And find out more about the programme and how to apply here 👉 edin.ac/3EKJuBd

Science Insights - a message from our alumni In 2025 we invited Science Insights participants from years gone by to come back and chat to us about their experience of the programme and how it helped them to be where they are now. Here's what the...

Applications for our Science Insights programme close next Friday!
Hear from some of our alumni about how it gives S5 students a real insight into working as a researcher in biological, biomedical and animal sciences 👉 edin.ac/4tsFLMX
@cmvm-edinburghuni.bsky.social

Congratulations to Asier Unciti-Broceta!
@cmvm-edinburghuni.bsky.social
@edinburgh-uni.bsky.social

Congratulations Tom!
@deeganlab.bsky.social
@cmvm-edinburghuni.bsky.social
@edinburgh-uni.bsky.social

Study supports link between physical injury and mental health | Institute of Genetics and Cancer | Institute of Genetics and Cancer Research investigating whether physical injury leads to chemical changes in our DNA – specifically through a process called DNA methylation – could help identify those people most at risk of developin...

A new study investigated whether physical injury leads to chemical changes in our DNA – specifically through a process called DNA methylation – in a bid to identify those people most at risk of developing mental health issues after a trauma 👉 edin.ac/4sR43iN
@cmvm-edinburghuni.bsky.social

Very pleased to say that the paper version of our study examining the role of de novo DNMTs in cancer-associated hypomethylation is now out in @plos.org Genetics 🎉:
doi.org/10.1371/jour...
You can read more on the previous thread but here is a summary of the main updates! #epigenetics 🧵 1/9

Sabotaging cancer could open doors to new treatments | Institute of Genetics and Cancer | Institute of Genetics and Cancer Researchers at the Institute of Genetics and Cancer are launching a £1.5 million Cancer Research UK-funded study to find a way to ‘trick’ bowel cancer cells.

April is Bowel Cancer Awareness Month.
Researchers at IGC are carrying out a £1.5 million @cancerresearchuk.org-funded study to find a way to ‘trick’ bowel cancer cells.
Learn more about how sabotaging cancer could open doors to new treatments 👇 edin.ac/4c61KBP
@cmvm-edinburghuni.bsky.social

The landscape of hereditary haemochromatosis risk and diagnosis across the British Isles and Ireland - Nature Communications Here the authors analyse genetic data for over 400,000 British and Irish people, showing that the frequency of the major genetic risk factor for haemochromatosis varies from a low of 1/212 in Southern...

New Publication:
The landscape of hereditary haemochromatosis risk and diagnosis across the British Isles and Ireland

@uoe-igc.bsky.social

www.nature.com/articles/s41...

“It doesn’t seem that long, but mirrors argue otherwise.”
Dr Chris Boyd is retiring after starting work at the University of Edinburgh 40 years ago.
You can read more about his long career here 👉 edin.ac/4dkCom5
@cmvm-edinburghuni.bsky.social

Read more about Luke Boulter's project 👉 edin.ac/4m5PPbS

Huge congratulations to Luke Boulter @boulterlab.bsky.social who has been awarded a Senior Cancer Research Fellowship!
edin.ac/4cmZZR9

Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signaling - Nature Genetics Saturation genome editing of a cancer mutation hotspot in CTNNB1, the gene encoding β-catenin, reveals a gradient of effects of missense mutations on Wnt signaling.

New Publication:
Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signaling

@roslininstitute.bsky.social @uoe-igc.bsky.social @edinuni-irr.bsky.social @cruk-si.bsky.social

www.nature.com/articles/s41...

Life with TSW: 'Our skin is falling off and no-one can tell us why ' People sharing pictures and accounts on socials of red, inflamed skin have triggered the first UK research into TSW.

Symptoms of topical steroid withdrawal (TSW) include "thickening and laxity of the skin, so-called 'elephant skin', extreme shedding and sharply defined areas of redness" says Sara Brown who has been funded by the National Eczema Society to look into topical steroid withdrawal (TSW).
edin.ac/4bHKPXm

Today, we had the pleasure of hosting Dr. Riccardo Marioni from @uoe-igc.bsky.social at our #SeminarsIN with his talk: “Tracking brain health from saliva and blood samples”.
A fantastic lecture, thank you! 👏👏
@csic.es @dicv.csic.es @umh.es

Gout is on the rise, with global cases increasing significantly over the past few decades. Researchers at IGC are looking for adults with gout to take part in a 1-to-1 recorded interview to better understand patient expectations and experiences of management of gout.
Read more 👉 edin.ac/4bSEnf5

Totally recommend this seminar with Riccardo!

As part of our EMS300 celebrations, IGC affiliates Kenneth Baillie and Jim Flett Wilson will share their career and research journeys so far at an inaugural lecture in McEwan Hall on 24 April.
Find out more and reserve your place 👉 edin.ac/4ro1aoz
@cmvm-edinburghuni.bsky.social

Incidence of ME peaks in adolescence or early middle age | Institute of Genetics and Cancer | Institute of Genetics and Cancer Researchers have found strong evidence that people are most likely to develop ME/CFS at two points in life, in a study that could help uncover causes of the disease and point to ways to prevent it.

Did you know there is strong evidence that people are most likely to develop ME/CFS at two points in life - at an average of age of 16 or 37?
Read more about this new study led by @aryback.bsky.social 👉 edin.ac/4v3uIv0

Neanderthal DNA can help explain how human faces form Scientists are using the DNA of extinct Neanderthals to understand how modern human faces have evolved. They have isolated the region that is better at activating a jaw-forming gene in Neanderthals an...

IGC's @hannahlong.bsky.social talks about how the study of Neanderthal DNA can help explain how human faces form in this interview with CBC Radio Canada 👇
www.cbc.ca/player/play/...
@cmvm-edinburghuni.bsky.social

Why a 28-year-old with brain cancer donated part of his living brain For the first time, researchers have been able to study how a living brain interacts with Alzheimer’s proteins in real time – and how parts of the brain are ...

Are you a medical student interested in an academic career? Then apply for the CRUK TRACC MB-PhD programme by 2 April. Current student Alsadeg Bilal has recently seen some of his research featured on CNN 👉 edin.ac/4rwIhQG
More information and apply here: edin.ac/4kmBIyc

Institute of Genetics and Cancer inaugural lecture showcase | College of Medicine & Veterinary Medicine | College of Medicine and Vet Medicine A recording of the inaugural lecture showcase from the Institute of Genetics and Cancer.

If you missed our Inaugural Lectures featuring Professor of Computational Protein Biology @jmarshlab.bsky.social and Professor of Computational Biology @csemple.bsky.social, you can catch up on their career journeys and research in genomics, cancer and computational biology here 👉 edin.ac/3P86GhY

Read more about this important paper which indicates a key driving role for Crohn's Lymphoid Aggregates (CLAs) in fibrosis and probably in the chronic inflammatory processes leading up to fibrosis. 👉 edin.ac/415XFsa
@cmvm-edinburghuni.bsky.social
@edinburgh-uni.bsky.social

Advanced Applications of Sequencing Technologies - thank you to all of our speakers and organisers

@jrossfitz.bsky.social @natalieannering.bsky.social @pathogenomenick.bsky.social @adelaam.bsky.social @uoe-eid.bsky.social @uoe-igc.bsky.social @roslininstitute.bsky.social @uoecolscieng.bsky.social

Join us tonight for a @cmvm-edinburghuni.bsky.social Inaugural Lecture to learn how advances in DNA sequencing, AI-based modelling & large-scale genome analysis are improving genetic diagnosis, deepening our understanding of tumour evolution & shaping targeted treatments. Book here 👉 edin.ac/4tPhvoY

Photo of Lana Talmane in a cycling helmet in the countryside

Dr Lana Talmane is a Postdoctoral Researcher in Professor @mstaylor.bsky.social's research group at IGC. In this interview with One Health Genomics Edinburgh, she talks about her work on mutations in the non-coding genome, her career so far, and interests outside of science 👉 edin.ac/3P3Uyyj

Cartoon of a scientist writing at a computer while reading a grey scientific article and thinking of other diverse scientific papers.

Our new Editorial from EiC Liz Patton @uoe-igc.bsky.social urges you to CITE IT RIGHT!

Citations hold immense power in shaping the history of a field & the success of careers. Accurate & CONSIDERATE citation of the literature is vital!
doi.org/10.1242/dmm....

Shining A Light on Rare Disease Recording of the Rare Disease Day 2026 Shining A Light on Rare Disease eventAI and Rare Disease: Discovering the Missing Pieces

For #RareDiseaseDay2026, we looked at the different approaches to researching rare disease, and the challenges and opportunities afforded by Artificial Intelligence models.
You can catch up on the event here 👉 edin.ac/4sugwJk
edin.ac/4sugwJk
@cmvm-edinburghuni.bsky.social

Read our webstory 👉 edin.ac/4sC84rA

IGC is looking for two Postdoctoral Research Fellows in Molecular Epidemiology for the MRC-funded grant 'Blood-and saliva-based DNA methylation biomarkers of disease' which will explore epigenetic biomarkers of organ ageing, proteins & disease. More info & apply here by 20 March 👉 edin.ac/4aYx7Pt

Well done to all the teams, including team CAUSE with @mstaylor.bsky.social from IGC!