looking for an enthusiastic postdoctoral candidate to work on an interdisciplinary project on biophysics of extremophiles!

🤝A collaboration with Donato Giovannelli @donatogiovannelli.bsky.social and Vikas Trivedi @viktri08.bsky.social

📩Contact: Maria.Garcia@embl-hamburg.de

Cell-cell communication controls the timing of gastruloid symmetry-breaking In the embryo, morphogenetic signals instruct regional patterning thereby defining the body axes of the future animal. Remarkably, in the absence of such signals, collections of pluripotent stem cells...

Really happy to share with you my last work from my time in @embl.org with the @viktri08.bsky.social group. We studied the dynamics of cell fate transition in gastruloids and found that cells communicate with each other to control the timing of symmetry breaking. www.biorxiv.org/content/10.1...

Cell-cell communication controls the timing of gastruloid symmetry-breaking In the embryo, morphogenetic signals instruct regional patterning thereby defining the body axes of the future animal. Remarkably, in the absence of such signals, collections of pluripotent stem cells...

And because it really is Christmas, another study by @davidoriola.bsky.social and @viktri08.bsky.social lab showing how cell-cell communication can drive the timing of symmetry breaking!
www.biorxiv.org/content/10.1...

Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism There is an integral relationship between the mechanical behaviour of cells and tissues and their cellular metabolism. Exter...

Shout out to the leading authors and their teams @bernasozen.bsky.social , @DanuserLab, @CantleyLab and Gerburg Wulf, @siriodupont @ebisuyamiki.bsky.social @kstapornwongkul.bsky.social @viktri08.bsky.social
Also check out this workshop: www.biologists.com/workshops/ju... by @Co_Biologists

Congratulations, Olivier Duss, Simone Köhler, and Eva Kowalinski! 👏

The three EMBL Group Leaders have received ERC Consolidator Grants #ERCCoG for their innovative research projects aimed at understanding fundamental cellular mechanisms.

#MolBiol 🧪👇
Read more here: www.embl.org/news/awards-...

‘Cue-less’ symmetry breaking in gastruloids

Read this Research Highlight showcasing work from Kerim Anlaş, Nicola Gritti, Vikas Trivedi @viktri08.bsky.social and colleagues:
journals.biologists.com/dev/article/...

🎥Onset of T expression in gastruloids

Elevated temperature fatally disrupts nuclear divisions in the early Drosophila embryo Temperature variations can challenge animal survival, with different life cycle stages presenting distinct vulnerabilities to elevated temperature. Here, embryonic development is known to be especiall...

Our recent preprint on how elevated temperatures affect early embryo development. We are using fly embryos to address this fundamental question, and seeing mitotic defects, which can be rescued to improve embryo survival.

doi.org/10.1101/2023...

It was a fun discussion on the present of #DevBio #StemCells and #NotInTheGenes w/ @viktri08.bsky.social shorturl.at/P1rlz Very happy we got a chance to touch on the situation of students and postdocs in labs. Thank you @c_n_george and #ScienceWithAView

Cover: Development of transgenic Lytechinus pictus, the first transgenic echinoderm lines, expressing cyan fluorescent protein fused to a nuclear marker (histone 2B) driven by a polyubiquitin promoter. Developmental stages expressing the transgene are depicted from blastula (12 h post-fertilisation) through the larval stages, to the competent larva (22 days post-fertilisation), and finally to the juvenile stage at center. The juvenile has an additional membrane stain (grey) for contrast. See Research article by Jackson et al. (dev202991). Image credit: Svenja Kling, Yoon Lee and Elliot Jackson; Hamdoun Laboratory.

Development’s Special Issue 'Uncovering Developmental Diversity' is now complete. #DevSIDiversity

Explore the full ToC, including review-type articles and research papers highlighting 32 different organisms from across the multicellular tree of life:

journals.biologists.com/dev/issue/15...

Out today in Nature: "The Human Cell Atlas"! In my News and Views, I compare the cell atlas to early naturalists creating an atlas of South America. Researchers mining this cell atlas can now make big discoveries, just as the next naturalists then discovered evolution.
www.nature.com/articles/d41...

From head to tail: how cells give rise to our body plan | EMBL Researchers from the Trivedi Group at EMBL Barcelona unveil how cells can act autonomously during early development.

Thanks to @carlamanzanas.bsky.social at @embl.org for this explanation of our work
www.embl.org/news/science...

"Train people well enough so they can leave, treat them well enough so they don't want to leave"

Couldn't agree more!

My first post on @bsky.app. So happy to announce that our work has been published in Development by @biologists.bsky.social
doi.org/10.1242/dev....

Also a big thanks for "The people behind the papers" article as well! doi.org/10.1242/dev....