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Posts by Duncan MacCannell

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Sobering talk from Timothy Walsh from Oxford, UK on the rising antibacterial resistance even to the NOVEL agents

For example we are already seeing growing reports of Cefiderocol resistance - and we have barely started using it.

As usual we are being outrun by the bacteria

#EscmidGlobal2026

22 hours ago 22 10 2 1
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Here they both are as they powered up Heartbreak Hill.

1 day ago 1 0 0 0

A bittersweet congratulations, Adam! Hope to come visit when you are settled.

2 days ago 3 0 1 0
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Why scientists are nervous about fungi They can pose a threat to human health — yeast infections are but one example. Scientists say not enough attention is paid to their ability to develop resistance to medications that treat them.

They can pose a threat to human health — yeast infections are but one example. Scientists say not enough attention is paid to their ability to develop resistance to medications that treat them.

3 days ago 234 64 15 10
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At least 5 dead in Burundi from a mystery illness: Africa CDC Lab tests are negative for more than 200 pathogens, but testing continues.

www.cidrap.umn.edu/misc-emergin...

4 days ago 2 1 1 0
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San Francisco reports first case of more severe mpox strain San Francisco public health officials have confirmed the city’s first case of clade I mpox in an unvaccinated adult who was in contact with someone who had traveled internationally.

San Francisco public health officials have confirmed the city’s first case of clade I mpox in an unvaccinated adult who was in contact with someone who had traveled internationally.

4 days ago 10 7 0 2
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Mpox emergence, epidemiology, biology, clinical features and control Nature Reviews Microbiology, Published online: 08 April 2026; doi:10.1038/s41579-026-01305-yIn this Review, Ogoina et al. examine the emergence of mpox and its epidemiology, the viral life cycle, transmission dynamics, risk factors and clinical characteristics. They also explore current and future prevention and control strategies, including the therapeutic and vaccine landscape, as well as the urgent need for integrated surveillance, equitable access to countermeasures, and Africa-led research to address the ongoing multi-clade threat.

ICYMI: New online! Mpox emergence, epidemiology, biology, clinical features and control

6 days ago 3 2 0 0

It is, after all, the final frontier.

1 week ago 0 0 0 0

NASA has much better swag.

1 week ago 3 0 1 0

Federal science programs rock.

1 week ago 10 0 0 0
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The Artemis II crew emerges after a safe splashdown off the coast of California, concluding a historic journey around the moon. https://cnn.it/41qt7BW

1 week ago 286 50 8 5
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Turnstile guy is my spirit animal

1 week ago 5 0 0 0

Amazing!

1 week ago 1 0 0 0

Still holding my breath.

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Lyme disease is spreading—a new vaccine could curb infections A new Lyme disease vaccine made by Pfizer and Valneva could lower infection rates of the tick-borne illness, but federal approval and patient uptake could be a challenge

www.scientificamerican.com/article/lyme...

1 week ago 5 1 0 0
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Emergence of Extensively Drug-Resistant Shigellosis This report describes the emergence of drug-resistant shigellosis in the United States during 2011-2023.

www.cdc.gov/mmwr/volumes...

1 week ago 3 2 1 0

Request for Information: Suspected mpox clade 1b cluster detected in Khairpur, Sindh, Pakistan with neonatal ca...
beaconbio.org/en/report/

2 weeks ago 0 2 0 1
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Really cool.

2 weeks ago 6 2 0 0

Everything gas is fire.

2 weeks ago 1 0 0 0
Mpox cases (weekly)

Mpox cases (weekly)

The Democratic Republic of the Congo (DRC) has officially declared the end of the mpox epidemic

Read more at: beaconbio.org/en/report/

2 weeks ago 10 2 0 0
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Vaccination Coverage by Age 24 Months Among Children Born ... This report describes vaccination coverage by age 2 among ...

www.cdc.gov/mmwr/volumes...

2 weeks ago 8 5 0 0

Finding yourself at a Waffle House without a clear explanation of how you got there is actually a pretty common experience.

2 weeks ago 13 0 0 1
Text reasoning and response of the gemma4 (e4b) model responding to a user request to assist in the production of a potential biowarfare agent.

Text reasoning and response of the gemma4 (e4b) model responding to a user request to assist in the production of a potential biowarfare agent.

Interesting (to me at least!) to see what goes on under the hood of some of the newer frontier AI models — particularly those that can run off-network and with modest computational specs.

Here’s the brand new gemma4 (e4b), reasoning through a clear request to violate bio security guardrails.

2 weeks ago 6 1 5 0
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Don’t Get Sucked Into the War on Lice It hasn’t been going well.

This seems weirdly pro-lice.

www.theatlantic.com/science/2026...

3 weeks ago 0 1 0 0
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The Horrors That Could Lie Ahead if Vaccines Vanish Researchers at Stanford University modeled how many people could die or be disabled in 25 years if vaccines for polio, measles, rubella or diphtheria were no longer available.

Over the last 25 years, six people who contracted measles in the U.S. died from it.

A model built by Stanford researchers predicts that if Americans could no longer get the vaccine, measles could kill about 290,000 people in the next 25 years.

3 weeks ago 1148 618 58 38
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These days, my SV bagels are just as quick as FedEx delivers them. Which is usually at least a day or two. :(

1 month ago 1 0 1 0

I was going to say. You used to be able to tell Ste. Viateur from the way they did they applied the poppyseeds, but I guess that’s pretty operator dependent.

1 month ago 4 0 2 0
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Early Detection and Surveillance of the SARS-CoV-2 ... This report describes early detection and surveillance ...

Update on SARS-CoV-2 BA.3.2 in the US.
www.cdc.gov/mmwr/volumes...

1 month ago 4 1 0 0
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Timeline cleanse.

1 month ago 7 0 0 0
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FDA’s top infectious disease regulator to depart agency Adam Sherwat, the director of the Office of Infectious Diseases in the FDA’s Center for Drug Evaluation and Research, is leaving the agency.

www.statnews.com/2026/03/18/f...

1 month ago 1 0 0 0